Isometsä, Erkki Tapio LIST OF PUBLICATIONS

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1 Isometsä, Erkki Tapio LIST OF PUBLICATIONS Overall 335 scientific publications; 209 original papers & 117 reviews, editorials, or textbook chapters. Cited times, h-index 47 (Web of Science). I PEER-REVIEWED SCIENTIFIC ARTICLES 1.1 Original publications [IF/journal ranking in 2014] 1. Isometsä E, Henriksson M, Lönnqvist J: Completed suicide and recent lithium treatment. Journal of Affective Disorders 1992;26: [3.383;44./140] 2. Spoov J, Suominen JY, Lahdelma RL, Katila H, Kymäläinen O, Isometsä E, Liukko H, Auvinen J. Do reversed depressive symptoms occur together as a syndrome? Journal of Affective Disorders 1993;27: [3.383;44./140] 3. Lönnqvist J, Aro H, Marttunen M, Henriksson M, Isometsä E, Kuoppasalmi K, Huurre T. Hoitojärjestelmä ja itsemurha. In: J Lönnqvist, H Aro, M Marttunen, eds. Itsemurhat Suomessa 1987-projekti.Toteutus, aineisto ja tutkimustuloksia. STAKESin tutkimuksia 25/93. Jyväskylä, Gummerus, 1993: Henriksson MM, Aro HM, Marttunen MJ, Heikkinen ME, Isometsä ET, Kuoppasalmi KI, Lönnqvist JK: Mental disorders and comorbidity in suicide. American Journal of Psychiatry 1993;150: [14.721;4./140] 5. Isometsä E, Henriksson M, Heikkinen M, Lönnqvist J. Suicide after discharge from psychiatric inpatient care (letter). Lancet 1993;342: [45.217;2./153] 6. Isometsä ET, Henriksson MM, Aro HM, Heikkinen ME, Kuoppasalmi KK, Lönnqvist JK. Suicide in major depression. American Journal of Psychiatry 1994;151: [14.721;4./140] 7. Isometsä ET, Henriksson MM, Aro HM, Lönnqvist JK. Suicide in bipolar disorder in Finland. American Journal of Psychiatry 1994;151: [14.721;4./140] 8. Isometsä E, Henriksson M, Aro H, Heikkinen M, Kuoppasalmi K, Lönnqvist J: Suicide in psychotic major depression. Journal of Affective Disorders 1994;31: [3.383;44./140] 9. Isometsä ET, Aro HM, Henriksson MM, Heikkinen ME, Lönnqvist JK: Suicide in major depression in different treatment settings. Journal of Clinical Psychiatry 1994;55: [5.498;18./140] 10. Heikkinen M, Aro H, Henriksson M, Isometsä E, Sarna S, Kuoppasalmi K, Lönnqvist J: Differences in recent life events between alcoholic and depressive nonalcoholic suicides. Alcoholism: Clinical and Experimental Research 1994;18: [3.205;5./19] 11. Henriksson MM, Marttunen MJ, Isometsä ET, Heikkinen ME, Aro HM, Kuoppasalmi KI, Lönnqvist JK. Mental disorders in elderly suicide. International Psychogeriatrics 1995;7: (Reproduced with permission in: Suicide and Aging. International Perspectives. JL Pearson, Y Conwell, eds. New York, Springer Publishing Company,1997, pp ) [1.934;78./140 ]

2 12. Isometsä E, Heikkinen M, Henriksson M, Aro H, Lönnqvist J. Recent life events and completed suicide in bipolar affective disorder. A comparison with major depressive suicides. Journal of Affective Disorders 1995;33: [3.383;44./140] 13. Heikkinen ME, Isometsä ET, Aro HM, Sarna SJ, Lönnqvist JK. Age-related variation in recent life events preceding suicide. Journal of Nervous and Mental Disease 1995;183: [1.688;89./140] 14. Isometsä ET, Heikkinen ME, Marttunen MJ, Henriksson MM, Aro HM, Lönnqvist JK. The last appointment before suicide: Is suicidal intent communicated? American Journal of Psychiatry 1995;152: [14.721;4./140] 15. Marttunen MJ, Aro HM, Henriksson MM, Heikkinen ME, Isometsä ET, Lönnqvist JK. Suicide among adolescent females. Characteristics of victims in the age group years. Journal of the American Academy of Child and Adolescent Psychiatry 1995;34: [7.26;10./140] 16. Isometsä E, Henriksson M, Marttunen M, Heikkinen M, Aro H, Kuoppasalmi K, Lönnqvist J. Mental disorders in young and middle-aged men who commit suicide. BMJ-British Medical Journal 1995;310: [17.445;5./153] 17. Heikkinen ME, Isometsä ET, Marttunen MJ, Aro HM, Lönnqvist JK. Social factors in suicide. British Journal of Psychiatry 1995;167: [7.991;9./140] 18. Henriksson MM, Isometsä ET, Hietanen PS, Aro HM, Lönnqvist JK. Mental disorder in cancer suicides. Journal of Affective Disorders 1995;36:11-20.[3.383; 44./140] 19. Isometsä E, Heikkinen M, Henriksson M, Aro H, Marttunen M, Kuoppasalmi K,Lönnqvist J. Suicide in non-major depressions. Journal of Affective Disorders 1996;36: [3.383;44./140] 20. Isometsä ET, Henriksson MM, Heikkinen ME, Aro HM, Marttunen MJ, Kuoppasalmi KI, Lönnqvist JK. Suicide among subjects with personality disorders. American Journal of Psychiatry 1996;153: [14.721;4./140] 21. Isometsä ET, Henriksson MM, Heikkinen ME, Lönnqvist JK. Completed suicide and recent electroconvulsive therapy in Finland. Convulsive Therapy 1996;12: [Currently: Journal of ECT, 1.389; 97./140] 22. Suominen K, Henriksson M, Suokas J, Isometsä E, Ostamo A, Lönnqvist J. Mental disorders and comorbidity in attempted suicide. Acta Psychiatrica Scandinavica. 1996;94: [5.605; 17./140] 23. Henriksson MM, Isometsä ET, Kuoppasalmi KI, Heikkinen ME, Marttunen MJ, Lönnqvist JK. Panic disorder in completed suicide. Journal of Clinical Psychiatry 1996;57: [5.498;18./140] 24. Isometsä ET, Heikkinen ME, Henriksson MM, Aro HM, Marttunen MJ, Lönnqvist JK. Parenthood, completed suicide and mental disorders (letter). Archives of General Psychiatry 1996;53: [14.48;2./140] 25. Heikkinen ME, Isometsä ET, Henriksson MM, Marttunen MJ, Aro HM, Lönnqvist JK. Psychosocial factors and completed suicide in personality disorders. Acta Psychiatrica 2

