Department of Public Health Kansanterveystieteen laitos

Kansanterveystieteen laitos Department of Public Health PL 41 (Mannerheimintie 172) 00014 Helsingin Yliopisto University of Helsinki Department of Public Health Kansanterveystieteen laitos Publications 2006 Julkaisut 2006 Sirkka Koskinen (ed.) Kansanterveystieteen laitos Department of Public Health Helsinki 29.1.2007 1

Publications of the Department of Public Health 2006 Kansanterveystieteen laitoksen julkaisut 2006 Scientific or scholarly monographs and all dissertations, even if they are published in a department series, A1 Barengo N. Physical activity, cardiovascular risk factors and mortality. Kuopio University Publications D. Medicine Sciences 377. Kuopio: Kopijyvä, Univ. of Kuopio and Univ. of Helsinki, 2006. 107 p. ISBN 951-27-0397-1. ISBN 951-27- 0474-9 (pdf). ISSN 1235-0303. Borodulin K. Physical activity, fitness, abdominal obesity, and cardiovascular risk factors in Finnish men and women. Publications of the National Public Health Institute A1/2006. Helsinki: Edita Prima Oy, Univ. of Helsinki, 2006. 95 p. ISBN 951-740-585-5. ISSN 0359-3584. ISBN 951-740-586-3 (pdf). ISSN 1458-6290 (pdf). http://ethesis.helsinki.fi/ Bäckmand H. Fyysisen aktiivisuuden yhteys persoonallisuuteen, mielialaan ja toimintakykyyn. Pitkäaikaisseurantatutkimus ikääntyvillä miehillä. Kansanterveystieteen julkaisuja M 188:2006. Helsinki: Yliopistopaino, Univ. of Helsinki, 2006. 109 p. ISBN 952-10-1370-2. ISSN 0355-7979. ISBN 952-10-2885-8 (pdf). http://ethesis.helsinki.fi/ Hemilä H. Do vitamins C and E affect respiratory infections? Helsinki: Yliopistopaino, Univ. of Helsinki, 2006. 131 p. ISBN 952-91-9700-4. ISBN 952-10-2837-8 (pdf). http://ethesis.helsinki.fi/ Kaila-Kangas L. Socioeconomic status, occupational factors and life style as predictors of hospitalisation for back disorders. Työterveyslaitos. 2006. ISBN 951-802-678-5. Lindström J. Prevention of type 2 diabetes with lifestyle intervention emphasis on dietary composition and identification of high-risk individuals. Publications of the National Public Health Institute KTL A18/2006. Helsinki: Edita Prima Oy. 125 p. ISBN 951-740-655-x. ISSN 0359-3584. ISBN 951-740-656-8 (pdf). ISSN 1458-6290 (pdf). Ojajärvi A. Occupational determinants of pancreatic cancer. Finnish Institute of Occupational Health. People and Work. Research Reports 75. Helsinki: Tampereen yliopistopaino, Univ. of Helsinki, 2006. 106 p. ISBN 951-802-730-7. 978-951-802-730-3. PDF: 951-802-731-5, 978-951-802-731- 0. ISSN 1237-6183. http://ethesis.helsinki.fi/ Paavola M. Smoking from adolescence to adulthood. A 15-year follow-up of the North Karelia youth project. Publications of the National Public Health 2

Institute A16/2006. Helsinki: Edita Prima Oy, Univ. of Helsinki, 2006. 69 p. ISBN 951-740-629-0. ISSN 0359-3584. ISBN 951-740-630-4 (pdf). ISSN 1458-6290 (pdf). http://ethesis.helsinki.fi/ Penninkilampi-Kerola V. Implications of co-twin dependence for twins social interactions, mental health and alcohol use. Kansanterveystieteen julkaisuja M-sarja 180:2006. Oulu: Oulun yliopiston paino, Univ. of Oulu, 2006. 80 p. ISBN 952-10-1372-9. ISSN 0355-7979, ISBN 952-10-3194-8 (pdf). http://ethesis.helsinki.fi/ Ropponen A. The role of heredity, other constitutional structural and behavioral factors in back function tests. Studies in sport, physical education and health 111. Jyväskylä: Jyväskylä University Printing House, Univ. of Jyväskylä and Univ. of Helsinki, 2006. 78 p. ISBN 951-39-2396-7 (pdf). ISBN 951-39-2367-3. ISSN 0356-1070. Sintonen H, Pekurinen M. Terveystaloustiede, WSOY, Helsinki 2006. ISBN 951-0- 31744-6. Vuorinen HS. Tautinen Suomi 1851-1865. Vaajakoski: Gummerus Kirjapaino Oy, 2006:208. ISBN 951-44-6495-8. Scientific or scholarly monographs edited or translated by the person, whose authorship is to recorded, A3 Harkonmäki K, Lahelma E, Väänänen J, Rahkonen O. Eläkeaikomukset ja varhaiseläkkeelle siirtyminen Helsingin kaupungin henkilöstön keskuudessa. Helsingin Kaupungin Tietokeskus. Tutkimuskatsauksia 2006:4:38. ISBN 952-473- 756-6. ISSN 1455-7266. Lauridsen J, Christiansen T, Gundgaard J, Häkkinen U, Sintonen H. Decomposition of socio-economic determination of income-related health inequality by health dimensions. Discussion papers on business and economics no. 8/2006. 2006:24. ISBN 87-91657-07-5. http://www.sam.sdu.dk/depts/virkl/about.shtml Pulkkinen L, Kaprio J, Rose RJ. Socioemotional development and health from adolescence to adulthood. New York: Cambridge University Press. 2006. 1-421 pp. ISBN-13: 978-0-521-84631-8. Räsänen P, Roine E, Sintonen H, Semberg-Konttinen V, Ryynänen O-P, Roine RP. Laatupainotetut elinvuodet terveydenhuollon vaikuttavuuden arvioinnissa: Järjestelmällinen kirjallisuuskatsaus (Use of quality-adjusted life years for the estimation of effectiveness of health care: a systematic literature review). Finohtan raportti (Finohta s report) 29, Helsinki: Stakes, 2006. Utriainen I, Sarlio-Lähteenkorva S, Aittomäki A, Lahelma E. Lihavuus ja keskivartalolihavuus Helsingin kaupungin henkilöstön keskuudessa. Helsingin 3