3 Scandinavica 1997;95:49-57.[5.605;17./140] 26. Isometsä ET, Henriksson MM, Heikkinen ME, Aro HM, Marttunen MJ, Lönnqvist JK. Differences between urban and rural suicides. Acta Psychiatrica Scandinavica 1997;95: [5.605;17./140] 27. Heikkinen ME, Henriksson MM, Isometsä ET, Aro HM, Marttunen MJ, Kuoppasalmi KI, Lönnqvist JK. Life events and suicide in personality disorders. Journal of Nervous and Mental Disease 1997;185: [1.688;89./140] 28. Isometsä E, Aro S, Aro H. Depression in Finland: A Computer Assisted Telephone Interview study. Acta Psychiatrica Scandinavica 1997;96: [5.605;17./140] 29. Suominen K, Isometsä E, Henriksson M, Ostamo A, Lönnqvist J. Differences in hopelessness, suicide intent and impulsivity among suicide attempters with major depression, alcohol dependence or both. Acta Psychiatrica Scandinavica 1997;96: [5.605;17./140] 30. Heilä H, Isometsä ET, Henriksson MM, Heikkinen ME, Marttunen MJ, Lönnqvist JK. Suicide and schizophrenia.a nationwide psychological autopsy study on age- and sexspecific clinical characteristics of 92 suicide victims with schizophrenia. American Journal of Psychiatry 1997;154: [14.721;4./140] 31. Pirkola S, Isometsä E, Heikkinen M, Lönnqvist J. Employment status influences the weekly pattern of suicide among alcohol misusers. Alcoholism-Clinical and Experimental Research 1997;21: [3.205;5./19] 32. Marttunen M, Henriksson M, Aro H, Heikkinen M, Isometsä E, Lönnqvist J. Gender differences in adolescent suicide. In: Suicide Prevention: A Holistic Approach. D De Leo, A. Schmidtke and R.F.W. Diekstra, editors.boston, Kluwer Academy Press, 1998: Marttunen MJ, Henriksson MM, Isometsä ET, Heikkinen ME, Aro HM, Lönnqvist JK. Completed suicide among adolescents with no diagnosable psychiatric disorder. Adolescence 1998;33: [0.639; 59./67 in 2011, IF 2014 unknown ] 34. Isometsä E, Seppälä I, Henriksson M, Kekki P, Lönnqvist J. Inadequate dosaging in general practice of tricyclic vs. other antidepressants for depression. Acta Psychiatrica Scandinavica 1998;98: [5.605;17./140] 35. Suominen K, Isometsä ET, Henriksson MM, Ostamo A, Lönnqvist JK. Inadequacy of treatment received for major depression both before and after a suicide attempt. American Journal of Psychiatry 1998;155: [14.721;4./140] 36. Heilä H, Isometsä ET, Henriksson MM, Heikkinen ME, Marttunen MJ, Lönnqvist JK. Antecedents of suicide in people with schizophrenia. British Journal of Psychiatry 1998;173: [7.991;9./140] 37. Isometsä ET, Lönnqvist JK. Suicide attempts preceding completed suicide. British Journal of Psychiatry 1998;173: [7.991;9./140] 38. Pitkälä K, Isometsä E, Henriksson M, Lönnqvist J. Iäkkäiden itsemurhat Suomessa [Elderly suicide in Finland]. Duodecim 1999;115:

4 39. Pirkola S, Isometsä E, Henriksson M, Heikkinen M, Marttunen M, Lönnqvist J. Female psychoactive substance dependent suicides differ from male. Comprehensive Psychiatry 1999;40: [2.252;69./140] 40. Pirkola S, Isometsä E, Henriksson M, Heikkinen M, Marttunen M, Lönnqvist J. The treatment received by substance dependent male and female suicide victims. Acta Psychiatrica Scandinavica 1999;99: [5.605;17./140] 41. Suominen K, Isometsä E, Henriksson M, Ostamo A, Lönnqvist J. Treatment received by alcohol dependent suicide attempters. Acta Psychiatrica Scandinavica 1999;99: [5.605;17./140] 42. Heilä H, Isometsä ET, Henriksson MM, Heikkinen ME, Marttunen MJ, Lönnqvist JK. Suicide victims with schizophrenia in different treatment phases and the adequacy of antipsychotic medication. Journal of Clinical Psychiatry 1999;60: [5.498;18./140] 43. Heilä H, Heikkinen ME, Isometsä ET, Henriksson MM, Marttunen MJ, Lönnqvist JK. Life events and completed suicide in schizophrenia. A comparison of suicide victims with and without schizophrenia.schizophrenia Bulletin 1999;3: [8.45;8./140] 44. Suominen K, Isometsä E, Henriksson M, Suokas J, Ostamo A, Lönnqvist J. Consultation vs. research diagnoses of mental disorders among suicide attempters. Nordic Journal of Psychiatry 1999;53: [1.339;100./140] 45. Lindeman S, Henriksson M, Isometsä E, Lönnqvist J. Treatment of mental disorders in seven physicians committing suicide. Crisis 1999;20:86-89.[1.482;47./129.] 46. Pirkola SP, Marttunen MJ, Henriksson MM, Isometsä ET, Heikkinen ME, Lönnqvist JK. Alcohol-related problems among adolescent suicides in Finland.Alcohol and Alcoholism, 1999;34: [2.889;5./36] 47. Pirkola SP, Isometsä ET, Heikkinen ME, Lönnqvist JK. Suicides of alcohol misusers and nonmisusers in a nationwide population. Alcohol and Alcoholism 2000;35: [2.889;5./36] 48. Pitkälä K, Isometsä E, Henriksson M, Lönnqvist JK. Elderly suicides in Finland. International Psychogeriatrics 2000;12: [1.934;78./140] 49. Lindeman S, Hämäläinen J, Isometsä E, Kaprio J, Poikolainen K, Heikkinen M, Aro H. The 12- month prevalence and risk factors for major depressive episode in Finland: Representative sample of 5993 adults. Acta Psychiatrica Scandinavica 2000;102: [5.605;17./140] 50. Suominen KH, Isometsä ET, Henriksson MM, Ostamo AI, Lönnqvist JK. Suicide attempts and personality disorder. Acta Psychiatrica Scandinavica 2000;102: [5.605;17./140] 51. Isometsä ET, Katila H, Aro T. Disability pension for major depression in Finland. American Journal of Psychiatry 2000;157: [14.721;4./140] 52. Isometsä ET, Katila H, Aro T. Disability pension for major depression in Finland a review and further findings. Psychiatria Fennica 2000;31: Taiminen T, Huttunen J, Heilä H, Henriksson M, Isometsä E, Kähkönen J, Tuominen K, Lönnqvist J, Addington D, Helenius H. The Schizophrenia Suicide Risk Scale (SSRS): development and initial validation. Schizophrenia Research 2001;47: [3.923;30./140] 4