Kaupungin Tietokeskus. Tutkimuskatsauksia 2006:1:41. ISBN 952-473-626-8. ISSN 1455-7266. Wiens J-E, Aittomäki A, Lahelma E. Sydän- ja verisuonitautien biologiset riskitekijät Helsingin kaupungin henkilöstön keskuudessa. Helsingin Kaupungin Tietokeskus. Tutkimuskatsauksia 2006:2:32. ISBN 952-473-627-6. ISSN 1455-7266. Scientific or scholarly articles in scientific or scholarly journals that use the referee evaluation system, B1 Ahveninen J, Jääskeläinen IP, Osipova D, Huttunen MO, Ilmoniemi RJ, Kaprio J, Lönnqvist J, Manninen M, Pakarinen S, Therman S, Näätänen R, Cannon TD. Inherited auditory-cortical dysfunction in twin pairs discordant for schizophrenia. Biol Psychiatry 2006;Sep 15;60:6:612-20. Impact factor 6.779 Aittomäki A, Lahelma E, Rahkonen O, Leino-Arjas P, Martikainen P. The contribution of musculoskeletal disorders and physical workload to socioeconomic inequalities in health. Eur J Public Health 2006;5. Impact factor 1.118 Alemao E, Yin D, Sintonen H, Salomaa V, Jousilahti P. Evaluation of lipidlowering therapy and cholesterol goal attainment in Finland. The National FINRISK Study. Am J Cardiovasc Drugs 2006;6:5:349-55. Antikainen RL, Moltchanov VA, Chukwuma CSr, Kuulasmaa KA, Marques- Vidal PM, Sans S, Wilhelmsen L, Tuomilehto JO, for the WHO MONICA Project. Trends in the prevalence, awareness, treatment and control of hypertension: The WHO MONICA Project. European Journal of Cardiovascular Prevention & Rehabilitation 2006;13:1:13-29. Impact factor 2.333 Anttila V, Kallela M, Oswell G, Kaunisto MA, Nyholt DR, Hämäläinen E, Havanka H, Ilmavirta M, Terwilliger J, Sobel E, Peltonen L, Kaprio J, Färkkilä M, Wessman M, Palotie A. Trait components provide tools to dissect the genetic susceptibility of migraine. Am J Hum Genet 2006; Jul 79:1:85-99. Impact factor 12.649 Baker SG, Kaprio J. Common susceptibility genes for cancer: search for the end of the rainbow. BMJ 2006;332:1150-2. Impact factor 9.052 Barengo NC, Kastarinen M, Lakka T, Nissinen A, Tuomilehto J. Different forms of physical activity and cardiovascular risk factors among 24-64-year-old men and women in Finland. European Journal of Cardiovascular Prevention & Rehabilitation, 2006;13:1:51-9. Impact factor 2.333 Barengo NC, Nissinen A, Pekkarinen H, Halonen P, Tuomilehto J. Twenty-fiveyear trends in lifestyle and socioeconomic characteristics in Eastern Finland. Scandinavian Journal of Public Health 2006;34:437-44. Impact factor 0.727 4

Bidel S, Hu G, Qiao Q, Jousilahti P, Antikainen R, Tuomilehto J. Coffee consumption and risk of total and cardiovascular mortality among patient with type 2 diabetes. Diabetologia 2006;49:2618-26. Impact factor 5.337 Bidel S, Hu G, Sundvall J, Kaprio J, Tuomilehto J. Effects of coffee consumption on glucose tolerance, serum glucose and insulin levels A cross-sectional analysis. Horm Metab Res 2006;38:38-43. Impact factor 2.049 Bonnycastle LL, Willer CJ, Conneely KN, Jackson AU, Burrill CP, Watanabe RM, Chines PS, Narisu N, Scott LT, Enloe ST, Swift AJ, Duren WL, Stringham HM, Erdos MP, Riebow NL, Buchanan TA, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Boehnke M, Collins FS. Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes 2006;Sep.55:9:2534-40. Impact factor 8.028 Borgström F, Carlsson Å, Sintonen H, Boonen S, Haentjens P, Burge R, Johnell O, Jönsson B, Kanis JA. The cost-effectiveness of risedronate in the treatment of osteoporosis: an international perspective. Osteoporos Int 2006;17:7:996-1007. Impact factor 4.216 Borodulin K, Tuomilehto J. Peltonen M, Lakka TA, Sundvall J, Jousilahti P. Association of leisure time physical activity and abdominal obesity with fasting serum insulin and 2-h postchallenge plasma glucose levels. Diabet Med 2006;23:1025-8. Impact factor 2.725 Blom M, Tuominen U, Seitsalo S, Malmivaara A, Hirvonen J, Hietaniemi K, Lehto M, Paavolainen P, Sintonen H, Rissanen P. Lonkan ja polven tekonivelleikkaushoidon vaikuttavuus. Satunnaistettu vertailututkimus nopeasti leikattujen ja ei-leikattujen (jonossa olevien) potilaiden välillä. Suomen Ortopedia ja Traumatologia 2006;29:331-5. Broms U, Madden PAF, Heath AC, Pergadia ML, Shiffman S, Kaprio J. The nicotine dependence syndrome scale in Finnish smokers. Drug and Alcohol Dependence 2006; Dec. 12. Impact factor 2.969 Broms U, Silventoinen K, Madden PAF, Heath AC, Kaprio J. Genetic architecture of smoking behavior: A study of Finnish adult twins. Twin Research and Human Genetics 2006;9:1:64-72. Bäckmand H, Kaprio J, Kujala UM, Sarna S, Fogelholm M. Physical and psychological functioning of daily living in relation to physical activity. A longitudinal study among former elite male athletes and controls. Aging Clinical and Experimental Research 2006;18:40-9. Impact factor 1.302 Cannon TD, Thompson PM, van Erp TGM, Huttunen M, Lönnqvist J, Kaprio J, Toga AW. Mapping heritability and molecular genetic associations with cortical brain atlases: Methods and applications to Schizophrenia. Neuroinformatics 2006;4:1:5-19. Impact factor 3.902 5

Ceriello A, Davidson J, Hanefeld M, Leiter L, Monnier L, Owens D, Tajima N, Tuomilehto J. Postprandial hyperglycaemia and cardiovascular complications of diabetes: An update. Nutr Metab Cardiovasc Dis 2006;16:453-6. Impact factor 1.482 Dalstra JAA, Kunst AE, Mackenbach JP, The EU Working Group on Socioeconomic Inequalities in Health (Lahelma E.). A comparative appraisal of the relationship of education, income and housing tenure with less than good health among the elderly in Europe. Social Science & Medicine 2006;62:2046-60. Impact factor 2.619 The Decode Study Group, Qiao Q, Pitkäniemi J, Tuomilehto J, Gao WG. Comparison of different definitions of the metabolic syndrome in relation to cardiovascular mortality in European men and women. Diabetologia 2006;49:2837-46. Impact factor 5.337 The Decode Study Group, Balkau B, Qiao Q, Tuomilehto J, Borch-Johnsen K, Pyörälä K. Does diagnosis of the metabolic syndrome detect further men at high risk of cardiovascular death beyond those identified by a conventional cardiovascular risk score? European Journal of Cardiovascular Prevention and Rehabilitation (in press). Impact factor 2.333 The DECODA Study Group, Nyamdorj R, Qiao Q, Tuomilehto J, Gao WG, Nakagami T, Tajima N, Hammer N, Johansson S. Prevalence of metabolic syndrome in populations of Asian origin. Diabetes Research and Clinical Practice 2006. Impact factor 1.236 Diamond Project Group (Tuomilehto J) Incidence and trends of childhood type 1 diabetes worldwide 1990-1999. Diabet Med 2006;23:L857-66. Impact factor 2.725 Dick DM, Rose RJ, Kaprio J. The next challenge for psychiatric genetics: Characterizing the risk associated with identified genes. Annals of Clinical Psychiatry 2006;18:4:223-31. Eriksson JG. Early growth, and coronary heart disease and type 2 diabetes: experiences from the Helsinki Birth Cohort Studies. International Journal of Obesity 2006;30,S18-S22. Impact factors 4.482 Eriksson JG. Mistä tyypin 2 diabetes johtuu?. Suomen Lääkärilehti 2006;61:38:3823. Eriksson JG, Lehtovirta M, Ehrnström B, Salmela S, Groop L. Long-term beneficial effects of glipizide treatment on glucose tolerance in subjects with impaired glucose tolerance. Journal of Internal Medicine 2006;259:553-60. Impact factor 4.040 Eriksson JG, Osmond C, Kajantie E, Forsén T, Barker DJP. Patterns of growth among children who later develop type 2 diabetes or its risk factors. Diabetologia 2006;49:2853-8. Impact factor 5.337 Eskelinen A, Remes V, Helenius I, Pulkkinen P, Nevalainen J, Paavolainen P. Uncemented total hip arthroplasty for primary osteoarthritis in young patients: a mid- 6