5 54. Suokas J, Suominen K, Isometsä E, Ostamo A, Lönnqvist J. Long-term risk factors for suicide mortality after attempted suicide findings of a 14-year follow-up study. Acta Psychiatrica Scandinavica 2001;104: [5.605;17./140] 55. Hämäläinen J, Kaprio J, Isometsä E, Heikkinen M, Poikolainen K, Lindeman S, Aro H. Cigarette smoking and alcohol intoxication as risk factors for major depressive episode. Journal of Epidemiology and Community Health 2001;55: [3.501;20./162] 56. Rytsälä HJ, Melartin TK, Leskelä U, Lestelä-Mielonen U, Sokero P, Isometsä ET. A record based investigation of 803 patients treated for depression in psychiatric care. Journal of Clinical Psychiatry 2001;62: [5.498;18./140] 57. Laukkala T, Isometsä E, Hämäläinen J, Heikkinen M, Lindeman S, Aro H. Antidepressant treatment of depression in the Finnish general population. American Journal of Psychiatry 2001;158: [14.721;4./140] 58. Lindeman S, Kaprio J, Isometsä E, Poikolainen K, Heikkinen M, Hämäläinen J, Haarasilta L, Laukkala T, Aro H. Spousal resemblance for history of major depressive episode in the last year. Psychological Medicine 2002;32: [5.938;14./140] 59. Suominen KH, Isometsä ET, Ostamo AI, Lönnqvist JK. Health care contacts before and after attempted suicide. Social Psychiatry and Psychiatric Epidemiology 2002;37: [2.537;60./140] 60. Melartin TK, Rytsälä HJ, Leskelä US, Lestelä-Mielonen PS, Sokero TP, Isometsä ET. Current comorbidity of psychiatric disorders among DSM-IV major depressive disorder patients in psychiatric care in the Vantaa Depression Study. Journal of Clinical Psychiatry 2002;63: [5.498;18./140] 61. Pynnönen PA, Isometsä ET, Verkasalo MA, Savilahti E, Aalberg VA. Untreated celiac disease and development of mental disorders in children and adolescents. Psychosomatics 2002;43:331-4.[1.858;82./140] 62. Pynnönen P, Isometsä ET, Aalberg V, Verkasalo M, Savilahti E. Is coeliac disease prevalent among adolescent psychiatric patients? Acta Paediatrica 2002;91: [1.688;51./119] 63. Pirkola S, Lönnqvist J ja mielenterveyden työryhmä (Kirsi Ahola, Martti Heikkinen, Teija Honkonen, Erkki Isometsä, Matti Joukamaa, Raija Kalimo, Olli Kiviruusu, Teemu Kärnä, Eero Lahtinen, Ville Lehtinen, Kari Poikolainen, Raimo Raitasalo, Jouko Salminen, Jaana Suvisaari). Psyykkinen oireilu ja mielenterveyden häiriöt. In: Terveys ja toimintakyky Suomessa. Terveys 2000-tutkimuksen perustulokset. Arpo Aromaa, Seppo Koskinen, eds. Publications of the National Public Health Institute, B3/2002, pp Suominen KH, Isometsä ET, Lönnqvist JK. Comorbid substance use reduces the health care contacts of suicide attempters with schizophrenia spectrum or mood disorders. Schizophrenia Bulletin 2002;28: [8.45;8./140] 65. Suominen K, Isometsä E, Lönnqvist J, Heilä H, Henriksson M. General hospital suicides a psychological autopsy study in Finland. General Hospital Psychiatry 2002;24: [2.606;58./140] 5

6 66. Partonen T, Haukka J, Viilo K, Hakko H, Pirkola S, Isometsä E, Lönnqvist J, Särkioja T, Väisänen E, Räsänen P. Cyclic time patterns of death from suicide in Northern Finland. Journal of Affective Disorders 2004;78:11-19.[3.383;44./140] 67. Hämäläinen J, Isometsä E, Laukkala T, Kaprio J, Poikolainen K, Heikkinen M, Lindeman S, Aro H, Use of health services for major depressive episode in Finland. Journal of Affective Disorders 2004;79: [3.383;44./140] 68. Vuorilehto M, Isometsä E, Ihalainen R, Korhonen A. Masennus, ahdistuneisuus ja alkoholin riskikäyttö terveyskeskuspotilailla. Suomen Lääkärilehti 2003;58: [Mental symptoms among unselected users of primary health care. Journal of the Finnish Medical Association. In Finnish]. 69. Vuorilehto M, Isometsä E. Terveyskeskuksen konsultoivan psykiatrin potilaiden mielenterveyden häiriöt. Suomen Lääkärilehti 2003;58: [Mental symptoms and disorders among primary care patients referred to psychiatric consultation. Journal of the Finnish Medical Association.In Finnish] 70. Sokero P, Melartin T, Rytsälä H, Leskelä U, Lestelä-Mielonen P, Isometsä ET. Suicidal ideation and attempts among psychiatric patients with major depressive disorder. Journal of Clinical Psychiatry 2003;64: [5.498;18./140] 71. Pirkola S, Isometsä E, Lönnqvist J. Do means matter? Journal of Nervous and Mental Disease 2003;191: [1.688;89./140] 72. Suominen K, Isometsä E, Marttunen M, Ostamo A, Lönnqvist J. Health care contacts before and after attempted suicide among adolescent and young adult vs. older suicide attempters. Psychological Medicine 2004;34: [5.938;14./140] 73. Suominen K, Isometsä E, Henriksson M, Ostamo A, Lönnqvist J. The patients' evaluation of their psychiatric consultation after attempted suicide. Nordic Journal of Psychiatry 2004;58:55-59.[1.339;100./140] 74. Isometsä E, Suominen K, Mantere O, Valtonen H, Leppämäki S, Pippingsköld M, Arvilommi P. The Mood Disorder Questionnaire improves recognition of bipolar disorder in psychiatric care. BMC Psychiatry 2003;3:8.[2.21;71./140] 75. Partonen T, Haukka J, Pirkola S, Isometsä E, Lönnqvist J. Time patterns and seasonal mismatch in suicide. Acta Psychiatrica Scandinavica 2004;109: [5.605;17./140] 76. Suominen K, Isometsä E, Suokas J, Haukka J, Achte K, Lönnqvist J. Completed suicide after a suicide attempt: a 37-year follow-up study. American Journal of Psychiatry 2004;161: [14.721;4./140] 77. Suominen K, Henriksson M, Isometsä E, Conwell Y, Heilä H, Lönnqvist J. Nursing home suicides a psychological autopsy study. International Journal of Geriatric Psychiatry 2003;18: [3.13;52./140] 78. Leskelä U, Melartin T, Lestelä-Mielonen P, Rytsälä H, Sokero P, Isometsä E. Life events, social support and the onset of major depressive disorder in Finnish patients. Journal of Nervous and Mental Disease 2004;192: [1.688;89./140] 6