to long-term follow-up study from the Finnish Arthroplasty Register. Acta Orthop 2006;77:1:57-70. Impact factor 1.157 Feldt T, Lintula H, Suominen S, Koskenvuo M, Vahtera J, Kivimäki M. Structural validity and temporal stability of the 13-item sense of coherence scale: Prospective evidence from the population-based HeSSup study. Quality of Life Research 2006. Impact factor 1.915 Forouhi NG, Balkau B, Borch-Johnsen K, Dekker J, Glumer C, Qiao Q, Spijkerman A, Stolk R, Tabac A, Wareham NJ, on behalf of the EDEG. The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group. Diabetologia 2006;49:822-7. Impact factor 5.337 Granér M, Kahri J, Nakano T, Sarna SJ, Nieminen MS, Syvänne M, Taskinen MR. Impact of postprandial lipaemia on low-density lipoprotein (LDL) size oxidized LDL in patients with coronary artery disease. European Journal of Clinical Investigation 2006;36:11:764-70. Impact factor 2.684 Hannukainen JC, Nuutila P, Kaprio J, Heinonen O, Kujala UM, Janatuinen T, Rönnemaa T, Kapanen J, Haaparanta-Solin M, Viljanen T, Knuuti J, Kalliokoski KK. Relationship between local perfusion and FFA uptake in human skeletal muscle no effect of increased physical activity and aerobic fitness. J Appl Physiol 2006; Jul 6:101:5:1303-11. Impact factor 3.037 Hannukainen JC, Nuutila P, Borra R, Kaprio J, Kujala UM, Janatuinen T, Heinonen OJ, Kapanen J, Viljanen T, Haaparanta M, Rönnemaa T, Parkkola R, Knuuti J, Kalliokoski KK. Increased physical activity decreases hepatic free fatty acid uptake: a study in monozygotic twins. J Physiol 2007;5:78;346-58. Impact factor 4.272 Harjutsalo V, Reunanen A, Tuomilehto J. Differential transmission of type 1 diabetes from diabetic fathers and mothers to their offspring. Diabetes 2006;55:1517-24. Impact factor 8.028 Harkonmäki K, Korkeila K, Vahtera J, Kivimäki M, Suominen S, Sillanmäki L, Koskenvuo M. Childhood adversities as a predictor of disability retirement. JECH (in press). Harkonmäki K, Rahkonen O, Martikainen P, Silventoinen K, Lahelma E. Associations of SF-36 mental health functioning and work and family related factors with intentions to retire early among employees. Occup Environ Med 2006 Aug;63:8:558-63. Impact factor 1.934 Harkonmäki K, Lahelma E, Martikainen P, Rahkonen O, Silventoinen K. Mental health functioning (SF-36) and intentions to retire early among ageing municipal employees: The Helsinki Health Study. Scandinavian Journal of Public Health 2006;34:2:190-8. Impact factor 0.727 7

Heinonen-Guzejev M, Vuorinen HS, Mussalo-Rauhamaa H, Heikkilä K, Koskenvuo K, Kaprio J. The association of noise sensitivity with coronary heart and cardiovascular mortality among Finnish adults. Science of the Total Environment 2007;372:406-12. Impact factor 2.224 Heinävaara S, Hakulinen T. Predicting the lung cancer burden: Accounting for selection of the patients with respect to general population mortality. Statistics in Medicine 2006;25:2967-80. Impact factor 1.477 Helasoja V, Lahelma E, Prättälä R, Kasmel A, Klumbiene J, Pudule I. The sociodemographic patterning of health in Estonia, Latvia, Lithuania and Finland. European Journal of Public Health 2006;16:1:8-20. Impact factor 1.118 Helasoja V, Lahelma E, Prättälä R, Klumbiene J, Pudule I, Tekkel M. Trends in the magnitude of educational inequalities in health in Estonia, Latvia, Lithuania and Finland during 1994-2004. Public Health 2006 Sep;120:9:841-53. Impact factor 0.986 Helasoja VV, Lahelma E, Prättälä RS, Patja KM, Klumbiene J, Pudule I, Kasmel A. Determinants of daily smoking in Estonia, Latvia, Lithuania, and Finland in 1994-2002. Scand J Public Health 2006;34:4:353-62. Impact factor 0.727 Helenius I, Remes V, Salminen S, Valta H, Mäkitie O, Holmberg C, Palmu P, Tervahartiala P, Sarna S, Helenius M, Peltonen J, Jalanko H. Incidence and predictors of fractures in children after solid organ transplantation: a 5-year prospective, population-based study. J Bone Miner Res 2006;21:3:380-7. Impact factor 6.527 Helenius I, Jalanko H, Remes V, Sairanen H, Salminen S, Holmberg C, Palmu P, Tervahartiala P, Valta H, Sarna S, Helenius M, Mäkitie O, Peltonen J. Scoliosis after solid organ transplantation in children and adolescents. American Journal of Transplantation 2006;6:324-30. Impact factor 6.002 Hemilä H, Kaprio J, Albanes D, Virtamo J. Physical activity and the risk of pneumonia in male smokers administered vitamin E and -carotene. Int J Sports Med 2006;27:4:336-41. Impact factor 1.433 Hemilä H, Virtamo J, Albanes D, Kaprio J. The effect of vitamin E on common cold incidence is modified by age, smoking and residential neighborhood. J Am Coll Nutr 2006;25:4:332-9. Impact factor 2.206 Hemilä H. C-vitamiini ja hengitystieinfektiot: Duodecim 2006;122:2062-3. Herder C, Peltonen M, Koenig W, Kräft I, M ller-scholze S, Martin S, Lakka T, Ilanne-Parikka P, Eriksson JG, Hämäläinen H. Keinänen-Kiukaanniemi S, Valle TT, Uusitupa M, Lindström J, Kolb H, Tuomilehto J for the Finnish Diabetes Prevention Study Group. Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes. Diabetes 2006;55:2340-6. Impact factor 8.028 8

Hildén HM, Honkasalo ML, Louhiala P. Finnish doctors and the realisation of patient autonomy in the context of end-of-life decision making. Journal of Medical Ethics 2006;32:316-20. Impact factor 1.312 Hirvonen J, Blom M, Tuominen U, Seitsalo S, Lehto M, Paavolainen P, Hietaniemi K, Rissanen P, Sintonen H. Health-related quality of life in patients waiting for major joint replacement. A comparison between patients and population controls. Health and Quality of Life Outcomes 2006;Jan 19:4:3. Hirvonen J, Blom M, Tuominen U, Sintonen H, WHJR Study Group. The use of patient-reported outcomes (PROs) in patients who underwent major joint replacement and those who left the queue. Patient Reported Outcomes Newsletter 2006;nr 36:31-3. Hirvonen J, Blom M, Tuominen U, Seitsalo S, Paavolainen P, Lehto MUK, Hietaniemi K, Rissanen P, Sintonen H. Lonkan ja polven tekonivelleikkaukseen jonottavien potilaiden sekä verrokkiväestön terveys- ja sosiaalipalvelujen käytön vertailua. Suomen Ortopedia ja Traumatologia 2006;29:350-2. Hirvonen J, van Erp TGM, Huttunen J, Någren K, Huttunen M, Aalto S, Lönnqvist J, Kaprio J, Cannon TD, Hietala J. Striatal dopamine D1 and D2 receptor balance in twins at increased genetic risk for schizophrenia. Psychiatry Research: Neuroimaging 2006;146:1:13-20. Impact factor 2.656 Hirvonen J, van Erp TG, Huttunen J, Aalto S, Nagren K, Huttunen M, Lönnqvist J, Kaprio J, Cannon TD, Hietala J. Brain dopamine d1 receptors in twins discordant for schizophrenia. Am J Psychiatry 2006;163:10:1747-53. Impact factor 8.286 Hjelmborg JvB, Iachine I, Skytthe A, Vaupel JW, McGue M, Koskenvuo M, Kaprio J, Pedersen NL, Christensen K. Genetic influence on human lifespan and longevity. Hum Genet 2006;119:3:312-21. Impact factor 4.331 Hu G, Jousilahti P, Nissinen A, Antikainen R, Kivipelto M, Tuomilehto J. Body mass index and the risk of Parkinson disease. Neurology 2006;67:1955-9. Impact factor 5.065 Hu G, Jousilahti P, Peltonen M, Bidel S, Tuomilehto J. Joint association of coffee consumption and other factors to the risk of type 2 diabetes: a prospective study in Finland. International Journal of Obesity 2006;12:1742-9. Impact factor 4.482 Hu G, Jousilahti P, Sarti C, Antikainen R, Tuomilehto J. The effect of diabetes and stroke at baseline and during follow-up on stroke mortality. Diabetologia 2006;Oct 49:10:2309-16. Impact factor 5.337 Hu G, Jousilahti P, Bordulin K, Barengo NC, Lakka TA, Nissinen A, Tuomilehto J. Occupational, commuting and leisure-time physical activity in relation to coronary heart disease among middle-aged Finnish men and women. Atherosclerosis 2006;15. Impact factor 3.777 9