7 79. Suominen K, Isometsä E, Lönnqvist J. Elderly suicide attempters with depression are often diagnosed only after the attempt. International Journal of Geriatric Psychiatry 2004;19:35-40.[3.13;52./140] 80. Pallaskorpi S, Isometsä E, Henriksson M, Suominen K, Lönnqvist J. Yksilöpsykoterapian aikana tapahtuneet itsemurhat Suomessa Suicides during psychotherapy in Finland]. Duodecim 2004;120: Melartin T, Rytsälä H, Leskelä U, Lestelä-Mielonen, Sokero P, Isometsä E. Severity and comorbidity predict episode duration and recurrence of DSM-IV major depressive disorder. Journal of Clinical Psychiatry 2004;65: [5.498;18./140] 82. Suominen KH, Isometsä ET, Lönnqvist JK. Attempted suicide and psychiatric consultation. European Psychiatry 2004;19: [3.439;40./140] 83. Palmu R, Isometsä E, Suominen K, Vuola J, Leppävuori A, Lönnqvist J. Self-inflicted burns: An eight-year retrospective study in Finland. Burns 2004;30: [1.88;80./198] 84. Pynnönen PA, Isometsä ET, Aronen ET, Verkasalo MA, Savilahti E, Aalberg VA. Mental disorders in adolescents with celiac disease. Psychosomatics 2004;45: [1.858;82./140] 85. Suominen K, Isometsä E, Haukka J, Lönnqvist J. Substance use and male gender as risk factors for death and suicide: a five-year follow-up study after attempted suicide. Social Psychiatry and Psychiatric Epidemiology 2004;39: [2.537;60./140] 86. Melartin T, Leskelä U, Rytsälä H, Sokero P, Lestelä-Mielonen P, Isometsä E. Comorbidity and stability of melancholic features in DSM-IV major depressive disorder. Psychological Medicine 2004;34: [5.938;14./140] 87. Suominen K, Isometsä E, Ostamo A, Lönnqvist J. Level of suicidal intent predicts overall mortality and suicide after attempted suicide: A 12-year follow-up study. BMC Psychiatry 2004;4:11.[2.21;71./140] 88. Rytsälä HJ, Melartin TK, Leskelä US, Sokero TP, Lestelä-Mielonen PS, Isometsä ET. Functional and work disability in major depressive disorder in Finnish patients. Journal of Nervous and Mental Disease 2005;193: [1.688;89./140] 89. Pirkola S, Isometsä E, Suvisaari J, Aro H, Joukamaa M, Poikolainen K, Koskinen S, Aromaa A, Lönnqvist J. DSM-IV mood-, anxiety and alcohol use disorders and their comorbidity in the Finnish general population. Results from the Health 2000 Study. Social Psychiatry and Psychiatric Epidemiology 2005;40:1-10.[2.537;60./140] 90. Mantere O, Suominen K, Leppämäki S, Valtonen H, Arvilommi P, Isometsä E. The clinical characteristics of DSM-IV bipolar I and II disorders: baseline findings from the Jorvi Bipolar Study (JoBS). Bipolar Disorders 2004;6: [4.965;20./140] 91. Melartin TK, Rytsälä HJ, Leskelä US, Lestelä-Mielonen PS, Sokero TP, Isometsä ET.Continuity is the main challenge in treating major depressive disorder in psychiatric care. Journal of Clinical Psychiatry 2005;66: [5.498;18./140] 92. Vuorilehto M, Melartin T, Isometsä E. Depressive disorders in primary care: Recurrent, chronic and comorbid. Psychological Medicine 2005;35: [5.938;14./140] 7

8 93. Sokero TP, Melartin TK, Rytsälä HJ, Leskelä US, Lestelä-Mielonen PS, Isometsä ET. A prospective study of risk factors for attempted suicide among psychiatric patients with DSM-IV major depressive disorder. British Journal of Psychiatry 2005;186: [7.991;9./140] 94. Hämäläinen J, Poikolainen K, Isometsä E, Kaprio J, Heikkinen M, Lindeman S, Aro H. Major depressive episode related to long unemployment and frequent alcohol intoxication. Nordic Journal of Psychiatry 2005;59: [1.339;100./140] 95. Pynnönen PA, Isometsä ET, Verkasalo M, Kähkönen S, Sipilä I, Savilahti E, Aalberg VA. Glutenfree Diet May Alleviate Depressive and Behavioural Symptoms in Adolescents with Celiac Disease. BMC Psychiatry 2005;5:14.[2.21;71./140] 96. Valtonen H, Suominen K, Mantere O, Leppämäki S, Arvilommi P, Isometsä ET. Suicidal Ideation and Attempts in Bipolar I and II Disorders. Journal of Clinical Psychiatry 2005;66: [5.498;18./140] 97. Pallaskorpi S, Isometsä E, Henriksson M, Suominen K, Lönnqvist J. Completed suicide among subjects receiving psychotherapy. Psychotherapy & Psychosomatics 2005;74: [9.196;5./133] 98. Pirkola S, Isometsä E, Aro H, Kestilä L, Hämäläinen J, Veijola J, Kiviruusu O, Lönnqvist J. Childhood adversities as risk factors for adult mental disorders. Social Psychiatry & Psychiatric Epidemiology 2005;40: [2.537;60./140] 99. Ahola K, Honkonen T, Isometsä E, Kalimo R, Nykyri E, Aromaa A, Lönnqvist J. The relationship between burnout and depressive disorders - Results from the Finnish Health 2000 Study. Journal of Affective Disorders 2005;88:55-62.[3.383;44./140] 100. Jylhä P, Isometsä E. Temperament, character and symptoms of anxiety and depression in the general population. European Psychiatry 2006;21: [3.439;40./140] 101. Linkenkaer-Hansen K, MontoS, Rytsälä H, Suominen K, Isometsä E, Kähkönen S. Breakdown of long-range temporal correlations in theta oscillations in major depressive disorder. Journal of Neuroscience 2005;25: [6.344;24./252] 102. Mantere O, Suominen K, Melartin T, Valtonen H, Arvilommi P, Leppämäki S, Rytsälä H, Isometsä E. Differences in patterns of axis I and II comorbidity of bipolar I vs. II vs. major depressive disorders. Journal of Clinical Psychiatry 2006;67: [5.498;18./140] 103. Vuorilehto M, Melartin T, Isometsa E. Suicidal behaviour among primary care patients with depressive disorders. Psychological Medicine 2006;36: [5.938;14./140] 104. Honkonen T, Ahola K, Pertovaara M, Isometsä E, Kalimo R, Nykyri E, Aromaa A, Lönnqvist J: The association between burnout and physical illness in the general population - Results from the Finnish Health 2000 Study. Journal of Psychosomatic Research 2006;61: [2.736;55./140] 105. Ahola K, Honkonen T, Isometsä E, Kalimo R, Nykyri E, Koskinen S, Aromaa A, Lönnqvist J. Burnout in General Population Results in the Finnish Health 2000 Study. Social Psychiatry & Psychiatric Epidemiology 2006;41:11-17.[2.537;60./140] 8