Hu G, Lakka TA, Lakka H-M, Tuomilehto J. Lifestyle management in the metabolic syndrome. Metabolic Syndrome and Related Disorders 2006;4:270-86. Hu G, Rico-Sanz J, Lakka TA, Tuomilehto J. Exercise, genetics and prevention of type 2 diabetes. Essays Biochem 2006;42:177-92. Impact factor 3.217 Huth C, Heid IM, Vollmert, Gieger C, Grallert H, Wolford JK, Langer B, Thorand B, Klopp N, Hamid YH, Pedersen O, Hansen T, Lyssenko V, Groop L, Meisinger C, Döring A, Löwel H, Lieb W, Hengstenberg C, Rathmann W, Martin S, Stephens JW, Ireland H, Mather H, Miller GJ, Stringham HM, Boehnke M, Tuomilehto J, Boeing H, Möhling N, Spranger J, Pfeiffer A, Wernstedt I, Niklason A, L pez-bermejo A, Fernández-Real J, Hanson RL, Gallart L, Vendrell J, Tsiavou A, Hatziagelaki E, Humphries SE, Wichmann H- E, Herder C, Illig T. IL6 gene promoter polymorphisms and type 2 diabetes. Joint analysis of individual participants data from 21 studies. Diabetes 2006;55:2915-21. Impact factor 8.028 Huurre T, Aro H, Rahkonen O, Komulainen E. Health, lifestyle, family and school factors in adolescence: predicting adult educational level. Educational Research 2006;48:1:41-53. Impact factor 0.140 Huurre T, Eerola M, Rahkonen O, Aro H. Does social support affect the relationship between socioeconomic status and depression? A longitudinal study from adolescence to adulthood. Journal of Affective Disorders 2006. Impact factor 3.078 Hätönen KA, Similä ME, Virtamo JR, Eriksson JG, Hannila M-L, Sinkko HK, Sundvall JE, Mykkänen HM, Valsta LM. Methodologic considerations in the measurement of glycemic index: glycemic response to rye bread, oatmeal porridge, and mashed potato. Am J Clin Nutr 2006;84:1055-61. Impact factor 5.853 Idris BI, Giskes K, Borrell C, Benach J, Costa G, Federico B, Helakorpi S, Helmert U, Lahelma E, Moussa KM, Östergren P-O, Prättälä R, Rasmussen NKr, Mackenbach JP, Kunst AE. Higher smoking prevalence in urban compared to non-urban areas: Time trends in six European countries. Health & Place 2006. Impact factor 1.492 Ijäs P, Nuotio K, Saksi J, Soinne L, Saimanen E, Karjalainen-Lindsberg M-L, Salonen O, Sarna S, Tuimala J, Kovanen PT, Kaste M, Lindsberg PJ. Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques. Arteriosclerosis, thrombosis, and vascular biology. 2007;27:154-60. Impact factor 7.053 Jaakkola E, Herzberg I, Laiho K, Barnardo MCNM, Pointon JJ, Kauppi M, Kaarela K, Tuomilehto-Wolf E, Tuomilehto J, Wordsworth BP, Brown MA. Finnish HLA studies confirm the increased risk conferred by HLA-B27 homozygosity in ankylosing spondylitis. Ann Rheum Dis 2006;65:775-80. Jaakkola JJK, Ieromnimon A, Jaakkola MS. Interior surface materials and asthma in adults: a population-based incident case-control study. Am J Epidemiol 2006;164:7542-9. Impact factor 5.068 10

Jaakkola MS, Ieromnimon A, Jaakkola JJK. Are atopy and specific IgE to mites and molds important for adult asthma? J Allergy Clin Immunol 2006;117:642-8. Impact factor 7.667 Jula A, Kantola I, Koivisto P, Luostarinen E, Mervaala E, Niskanen L, Olkinuora J, Pyörälä K, Ruskoaho H, Tikkanen I, Tuomilehto J, Fyhrquist F, Keinänen-Kiukaanniemi S, Kukkonen-Harjula K, Majahalme S, Nieminen M, Nissinen A, Pentikäinen P, Romo M, Takala J, Tikkanen T, Turjanmaa V. Kohonnut verenpaine: Käypä hoito suosituksen tiivistelmä. Duodecim 2006;122:339-340. Kaipainen M, Broms U, Hosia-Randell H, Söderlund-Venermo M, Granér M, Heikman P, Öistämö H. Viihdyttäminen opetuksessa turhuutta vai tärkeä mauste? Suomen Lääkärilehti 2006;61:4:329-34. Kajantie E, Eriksson JG. Ensimmäisten elinvuosien kasvu ja myöhempi terveys. Duodecim 2006;122:6:621-3. Kajantie E, Phillips DIW, Osmond C, Barker DJP, Forsén T, Eriksson JG. Spontaneous hypothyroidism in adult women is predicted by small body size at birth and during childhood. The Journal of Clinical Endocrinology & Metabolism 2006;91:12:4953-6. Impact factor 6.020 Kaprio J. Twin studies in Finland 2006. Twin Research and Human Genetics 2006;9:6:772-7. Kaprio J. Lahjakkuuden monet ulottuvuudet. Duodecim 2006;122:23:2871-7. Karlsgodt KH, Glahn DC, van Erp TGM, Therman S, Huttunen M, Manninen M, Kaprio J, Cohen MS, Lönnqvist J, Cannon TD. The relationship between performance and fmri signal during working memory in patients with schizophrenia, unaffected co-twins, and control subjects. Schizophrenia Research 2007;89:191-7. Impact factor 4.231 Kastarinen MJ, Antikainen RL, Laatikainen TK, Salomaa VV, Tuomilehto JO, Nissinen AM, Vartiainen EA. Trends in hypertension care in eastern and southwestern Finland during 1982-2002. J Hypertens 2006;24:829-36. Impact factor 5.218 Kattainen E, Meriläinen P, Sintonen H. Sense of coherence and health-related quality of life among patients undergoing coronary artery bypass grafting or angioplasty. European Journal of Cardiovascular Nursing 2006;5:21-30. Kattainen E, Kettunen R, Sintonen H, Meriläinen P. Diabeetikon ohitusleikkaus ja pallolaajennus. Diabetes ja lääkäri 2006;35:3:10-7. Kaunisto MA, Kallela M, Hämäläinen E, Kilpikari R, Havanka H, Harno H, Nissilä M, Säkö E, Ilmavirta M, Liukkonen J, Teirmaa H, Törnwall O, Jussila M, Terwilliger J, Färkkilä M, Kaprio J, Palotie A, Wessman M. Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm 11