9 106. Jylhä P, Isometsä E. The relationship of neuroticism and extraversion to symptoms of anxiety and depression in the general population. Depression and Anxiety 2006:23: [4.407;23./140] 107. Leskelä U, Rytsälä H, Melartin T, Komulainen E, Sokero P, Lestelä-Mielonen P, Isometsä E. Is the influence of psychosocial factors on the outcome of major depressive disorder equal for all current levels of depressive symptoms? Psychological Medicine 2006;36: [5.938;14./140] 108. Valtonen H, Suominen K, Mantere O, Leppämäki S, Arvilommi P, Isometsä E. Prospective study of risk factors for attempted suicide among bipolar disorder patients. Bipolar Disorders 2006;8: [4.965;20./140] 109. Fingelkurts AA, Fingelkurts AA, Rytsälä H, Suominen K, Isometsä E, Kähkönen S. Impaired functional connectivity at EEG alpha and theta frequency bands in major depression. Human Brain Mapping 2007;28: [6.924;27./252] 110. Rytsälä HJ, Melartin TK, Leskelä US, Lestelä-Mielonen PS, Sokero TP, Isometsä ET. Determinants of functional disability and social adjustment in major depressive disorder: a prospective study. Journal of Nervous and Mental Disease 2006;194: [1.688;89./140] 111. Perälä J, Suvisaari J, Saarni S, Kuoppasalmi K, Isometsä E, Pirkola S, Partonen T, Tuulio- Henriksson A, Hintikka J, Kieseppä T, Härkänen T, Koskinen S, Lönnqvist J. Lifetime prevalence of psychotic and bipolar I disorders in a general population. Archives of General Psychiatry 2007;64:19-28.[14.48;2./140] 112. Ahola K, Honkonen T, Pirkola S, Isometsä E, Kalimo R, Nykyri E, Aromaa A, Lönnqvist J. Alcohol dependence in relation to burnout among the Finnish working population. Addiction 2006;101: [4.738;2./19] 113. Sokero TP, Eerola MH, Rytsälä HJ, Melartin TK, Leskelä US, Lestelä-Mielonen PS, Isometsä ET. Decline in suicidal ideation among patients with MDD is preceded by decline in depression and hopelessness. Journal of Affective Disorders 2006;95: [3.383;44./140] 114. Sihvo S, Hämäläinen J, Kiviruusu O, Pirkola S, Isometsä E. Treatment of anxiety disorders in the Finnish general population. Journal of Affective Disorders 2006;96:31-8.[3.383;44./140] 115. Valtonen H, Suominen K, Mantere O, Leppämäki S, Arvilommi P, Isometsä E. Suicidal behaviour during different phases of bipolar disorder. Journal of Affective Disorders 2007;97: [3.383;44./140] 116. Rytsälä HJ Melartin TK, Leskelä US, Sokero P, Lestelä-Mielonen PS, Isometsä ET. Predictors of long-term work disability in major depressive disorder: A prospective study. Acta Psychiatrica Scandinavica 2007;115: [5.605;17./140] 117. Arvilommi P, Suominen K, Mantere O, Leppämäki S, Valtonen H, Isometsä ET. Adequacy of treatment received by diagnosed and undiagnosed patients with bipolar I and II disorder. Journal of Clinical Psychiatry 2007;68: [5.498;18./140] 118. Fingelkurts AA, Fingelkurts AA, Rytsälä H, Suominen K, Isometsä E, Kähkönen S. Composition of brain oscillations in ongoing EEG during major depressive disorder. Neuroscience Research 2006;56: [1.937;181./252] 9

10 119. Suominen K, Mantere O, Valtonen H, Arvilommi P, Leppämäki S, Paunio T, Isometsä E. Early age at onset in bipolar disorder is associated with more severe clinical features but delayed treatment seeking. Bipolar Disorders 2007;9: [4.965;20./140] 120. Honkonen T, Virtanen M, Ahola K, Kivimäki M, Pirkola S, Isometsä E, Aromaa A, Lönnqvist J. Employment status, mental disorders and service use in the working age population. Scandinavian Journal of Work, Environment and Health 2007;33:29-36.[3.454;21./162] 121. Hämäläinen J, Sihvo S, Pirkola S, Kiviruusu O, Isometsä E. Use of health services for major depressive and anxiety disorders in Finland. Depression and Anxiety 2008;25: [4.407;23./140] 122. Ahola K, Honkonen T, Kivimäki M, Virtanen M, Isometsä E, Aromaa A, Lönnqvist J. Contribution of burnout to the association between job strain and depression: the Health2000 Study. Journal of Occupational and Environmental Medicine 2006;48: [1.63;85./162] 123. Vuorilehto MS, Melartin TK, Rytsälä HJ, Isometsä ET.Do characteristics of patients with major depressive disorder differ between primary and psychiatric care? Psychological Medicine 2007;37: [5.938;14./140] 124. Kähkönen S, Yamashita H, Rytsälä H, Suominen K, Ahveninen J, Isometsä E. Dysfunction in early auditory processing in major depression disorder revealed by combined MEG and EEG. Journal of Psychiatry & Neuroscience 2007;32: [5.861;29./252] 125. Mantere OK, Suominen KH, Arvilommi PJ, Valtonen H, Leppämäki S, Isometsä ET. Clinical predictors of unrecognised bipolar I and II disorders. Bipolar Disorders 2008;10: [4.965;20./140] 126. Mantere O, Suominen K, Valtonen HM, Arvilommi P, Leppämäki S, Melartin T, Isometsä E. Differences in outcome of DSM-IV bipolar I and II disorders. Bipolar Disorders 2008;10: [4.965;20./140] 127. Valtonen H, Suominen K, Haukka J, Mantere O, Leppämäki S, Arvilommi P, Isometsä E. Differences in incidence of suicide attempts during phases of bipolar I and II disorders. Bipolar Disorders 2008;10: [4.965;20./140] 128. Honkonen TI, Aro T, Isometsä ET, Virtanen M, Katila H. Quality of Treatment and Disability Compensation in Depression: Comparison of 2 nationally representative samples during a 10-year period in Finland. Journal of Clinical Psychiatry 2007;68: [5.498;18./140] 129. Ahola K, Honkonen T, Virtanen M, Isometsä E, Aromaa A, Lönnqvist J. Interventions in relation to occupational burnout: the population-based health 2000 study. Journal of Occupational and Environmental Medicine 2007;49: [1.63;85./162] 130. Holma KM, Holma IA, Melartin TK, Rytsälä HJ, Isometsä ET. Long-term outcome of major depressive disorder in psychiatric patients is variable. Journal of Clinical Psychiatry 2008;69: [5.498;18./140] 131. Jylhä P, Melartin T, Rytsälä H, Isometsä E. Neuroticism, introversion and major depressive disorder traits, states or scars? Depression and Anxiety 2009;26: [4.407;23./140] 10

11 132. Sokero P, Melartin T, Rytsälä H, Leskelä U, Lestelä-Mielonen P, Isometsä E. Adequacy of, attitudes towards and adherence to treatments by suicidal and nonsuicidal depressed patients. Journal of Nervous and Mental Disease 2008;196:223-9.[1.688;89./140] 133. Rehn L, Meririnne E, Höök-Nikanne J, Isometsä E, Henriksson M. Depressive symptoms, suicidal ideation and acne: a study of male Finnish conscripts. Journal of the European Academy of Dermatology and Venereology (JEADV)2008;22: [2.826;11./62] 134. Holma KM, Melartin TK, Holma IA, Isometsä ET. Predictors for switch from major depressive disorder to bipolar type I and II disorder: a 5-year prospective study. Journal of Clinical Psychiatry2008;69: [5.498;18./140] 135. Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, Blackwood D, Curtis D, Deary IJ, Harris SE, Isometsä ET, Lawrence J, Lönnqvist J, Muir W, Palotie A, Partonen T, Paunio T, Pylkkö E-M, Robinson M, Soronen P, Suominen K, Suvisaari J, St Clair D, Gurling H, Peltonen L, Porteous D. DISC1 association, heterogeneity and allelic interplay in schizophrenia and bipolar disorder. Molecular Psychiatry 2009;14: [14.496;5./289] 136. Sihvo S, Isometsä E, Kiviruusu O, Hämäläinen J, Suvisaari J, Perälä J, Pirkola S, Saarni S, Lönnqvist J. Antidepressant utilisation patterns and determinants of short-term and nonpsychiatric use in the Finnish adult general population. Journal of Affective Disorders 2008;110: [3.383;44./140] 137. Leskelä U, Melartin T, Rytsälä H, Sokero P, Lestelä-Mielonen P, Isometsä E. The influence of major depressive disorder on objective and subjective social support: a prospective study. Journal of Nervous and Mental Disease 2008;196: [1.688;89./140] 138. Mantere O, Suominen K, Valtonen H, Arvilommi P and Isometsä E. Only half of bipolar I and II patients report prodromal symptoms. Journal of Affective Disorders 2008;111: [3.383;44./140] 139. Wahlström M, Sihvo S, Haukkala A, Kiviruusu O, Pirkola S, Isometsä E. Use of mental health services and complementary and alternative medicine in persons with common mental disorders. Acta Psychiatrica Scandinavica 2008;118:73-80.[5.605;17./140] 140. Holma IA, Holma KM, Melartin TK, Isometsä ET.Maintenance pharmacotherapy for recurrent major depressive disorder: 5-year follow-up study. The British Journal of Psychiatry 2008;193: [7.991;9./140] 141. Hämäläinen J, Isometsä E, Sihvo S, Kiviruusu O, Pirkola S, Lönnqvist J. Treatment of major depressive disorder in the Finnish general population. Depression and Anxiety. 2009;26: [4.407;23./140] 142. Jylhä P, Melartin T, Isometsä E. Relationships of neuroticism and extraversion with axis I and II comorbidity among patients with DSM-IV major depressive disorder. Journal of Affective Disorders 2009;114: [3.383;44./140] 143. Valtonen HM, Suominen K, Haukka J, Mantere O, Arvilommi P, Leppämäki S, Isometsä E. Hopelessness across phases of bipolar I or II disorder: A prospective study. Journal of Affective Disorders 2009;115:11-17.[3.383;44./140] 11

12 144. Vuorilehto MS, Melartin TK, Isometsä ET. Course and Outcome of Depressive Disorders in Primary Care: A Prospective 18-month Study. Psychological Medicine 2009;39: [5.938;14./140] 145. Melartin T, Haukka J, Rytsälä H, Jylhä P, Isometsä E. Categorical and dimensional stability of comorbid personality disorder symptoms in DSM-IV major depressive disorder. A prospective study. Journal of Clinical Psychiatry 2010;71: [5.498;18./140] 146. Leskelä U, Melartin T, Rytsälä H, Jylhä P, Sokero P, Lestelä-Mielonen P, Isometsä E. The influence of personality on objective and subjective social support among patients with major depressive disorder: a prospective study. Journal of Nervous and Mental Disease 2009;197: [1.688;89./140] 147. Valtonen HM, Suominen K, Sokero P, Mantere O, Arvilommi P, Leppämäki S, Isometsä E. How suicidal bipolar patients are depends on how suicidal ideation is defined. Journal of Affective Disorders 2009;118:48-54.[3.383;44./140] 148. Rehn LMH, Meririnne E, Höök-Nikanne J, Isometsä E, Henriksson M. Depressive symptoms and suicidal ideation during isotretinoin treatment: a 12-week follow-up study of male Finnish military conscripts. Journal of the European Academy of Dermatology and Venereology (JEADV) 2009;23: [2.826;11./62] 149. Suominen K, Mantere O, Valtonen H, Arvilommi P, Leppämäki S, Isometsä E. Gender differences in bipolar disorder type I and II. Acta Psychiatrica Scandinavica 2009;120: [5.605;17./140] 150. Kieseppä T, Eerola M, Mäntylä R, Neuvonen T, Poutanen V-P, Luoma K, Tuulio-Henriksson A, Jylhä P, Mantere O, Melartin T, Rytsälä H, Vuorilehto M, Isometsä E. Major depressive disorder and white matter abnormalities: a diffusion tensor imaging study with tract-based spatial statistics. Journal of Affective Disorders 2010;120: [3.383;44./140] 151. Arvilommi P, Suominen K, Mantere O, Leppämäki S, Valtonen HM, Isometsä E. Maintenance treatment received by patients with bipolar I and II disorders a naturalistic prospective study. Journal of Affective Disorders 2010;12: [3.383;44./140] 152. Ahola K, Virtanen M, Honkonen T, Isometsä E, Aromaa A, Lönnqvist J. Sairauspoissaolot masennushäiriöiden yhteydessä - Terveys väestötutkimuksen tuloksia. Suomen Lääkärilehti [Finnish Medical Journal] 2009;38: Melartin T, Häkkinen M, Koivisto M, Suominen K, Isometsä E. Screening of psychiatric outpatients for borderline personality disorder with the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD). Nordic Journal of Psychiatry 2009;63: [1.339;100./140] 154. Holma KM, Melartin TK, Haukka J, Holma IAK, Sokero TP, Isometsä ET. Incidence and predictors of suicide attempts in DSM-IV major depressive disorder a five-year prospective study. American Journal of Psychiatry 2010;167: [14.721;4./140] 155. Jylhä P, Mantere O, Melartin T, Suominen K, Vuorilehto M, Arvilommi P, Leppämäki S, Valtonen H, Rytsälä H, Isometsä E. Differences in neuroticism and extraversion between patients with bipolar I or II and general population subjects or major depressive disorder patients. Journal of Affective Disorders 2010;125:42-52.[3.383;44./140] 12