the association with migraine with aura. Cephalalgia 2006;26:12:1462-72. Impact factor 4.657 Kauppinen-Mäkelin R, Sane T, Sintonen H, Markkanen H, Välimäki MJ, Löyttyniemi E, Niskanen L, Reunanen A, Stenman U-H, the Finnish Acromegaly Study Group. Quality of life in treated patients with acromegaly. The Journal of Clinical Endocrinology & Metabolism 2006;91:10:3891-6. Impact factor 6.020 Keski-Rahkonen A, Sihvola E, Raevuori A, Kaukoranta J, Bulik CM, Hoek HW, Rissanen A, Kaprio J. Reliability of self-reported eating disorders: Optimizing population screening. Int J Eat Disord 2006;1239:8:754-62. Impact factor 1.915 Kestilä L, Koskinen S, Martelin T, Rahkonen O, Pensola T, Pirkola S, Patja K, Aromaa A. Influence of parental education, childhood adversities, and current living conditions on daily smoking in early adulthood. European Journal of Public Health 2006;16:6:617-26. Impact factor 1.118 Kestilä L, Koskinen S, Martelin T, Rahkonen O, Pensola T, Aro H, Aromaa A. Determinants of health in early adulthood: what is the role of parental education, childhood adversities and own education? European Journal of Public Health 2006;16:3:305-14. Impact factor 1.118 Kettunen JA, Kujala UM, Kaprio J, Sarna S. Health of master track and field athletes: A 16-year follow-up study. Clinical Journal of Sport Medicine 2006;16:2:142-8. Impact factor 2.783 Kilpeläinen M, Terho EO, Helenius H, Koskenvuo M. Body mass index and physical activity in relation to asthma and atopic diseases in young adults. Respiratory Medicine 2006;100:1518-25. Impact factor 1.663 Kivipelto M, Ngandu T, Laatikainen T, Winblad B, Soininen H, Tuomilehto J. Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study. Lancet Neurol 2006 Sep;5:9:735-41. Impact factor 23.878 Korhonen T, Kinnunen TH, Garvey AJ. Impact of nicotine replacement therapy on post-cessation mood profile by pre-cessation depressive symptoms. Tobacco Induced Diseases 2006;3:2:17-33. Korhonen T, Broms U, Varjonen J, Romanov K, Koskenvuo M, Kinnunen T, Kaprio J. Smoking behaviour as a predictor of depression among Finnish men and women: a prospective cohort study of adult twins. Psychological Medicine 2006:Dec 21:1-11. Impact factor 3.476 Korpela R, Tuomilehto J, Högström P, Seppo L, Piironen V, Salo-Väänänen P, Toivo J, Lamberg-Allardt C, Kärkkäinen M, Outila T, Sundvall J, Vilkkilä S, Tikkanen MJ. Safety aspects and cholesterol-lowering efficacy of low fat dairy products containing plant sterols. European Journal of Clinical Nutrition 2006;60:633-42. Impact factor 2.163 12

Koskinen H, Rautakorpi M, Sintonen H, Honkanen P, Huikko S, Huovinen P, Klaukka T, Palva E, Roine RP, Sarkkinen H, Varonen H, Mäkelä M, for the MIKSTRA Collaborative Study Group. Cost-effectiveness of implementing national guidelines in the treatment of acute otitis media in children. International Journal of Technology Assessment in Health Care 2006;22:454-9. Impact factor 0.725 Kousa A, Havulinna AS, Moltchanova E, Taskinen O, Nikkarinen M, Eriksson J, Karvonen M. Calcium: Magnesium ratio in local groundwater and incidence of acute mycardial infarction among males in rural Finland. Environmental Health Perspectives 2006;114:5:730-4. Kääpä EH, Frantsi K, Sarna S, Malmivaara A. Multidisciplinary group rehabilitation versus individual physiotherapy for chronic nonspecific low back pain. Spine 2006;31:4:371-6. Impact factor 2.187 Laaksonen M, Rahkonen O, Martikainen P, Lahelma E. Associations of psychosocial working conditions with self-rated general health and mental health among municipal employees. Int Arch Occup Environ Health 2006;79:3:205-12. Impact factor 1.482 Laaksonen M, Rahkonen O, Martikainen P, Karvonen S, Lahelma E. Smoking and SF-36 health functioning. Preventive Medicine 2006;42:206-9. Impact factor 2.192 Laaksonen M, Sarlio-Lähteenkorva S, Leino-Arjas P, Martikainen P, Lahelma E. Body weight and health status. Importance of socioeconomic position and working conditions. Obesity Research 2005;13:12:2169-77. Impact factor 3.972 Laamanen R, Øvretveit J, Sundell J, Simonsen-Rehn N, Suominen S, Brommels M. Client perceptions of the performance of public and independent not-for-profit primary healthcare. Scandinavian Journal of Public Health 2006;34:598-608. Impact facto 0.727 Laatikainen T, Pietinen P, Valsta L, Sundvall J, Reinivuo H, Tuomilehto J. Sodium in the Finnish diet: 20-year trends in urinary sodium excretion among the adult population. European Journal of Clinical Nutrition 2006;60:965-70. Impact factor 2.163 Lahelma E. Health inequalities the need for explanation and intervention. Eur J Public Health 2006 Aug;16:4:339. Impact factor 1.118 Lahelma E, Laaksonen M, Martikainen P, Rahkonen O, Sarlio-Lähteenkorva S. Multiple measures of socioeconomic circumstances and common mental disorders. Social Science & Medicine 2006;63:5:1383-99. Impact factor 2.619 Lahelma E, Martikainen P, Rahkonen O, Roos E, Saastamoinen P. Occupational class inequalities across key domains of health: Results from the Helsinki Health Study. European Journal of Public Health 2006;15:5:504-10. Impact factor 1.118 13

Laiho M, Laamanen R, Mussalo-Rauhamaa H, Suominen S. Viranhaltijoiden näkemyksiä resursseista, ennaltaehkäisevästä työstä ja laadusta paikallistason ympäristöterveydenhuollossa. Kunnallistieteellinen aikakauskirja 2006;2:151-168. Laitinen K, Agthe N, Saunamäki R, Fellman M, Henriksson E. Uuden käsidesinfektioaineen tehon tutkimus Kanta-Hämeen keskussairaalan osastolla. Suomen sairaalahygienialehti 2006;24:54-60. Laitinen MH, Ngandu T, Rovio S, Helkala E-L, Uusitalo U, Viitanen M, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. Fat intake at midlife and risk of dementia and Alzheimer s disease: A population-based study. Dementia and Geriatric Cognitive Disorders 2006;22:99-107. Impact factor 2.603 Lallukka T, Martikainen P, Reunanen A, Roos E, Sarlio-Lähteenkorva S, Lahelma E. Associations between working conditions and angina pectoris symptoms among employed women. Psychosomatic Medicine 2006;68:2:348-54. Impact factor 3.642 Lallukka T, Laaksonen M, Rahkonen O, Roos E, Lahelma E. Multiple socioeconomic circumstances and healthy food habits. European Journal of Clinical Nutrition 2006;1-10. Impact factor 2.163 Lavikainen H, Koskinen S, Aro H, Kestilä L, Lyytinen H, Martelin T, Pensola T, Rahkonen O, Aromaa A. Kouluvaikeuksien yleisyys ja yhteydet aikuisiän elämäntilanteeseen ja koettuun terveyteen. Yhteiskuntapolitiikka 2006;71:4:402-10. Lee D-H, Silventoinen K, Hu G, Jacobs Jr DR, Jousilahti P, Sundvall J, Tuomilehto J. Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28 838 middle-aged men and women. European Heart Journal 2006;27:2170-6. Impact factor 7.341 Leiter LA, Ceriello A, Davidson JA, Hanefeld M, Monnier L, Owens DR, Tajima N, Tuomilehto J, for the International Prandial Glucose Regulation Study Group. Postprandial glucose regulation: New data and new implications. Clinical Therapeutics 2005; 27:supp. B:S42-S55. Impact factor 3.030 Lindfors PM, Nurmi KE, Meretoja OA, Luukkonen RA, Viljanen A-M, Leino TJ, Härmä MI. On-call stress among Finnish anaesthetists. Anaesthesia 2006;61:856-66. Impact factor 2.512 Lindström J, Ilanne-Parikka P, Peltonen M, Aunola S, Eriksson JG, Hemiö K, Hämäläinen H, Härkönen P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Mannelin M, Paturi M, Sundvall J, Valle TT, Uusitupa M, Tuomilehto J, on behalf of the Finnish Diabetes Prevention Study Group. Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study. Lancet 2006;368:1673-9. Impact factor 23.878 Lindström J, Peltonen M, Eriksson JG, Louheranta A, Fogelholm M, Uusitupa M, Tuomilehto J. High-fibre, low-fat diet predicts long-term weight loss and 14

decreased type 2 diabetes risk: the Finnish Diabetes Prevention Study. Diabetologia 2006;49:912-20. Impact factor 5.337 Louhiala P, Hänninen J. Eutanasia ja itsemäärämisoikeus. Kuoleman hoidettavuus valtaa alaa eutanasialta. Duodecim 2006;122:2060-1. Louhiala P, Hilden H-M. Attitudes of Finnish doctors towards euthanasia in 1993 and 2003. J Med Ethics 2006;32:627-8. Impact factor 1.312 Mager U, Kolehmainen M, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto JO, Pulkkinen L, Uusitupa MI, Finnish Diabetes Prevention Study. Association between Ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance. American Journal of Hypertension 2006;19:9:920-6. Impact factor 3.496 Mager U, Lindi V, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilane- Parikka P, Keinänen-Kiukkaanniemi S, Tuomilehto J, Laakso M, Pulkkinen L, Uusitupa M, for the Finnish Diabetes Prevention Study Group. Association of the Leu72Met polymorphism of the ghrelin gene with the risk of type3 2 diabetes in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study. Diabet Med 2006;23:685-9. Impact factor 2.725 Malmström K, Pitkäranta A, Carpen O, Pelkonen A, Malmberg LP, Turpeinen M, Kajosaari M, Sarna S, Lindahl H, Haahtela T, Mäkelä MJ. Human rhinovirus in bronchial epithelium of infants with recurrent respiratory symptoms. J Allergy Clin Immunol 2006;118:3:591-6. Impact factor 7.667 Matz K, Keresztes K, Tatschl C, Nowotny M, Dachenhausenm A, Brainin M, Tuomilehto J. Disorders of glucose metabolism in acute stroke patients: and underrecognized problem. Diabetes Care 2006;29:4:792-7. Impact factor 7.844 Mikkelsson L, Kaprio J, Kautiainen H, Kujala U, Mikkelsson M, Nupponen H. School fitness tests as predictors of adult health-related fitness. American Journal of Human Biology 2006;18:3:342-9. Impact factor 1.489 Mikkelsson LO, Nupponen H, Kaprio J, Kautiainen H, Mikkelsson M, Kujala UM. Adolescent flexibility, endurance strength, and physical activity as predictors of adult tension neck, low back pain, and knee injury: a 25 year follow up study. Br J Sports Med 2006;40:107-13. Impact factor 1.855 Mäkinen T, Laaksonen M, Lahelma E, Rahkonen O. Associations of childhood circumstances with physical and mental functioning in adulthood. Social Science & Medicine 2006;62:8:1831-9. Impact factor 2.619 Mäkinen T, Laaksonen M, Lahelma E, Rahkonen O. Lapsuuden olosuhteet ja aikuisuuden toimintakyky. Sosiaalilääketieteellinen aikakauslehti 2006;43:3-12. Nakagami T, Qiao Q, Tuomilehto J, Balkau B, Tajima N, Hu G, Borch-Johnsen K. Screen-detected diabetes, hypertension and hypercholesterolemia as predictors of 15

cardiovascular mortality in five populations of Asian origin: the DECODA study. Eur J Cardiovasc Prev Rehabil 2006; Aug 13:4:555-61. Impact factor 2.333 Nan H, Dong Y, Gao W, Tuomilehto J, Qiao Q. Diabetes associated with a low serum uric acid level in a general Chinese population. Diabetes Res Clin Pract 2007:jul:33:7:68-74. Impact factor 1.236 Nan H, Qiao Q, Dong Y, Gao W, Tand B, Qian R, Tuomilehto J. The prevalence of hyperuricemia in a population of the coastal city of Qingdao, China. J Rheumatol 2006; Jul. 33:7:1346-50. Impact factor 3.010 Ngandu T, Helkala E-L, Soininen H, Winblad B, Tuomilehto J, Nissinen A, Kivipelto M. Alcohol drinking and cognitive functions: Findings from the cardiovascular risk factors aging and dementia (CAIDE) study. Dementia and Geriatric Cognitive Disorders 2006;14:23:3:140-9. Impact factor 2.603 Niskanen L, Laaksonen DE, Lindström J, Eriksson JG, Keinänen-Kiukaanniemi S, Ilanne-Parikka P, Aunola S, Hämäläinen H, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. Serum uric acid as a harbinger of metabolic outcome in subjects with impaired glucose tolerance. Diabetes Care 2006;29:709-11. Impact factor 7.844 Ortega-Alonso A, Pedersen NL, Kujala UM, Sipilä S, Törmäkangas T, Kaprio J, Koskenvuo M, Rantanen T. A twin study on the heritability of walking ability among older women. Journal of Gerontology: Medical Sciences 2006;61A:10:1082-5. Impact factor 3.500 Ozaki R, Qiao Q, Wong GWK, Chan MHM, So W-Y, Tong PCY, Ho SCS, Ko GT-C, Kong APS, Lam CWK, Tuomilehto J, Chan JCN. Overweight, family history of diabetes and attending schools of lower academic grading are independent predictors for metabolic syndrome in Hong Kong Chinese adolescents. Arch Dis Child 2006. Impact factor Impact factor 1.787 Paavonen KJ, Swan H, Piippo K, Laitinen P, Fodstad H, Sarna S, Toivonen L, Kontula K, Viitasalo M. beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome. Int J Cardiol 2006;3. Impact factor 1.765 Pagan JL, Rose RJ, Viken RJ, Pulkkinen L, Kaprio J, Dick DM. Genetic and environmental influences on stages of alcohol use across adolescence and into young adulthood. Behavior Genetics 2006;36:4:483-97. Impact factor 1.112 Pajala E, Era P, Koskenvuo M, Kaprio J, Tolvanen A, Rantanen T. Genetic and environmental contribution to postural balance of older women in single and dual task situations. Neurobiol Aging 2006; May 12. Impact factor 5.312 Pajala S, Era P, Koskenvuo M, Kaprio J, Viljanen A, Rantanen T. Genetic factors and susceptibility to falls in older women. Journal of the American Geriatrics Society 2006;54:4:613-8. Impact factor 3.479 16