13 156. Mantere O, Isometsä E, Ketokivi M, Kiviruusu O, Suominen K, Valtonen HM, Arvilommi P, Leppämäki S. A prospective latent analyses study of psychiatric comorbidity of DSM-IV bipolar I and II disorders. Bipolar Disorders 2010;12: [4.965;20./140] 157. Palmu R, Suominen K, Vuola J, Isometsä E. Mental disorders among acute burn patients. Burns 2010;36: [1.88;80./198] 158. Holma I, Holma M, Melartin T, Isometsä E. Treatment attitudes and adherence of psychiatric patients with major depressive disorder: A five-year prospective study. Journal of Affective Disorders 2010;127: [3.383;44./140] 159. Palmu R, Suominen K, Vuola J, Isometsä E. Mental disorders after burn injury: A six-month prospective study. Burns 2011;37: [1.88;80./198] 160. Palmu R, Suominen K, Vuola J, Isometsä E. Psychiatric consultation and care after acute burn injury: A six-month naturalistic prospective study. General Hospital Psychiatry 2010;33:16-22.[2.606;58./140] 161. Holma M, Melartin T, Holma I, Paunio T, Isometsä E. Family history of psychiatric disorders and the outcome of psychiatric patients with DSM-IV major depressive disorder. Journal of Affective Disorders 2011;131: [3.383;44./140] 162. Tuulio-Henriksson A, Perälä J, Saarni S, Isometsä E, Koskinen S, Lönnqvist J, Suvisaari J. Cognitive functioning in severe psychiatric disorders: a general population study. European Archives of Psychiatry and Clinical Neuroscience 2011;261: [3.525;38./140] 163. Jylhä P, Mantere O, Melartin T, Suominen K, Vuorilehto M, Arvilommi P, Holma I, Holma M, Leppämäki S, Valtonen H, Rytsälä H, Isometsä E. Differences in temperament and character dimensions in patients with bipolar I or II or major depressive disorder and general population subjects. Psychological Medicine 2011;41: [5.938;14./140] 164. Soronen P, Mantere O, Melartin T, Suominen K, Vuorilehto M, Rytsälä H, Arvilommi P, Holma I, Holma M, Jylhä P, Valtonen H, Haukka J, Isometsä E, Paunio T. P2RX7 Gene is associated consistently with mood disorders and predicts clinical outcome in three clinical cohorts. American Journal of Medical Genetics part B: Neuropsychiatric Genetics 2011;156B: [3.416;42./140] 165. Palmu R, Suominen K, Vuola J, Isometsä E. Mental disorders after burn injury: A prospective study. Burns 2011;37: [1.88;80./198] 166. Ahola K, Virtanen M, Honkonen T, Isometsä E. Common mental disorders and subsequent work disability: a population-based Health 2000 Study. Journal of Affective Disorders 2011; 134: [3.383;44./140] 167. Pulkki-Råback L, Ahola K, Elovainio M, Kivimäki M, Hintsanen M, Isometsä E, Lönnqvist J, Virtanen M. Socio-economic position and mental disorders in a working-age Finnish population: the health 2000 study. European Journal of Public Health 2011;22: [2.459;49./160] 168. Riihimäki KA, Vuorilehto MS, Melartin TK, Isometsä E. Five-year outcome of major depressive disorder in primary health care. Psychological Medicine 2014;44: [5.938;14./140] 169. Holma IA, Holma KM, Melartin T, Rytsälä H, Isometsä E. A five year prospective study of predictors for disability pension among patients with major depressive disorders. 13

14 Acta Psychiatrica Scandinavica 2012;125: [5.605;17./140] 170. Mantere O, Suominen K, Valtonen H, Arvilommi P, Leppämäki S, Paunio T, Isometsä E. Concomitants of family histories of mood disorders and alcoholism in a clinical cohort of bipolar I and II patients. Journal of Nervous and Mental Disease 2012; 200: [1.688;89./140] 171. Pulkki-Råback L, Kivimäki M, Ahola K, Joutsenniemi K, Elovainio M, Rossi H, Puttonen S, Koskinen S, Isometsä E, Lönnqvist J, Virtanen M. Living alone and antidepressant medication use: a prospective study in a working-age population. BMC Public Health 2012;12:236. [2.264;53./162] 172. Lindberg NC, Partonen T, Tani PPJ, Rytsälä H, Suominen K, Isometsä ET. Actigraphy as an indicator for state of bipolar disorder. Psychiatria Fennica 2012;43: Mantere O, Soronen P, Uher R, Ketokivi M, Jylhä P, Melartin T, Paunio T, Isometsä E. Neuroticism mediates the effect of P2RX7 on outcomes of mood disorders. Depression and Anxiety 2012;29: [4.407;23./140] 174. Tuominen L, Salo J, Hirvonen J, Någren K. Laine P, Melartin T, Isometsä E, Viikari J, Raitakari O, Keltikangas-Järvinen L, Hietala. Temperament trait Harm Avoidance associates with µ- opioid receptor availability in prefrontal cortex: A PET study using [11C]Carfentanil. Neuroimage 2012;61: [6.357;1./14] 175. Jylhä P, Ketokivi M, Mantere O, Melartin T, Holma M, Rytsälä H, Isometsä E. Do antidepressants change personality? A five-year observational study. Journal of Affective Disorders 2012;142: [3.383;44./140] 176. Uher R, Mantere O, Suominen K, Isometsä E. Typology of clinical course in bipolar disorder based on 18-month naturalistic follow up. Psychological Medicine 2013;43: [5.938;14./140] 177. Tuominen L, Salo J, Hirvonen J, Någren J, Laine P, Melartin T, Isometsä E, Viikari J, Cloninger C R, Raitakari O, Hietala J, Keltinkangas-Järvinen L. Temperament, Character and Serotonin activity in the human brain: A Positron Emission Tomography Study Based on a General Population Cohort. Psychological Medicine 2013;43: [5.938;14./140] 178. Chiramberro M, Lindberg N, Isometsä E, Kähkönen S, Appelberg B. Repetitive transcranial magnetic stimulation induced seizures in an adolescent patient with major depression: a case report. Brain Stimulation 2013;6: [4.399;25/.192] 179. Riihimäki K, Vuorilehto M, Melartin T, Haukka J, Isometsä E. Incidence and predictors of suicidal Attempts among Primary-Care Patients with Depressive Disorders: A Five-Year Prospective Study. Psychological Medicine 2014; 44: [5.938;14./140] 180. Holma I A K, Holma K M, Melartin T K, Ketokivi M, Isometsä ET. Depression and smoking: a five-year prospective study of patients with major depressive disorder. Depression and Anxiety 2013;30: [4.407;23./140] 181. Jylhä P, Ketokivi M, Mantere O, Melartin T, Suominen K, Vuorilehto M, Holma M, Holma I, Isometsä E. Temperament, character and personality disorders. European Psychiatry 2013;28: [3.439;40./140] 14