Palosuo H, Sihto M, Koskinen S, Lahelma E, Prättälä R, Keskimäki I, Manderbacka K. Sosioekonomiset terveyserot ja terveyspolitiikka Suomessa, Ruotsissa, Englannissa ja Hollannissa. Yhteiskuntapolitiikka 2006;71:2:154-66. Peltonen M, Korpi-Hyövälti E, Oksa H, Puolijoki H, Saltevo, Vanhala M, Saaristo T, Saarikoski L, Sundvall J, Tuomilehto J. Lihavuuden, diabeteksen ja muiden glukoosiaineenvaihdunnan häiriöiden esiintyvyys suomalaisessa aikuisväestössä. Dehkon 2D-hanke (D2D). Suomen Lääkärilehti 2006;61:3:163-70. Pesonen E, Andsberg E, Ohlin H, Puolakkainen M, Rautelin H, Sarna S, Persson K. Dual role of infections as risk factors for coronary heart disease. Atherosclerosis 2006;14. Impact factor 3.777 Pietiläinen KH, Bergholm R, Rissanen A, Kaprio J, Häkkinen AM, Sattar N, Yki-Järvinen H. Effects of acquired obesity on endothelial function in monozygotic twins. Obesity 2006;14:5:826-37. Pietiläinen KH, Kannisto K, Korsheninnikova E, Rissanen A, Kaprio J, Ehrenborg E, Hamsten A, Yki-Järvinen H. Acquired obesity increases CD68 and TNF- and decreases adiponectin gene expression in adipose tissue. J Clin Endocrin Metab 2006;91:7:2776-81. Impact factor 6.020 Pitkälä K, Hosia-Randell H, Raivio M, Savikko N, Strandberg T. Vanhuksen lääkehoidon karikoita. Duodecim 2006;122:1503-12. Puig JG, Marre M, Kokot F, Fernandez M, Jermendy G, Opie L, Moyseev V, Scheen A, Ionescu-Tirgoviste C, Saldanha H, Halabe A, Williams B, Mion Jr D, Ruiz M, Hermansen K, Tuomilehto J, Finizola B, Gallois Y, Amouyel P, Ollivier J-P, Asmar R. Efficacy of indapamide SR compared with enalapril in elderly hypertensive patients with type 2 diabetes. AJH 2007;20:09-97. Impact factor 3.496 Pussinen PJ, Alfthan G, Jousilahti P, Paju S, Tuomilehto J. Systemic exposure to Porphyromonas gingivalis predicts incident stroke. Atherosclerosis 2006; Jul 25. Impact factor 3.777 Raevuori A, Keski-Rahkonen A, Bulik CM, Rose RJ, Rissanen A, Kaprio J. Muscle dissatisfaction in young adult men. Clinical Practice and Epidemiology in Mental Health 2006;2:6. Raevuori A, Keski-Rahkonen A, Rose RJ, Rissanen A, Kaprio J. Muscle dissatisfaction and muscle-enhancing substance use: a population-based twin study in young adult men. Twin Res Hum Genet 2006;Jun:9:3:431-7. Impact factor 0.354 Rahkonen O, Laaksonen M, Martikainen P, Roos E, Lahelma E. Job control, job demands, or social class? The impact of working conditions on the relation between social class and health. J Epidemiol Community Health 2006;60:1:50-4. Impact factor 3.003 Rautanen A, Eriksson JG, Andersson S, Osmond C, Tienari P, Sairanen H, Barker DJP, Phillips DIW, Forsén T, Kajantie E. Associations of body size at birth 17

with late-life cortisol concentrations and glucose tolerance are modified by haplotypes of the glucocorticoid receptor gene. The Journal of Clinical Endocrinology & Metabolism 2006;91:11:4544-51. Impact factor 6.020 Read S, Pedersen NL, Gatz M, Berg S, Vuoksimaa E, Malmberg B, Johansson B, McClearn GE. Sex differences after all those years? Heritability of cognitive abilities in old age. Journal of Gerontology: Psychological Sciences 2006;61B:3:P137-43. Impact factor 2.007 Reinivuo H, Valsta LM, Laatikainen T, Tuomilehto J, Pietinen P. Sodium in the Finnish diet: II trends in dietary sodium intake and comparison between intake and 24-h excretion of sodium. European Journal of Clinical Nutrition 2006;60:1160-7. Impact factor 2.163 Roos E, Lahelma E, Rahkonen O. Work-family conflicts and drinking behaviours among employed women and men. Drug and Alcohol Dependence 2006;83:1:49-56. Impact factor 2.969 Ruotsalainen E, Sammalkorpi K, Laine J, Huotari K, Sarna S, Valtonen V, Järvinen A. Clinical manifestations and outcome in Staphylococcus aureus endocarditis among injection drug users and nonaddicts: A prospective study of 74 patients. BMC Infect Dis 2006;6:1:137. Impact factor 1.956 Räsänen P, Krootila K, Sintonen H, Leivo T, Koivisto A-M, Ryynänen O-P, Blom M, Roine RP. Cost-utility of routine cataract surgery. Health and Quality of Life Outcomes 2006;4:74. Räsänen P, Roine E, Sintonen H, Semberg-Konttinen V, Ryynänen P, Roine R. Use of quality-adjusted life years for the estimation of effectiveness of health care: A systematic literature review. International Journal of Technology Assessment in Health Care 2006;22:2:235-41. Impact factor 0.725 Räsänen P, Öhman J, Sintonen H, Ryynänen O-P, Koivisto A-M, Blom M, Roine RP. Cost-utility analysis of routine neurosurgical spinal surgery. J Neurosurg Spine 2006;5:204-9. Impact factor 2.446 Saarni SE, Rissanen A, Sarna S, Koskenvuo M, Kaprio J. Weight cycling of athletes and subsequent weight gain in middle age. International Journal of Obesity 2006;30:11:1639-44. Impact factor 4.482 Saarni SI, Härkänen T, Sintonen H, Suvisaari J, Koskinen S, Aromaa A, Lönnqvist J. The impact of 29 chronic conditions on health-related quality of life: A general population survey in Finland using 15D and EQ-5D. Qual Life Res 2006;8. Impact factor 1.915 Saastamoinen P, Leino-Arjas P, Laaksonen M, Martikainen P, Lahelma E. Pain and health related functioning among employees. J Epidemiol Community Health 2006;60:9:793-8. Impact factor 3.003 18

Salminen M, Sintonen H, Vahlberg T, Isoaho R, Verronen S, Kivelä S-L. Sepelvaltimotautia sairastavien iäkkäiden elämänlaatu. Yleislääkäri 2006;21:1. Salo H, Kilpi T, Sintonen H, Linna M, Peltola V, Heikkinen T. Cost-effectiveness of influenza vaccination of healthy children. Vaccine 2006;Jun 5:24:23:4934-41. Impact factor 2.822 Salomaa-Räsänen A, Kosunen TU, Karjalainen J, Aromaa A, Knekt P, Sarna S, Rautelin H. IgA antibodies in persisting Helicobacter pylori infection in Finnish adults. Clin Microbiol Infect 2006;12:236-40. Impact factor 2.679 Sarlio-Lähteenkorva S. Laatua lihavuuden ehkäisyyn. Pääkirjoitus. Suomen Lääkärilehti 2006;61:41:4201. Sarlio-Lähteenkorva S, Lissau I, Lahelma E. The social patterning of relative body weight and obesity in Denmark and Finland. European Journal of Public Health 2006;16:1:36-40. Impact factor 1.118 Sarlio-Lähteenkorva S, Silventoinen K, Lahti-Koski M, Laatikainen T, Jousilahti P. Socio-economic status and abdominal obesity among Finnish adults from 1992 to 2002. International Journal of Obesity 2006;30:1653-60. Impact factor 4.482 Schönberg-Norio D, Sarna S, Hänninen ML, Katila ML, Kaukoranta SS, Rautelin H. Strain and host characteristics of Campylobacter jejuni infections in Finland. Clin Microbiol Infect 2006;12:8:754-60. Impact factor 2.679 Scott LJ, Bonnycastle LL, Willer CJ, Spran AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KI, Collins FS, Boehnke M. Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes 2006;55:2649-53. Impact factor 8.028 Seldin MF, Shigeta R, Villoslada P, Selmi C, Tuomilehto J, Silva G, Belmont JW, Klareskog L, Gregersen PK. European population substructure: Clustering of Northern and Southern populations. PLOS Genetics 2006;2:9:1339-51. Impact factor - Seppänen J, Heinävaara S, Anttila A, Sarkeala T, Virkkunen H, Hakulinen T. Effects of different phases of an invitational screening program on breast cancer incidence. Int J Cancer 2006;119:920-4. Impact factor 4.700 Shtir C, Nagakawa SI, Duren WL, Conneely KN, Scott LJ, Silander K, Valle TT, Tuomilehto J, Buchanan TA, Bergman RN, Collins FS, Boehnke M, Watanabe RM. Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q. Human Heredity 2007;63:17-25. Impact factor 3.645 Sihvola E, Keski-Rahkonen A, Dick DM, Pulkkinen L, Rose RJ, Marttunen M, 19

Kaprio J. Minor depression in adolescence: Phenomenology and clinical correlates. J Affect Disord 2007;97:211-8. Impact factor 3.078 Siitonen N, Pulkkinen L, Mager U, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, for the Finnish Diabetes Prevention Study Group. Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study. Journal of Diabetologia 2006;49:8:1795-805. Impact factor 5.337 Silventoinen K, Zdravkovic S, Skytthe A, McCarron P, Herskind AM, Koskenvuo M, de Flaire U, Pedersen N, Christensen K, Kaprio J, for the GenomEUtwin Project. Association between height and coronary heart disease mortality: A prospective study of 35,000 twin pairs. American Journal of Epidemiology 2006;163:7:615-21. Impact factor 5.068 Silventoinen K, Posthuma D, Lahelma E, Rose RJ, Kaprio J. Genetic and environmental factors affecting self-rated health from age 16-25: A longitudinal study of Finnish Twins. Behav Genet 2006;12. Impact factor 3.171 Silventoinen K, Posthuma D, van Beijsterveldt T, Bartels M, Boomsma DI. Genetic contributions to the association between height and intelligence: evidence form Dutch twin data from childhood to middle age. Genes, Brain and Behavior 2006;5:8:585-95. Impact factor 4.091 Simonsen-Rehn N, Øvretveit J, Laamanen R, Suominen S, Sundell J, Brommels M. Determinants of health promotion action: comparative analysis of local voluntary associations in four municipalities in Finland. Health Promot Int 2006;21:4:274-83. Impact factor 1.159 Strandberg TE, Sak K, Soots A, Pitkälä KH, Sintonen H, Huusko T, Tilvis RS. Kotona asuvien kaupunkilaisvanhusten terveys ja elämänlaatu Tallinassa ja Helsingissä. Suomen Lääkärilehti 2006;61:14:1615-9. Stubbe JH, Boomsma DI, Vink JM, Cornes BK, Martin NG, Skytthe A, Kyvik KO, Rose RJ, Kujala UM, Kaprio J, Harris JR, Pedersen NL, Hunkin J, Spector TD, de Geus EJC. Genetic influences on exercise participation in 37.051 twin pairs from seven countries. Plos One 2006;1:e22:1-7. Sulander T, Martelin T, Sainio P, Rahkonen O, Nissinen A, Uutela A. Trends and educational disparities in functional capacity among people aged 65-84 years. Int J Epidemiol 2006;35:1255-61. Impact factor 4.045 Sulander T, Rahkonen O, Nissinen A, Uutela A. Association of smoking status with obesity and diabetes among elderly people. Archive of Gerontology and Geriatrics 2006. Impact factor 0.760 Suviolahti E, Reue K, Cantor RM, Phan J, Gentile M, Naukkarinen J, Soro- Paavonen A, Oksanen L, Kaprio J, Rissanen A, Salomaa V, Kontula K, Taskinen M-R, Pajukanta P, Peltonen L. Cross-species analyses implicate Lipin 1 20

involvement in human glucose metabolism. Human Molecular Genetics 2006;15:3:377-86. Impact factor 7.764 Särkijärvi S, Kuusisto H, Paalavuo R, Levula M, Airla N, Lehtimäki T, Kaprio J, Koskenvuo M, Elovaara I. Gene expression profiles in Finnish twins with multiple sclerosis. BMC Medical Genetics 2006;7:11. Tapp RJ, Zimmet PZ, Harper CA, McCarty DJ, Chitson P, Tonkin AM, Söderberg S, Taylor HR, Alberti KGMM, Tuomilehto J, Shaw JE. Six year incidence and progression of diabetic retinopathy: Results from the Mauritius diabetes complication study. Diabetes Research and Clinical Practice 2006:73:298-303. Impact factor 1.236 Tiainen K, Pajala S, Sipilä S, Kaprio J, Koskenvuo M, Alen M, Heikkinen E, Tolvanen A, Rantanen T. Genetic effects in common on maximal walking speed and muscle performance in older women. Scand J Med Sci Sport 2006 (in press). Torppa M. Perusterveydenhuollon täydennyskoulutuksen kehittäminen Espoossa. Duodecim 2006;122:571-7. Torppa MA, Timonen O, Keinänen-Kiukaanniemi S, Larivaara P, Leiman M. Patient-nurse-doctor interaction in general practice teleconsultations a qualitative analysis. Journal of Telemedicine and Telecare 2006;12:306-10. Impact factor 0.749 Tulamo R, Frösen J, Junnikkala S, Paetau A, Pitkäniemi J, Kangasniemi M, Niemelä M, Jääskeläinen J, Jokitalo E, Karatas A, Hernesniemi J, Meri S. Complement activation associates with saccular cerebral artery aneurysm wall degeneration and rupture. Neurosurgery 2006;59:5. Impact factor 2.587 Tuomilehto J. Modeling of primary prevention of the development of type 2 diabetes. Przegl Lek 2006;63:Suppl 4:3-6. Tuomilehto J, Gao W, Qiao Q. Assessing the preprandial glucose target: 100 mg/dl versus 110 mg/dl. Endocrine Practice 2006;12:supp.1:67-70. Tuominen U, Blom M, Hirvonen J, Seitsalo S, Paavolainen P, Lehto MUK, Hietaniemi K, Rissanen P, Sintonen H. Millainen vaikutus lisäsairauksilla on lonkan tekonivelleikkaukseen jonottavien potilaiden elämänlaatuun? Suomen Ortopedia ja traumatologia 2006;29:354-7 Utriainen I, Sarlio-Lähteenkorva S, Aittomäki A, Lahelma E. Keski-ikäisten painoindeksi ja keskivartalolihavuus Selvitys Helsingin kaupungin henkilöstön terveystutkimusaineistosta. Suomen Lääkärilehti 2006;61:5:419-22. Uusitupa M, Tuomilehto J. Tyypin 2 diabetes on ehkäistävissä, ja niksit ovat tiedossa. Duodecim 2006;122:2675-6. Wang JJ, Li HB, Kinnunen L, Hu G, Järvinen TM, Miettinen ME, Yuan S, Tuomilehto J. How well does the metabolic syndrome defined by five definitions 21