15 182. Melartin T, Mantere O, Ketokivi M, Isometsä E. A prospective latent analyses study of axis I psychiatric comorbidity of DSM-IV major depressive disorder. Psychological Medicine 2014;44: [5.938;14./140] 183. Vuorilehto M, Valtonen H, Melartin T, Sokero P, Suominen K, Isometsä E. Method of assessment determines prevalence of suicidal ideation among patients with depression. European Psychiatry 2014;29: [3.439;40./140] 184. Kieseppä T, Mäntylä R, Tuulio-Henriksson A, Luoma K, Mantere O, Ketokivi M, Holma M, Jylhä P, Melartin T, Suominen K, Vuorilehto M, Isometsä E. White matter hyperintensities and cognitive performance in adult patients with bipolar I, bipolar II, and major depressive disorders. European Psychiatry 2014;29: [3.439;40./140] 185. Arvilommi A, Suominen K, Mantere O, Leppämäki S, Valtonen H M, Isometsä E. Predictors of Adherence to Psychopharmacological and Psychosocial Treatment in Bipolar I or II Disorders an 18-month Prospective Study. Journal of Affective Disorders 2014;155:110-7.[3.383;44./140] 186. Riihimäki K, Vuorilehto M, Isometsä E. Borderline Personality Disorder among Primary Care Depressive Patients: A Five-Year Study. Journal of Affective Disorders 2014;155: [3.383;44./140] 187. Holma M, Haukka J, Suominen K, Valtonen H M, Mantere O, Melartin T K, Sokero P, Oquendo M A, Isometsä E T. Differences in incidence of suicide attempts between bipolar I and II disorders and major depressive disorder. Bipolar Disorders 2014;16: [4.965;20./140] 188. Rosenström T, Jylhä P, Cloninger CR, Hintsanen M, Elovainio M, Mantere O, Pulkki-Råback L, Riihimäki K, Vuorilehto M, Keltikangas-Järvinen L, Isometsä E. Temperament and character traits predict future burden of depression. Journal of Affective Disorders 2014;158: ;44./140] 189. Riihimäki K, Vuorilehto M, Isometsä E. A 5-year prospective study of predictors for functional and work disability among primary care patients with depressive disorders. European Psychiatry 2015;30:51-7.[3.439;40./140] 190. Isometsä E, Sund R, Pirkola S. Post-discharge suicides of inpatients with bipolar disorder in Finland. Bipolar Disorders 2014;16: [4.965;20./140] 191. Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Cheung EYW, Conell J, Del Zompo M, Dodd s, Etain B, Fagiolini A, Frye MA, Fountoulakis K, Garneau-Fournier J, Gonzalez-Pinto A, Harima H, Hassel S, Henry C, Iacovides A, Isometsä ET, Kapczinski F, Kliwicki S, König B, Krogh R, Kunz M, Lafer B, Larsen ER, Lewitzka U, Lopez-Jaramillo C, MacQueen G, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, Monteith S, Morken G, Munoz R, Nery FG, O'Donovan C, Osher Y, Pfennig A, Quiroz D, Ramesar R, Rasgon N, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Scippa AM, Severus E, Simhandl C, Stein D, Strejilevich S, Sulaiman AH, Suominen K, Tagata H, Tatebayashi Y, Torrent C, Vieta E, Viswanath B, Wanchoo MJ, Zetin M, Whybrow PC. Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study. Journal of Affective Disorders 2014;167: [3.383;44./140] 192. Schaffer A, Isometsä ET, Tondo L, Moreno D, Turecki G, Reis C, Cassidy F, Sinyor M, Azorin J- M, Kessing LV, Ha K, Goldstein T, Weizman A, Beautrais A, Chou Y-H, Diazgranados N, Levitt AJ, Zarate CA, Rihmer Z, Yatham L. International Society for Bipolar Disorders Task Force on 15

16 Suicide: Meta-analyses and Meta-Regression of Correlates of Suicide Attempts and Suicide Deaths in Bipolar Disorder. Bipolar Disorders 2015;17:1-16.[4.965; 20./140] 193. Komulainen E, Meskanen K, Lipsanen J, Lahti J, Jylhä P, Melartin T, Wichers M, Isometsä E, Ekelund J. The Effect of Personality on Daily Life Emotional Processes. Plos One 2014; 9:e doi: /journal.pone [3.234;8./56] 194. Pallaskorpi S, Suominen K, Ketokivi M, Mantere O, Arvilommi P, Valtonen H, Leppämäki S, Isometsä E. Five-Year Outcome of Bipolar I and II Disorder: Findings of the Jorvi Bipolar Study. Bipolar Disorders 2015; 17: [4.965;20./140] 195. Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Cheung EYW, Conell J, Del Zompo M, Dodd S, Etain B, Fagiolini A, Frye MA, Fountoulakis KN, Garneau-Fournier J, Gonzalez-Pinto A, Gottlieb JF, Harima H, Hassel S, Henry C, Iacovides A, Isometsä ET, Kapczinski F, Kliwicki S, König B, Krogh R, Kunz M, Lafer B, Larsen ER, Lewitzka U, Lopez- Jaramillo C, MacQueen G, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, Monteith S, Morken G, Munoz R, Nery FG, O'Donovan C, Osher Y, Pfennig A, Quiroz D, Ramesar R, Rasgon N, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Scippa ÂM, l Severus E, Simhandl C, Stein D, Strejilevich S, Sulaiman AH, Suominen K, Tagata H, Tatebayashi Y, Torrent C, Vieta E, Viswanath B, Wanchoo MJ, Zetin M, Whybrow PC. Influence of birth cohort on age of onset cluster analysis in bipolar I disorder. European Psychiatry 2015;30: [3.439;40./140] 196. Palmu R, Partonen T, Suominen K, Vuola J, Isometsä E. Health-related quality of life 6 months after burns among hospitalized patients: predictive importance of mental disorders and burn severity. Burns 2015;41:742-8.[1.88;80./198] 197. Rosenström T, Jylhä P, Pulkki-Råback L, Holma M, Raitakari OT, Isometsä E, Keltikangas- Järvinen L. Long-term personality changes and predictive adaptive responses after depressive episodes. Evolution & Human Behavior 2015: (in press, published online). [3.13;3./14] 198. Jylhä PJ, Rosenström T, Mantere O, Suominen K, Melartin TK, Vuorilehto MS, Holma MK, Riihimäki KA, Oquendo MA, Keltikangas-Järvinen L, Isometsä ET. Temperament, character and suicide attempts in unipolar and bipolar mood disorders. Journal of Clinical Psychiatry 2015; (accepted for publication) [5.498;18./140] 199. Palmu R, Partonen T, Suominen K, Vuola J, Isometsä E. Functioning, disability and social adaptation six months after burn injury. Journal of Burn Care & Research 2015; (Epub ahead of print).[1.425;105./198] 200. Suominen K, Salminen E, Lähteenmäki S, Tupala T, Isometsä E. Validity and reliability of the Finnish version of the Functioning Assessment Short Test (FAST) in bipolar disorder. International Journal of Bipolar Disorders 2015: /s (Epub ahead of print) Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Baune BT, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Cheung EYW, Conell J, Del Zompo M, Dodd S, Etain B, Fagiolini A, Frye MA, Fountoulakis KN, Garneau- Fournier J, Gonzalez-Pinto A, Gottlieb JF, Harima H, Hassel S, Henry C, Iacovides A, Isometsä ET, Kapczinski F, Kliwicki S, König B, Krogh R, Kunz M, Lafer B, Larsen ER, Lewitzka U, Lopez- Jaramillo C, MacQueen G, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, 16

17 Monteith S, Morken G, Munoz R, Nery FG, O'Donovan C, Osher Y, Pfennig A, Quiroz D, Ramesar R, Rasgon N, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Miranda- Scippa A, Severus E, Simhandl C, Stein DJ, Strejilevich S, Sulaiman AH, Suominen K, Tagata H, Tatebayashi Y, Torrent C, Vieta E, Viswanath B, Wanchoo MJ, Zetin M, Whybrow PC. Influence of light exposure during early life on the age of onset of bipolar disorder. Journal of Psychiatric Research 2015;64:1-8. [3.957;28./140] 202. Palmu R, Partonen T, Suominen K, Vuola J, Isometsä E. Return to work at six months after burn injury: A prospective study at the Helsinki Burn Center. Burns 2015; /j.burns (Epub ahead of print). [1.88;80./198] 203. Baryshnikov I, Aaltonen K, Koivisto M, Näätänen P, Karpov B, Melartin T, Heikkinen M, Ketokivi M, Joffe G, Isometsä E. Differences and overlap in self-reported symptoms of bipolar disorder and borderline personality disorder. European Psychiatry 2015;30: [3.439;40./140] 204. Komulainen E, Heikkilä R, Meskanen K, Raij T, Nummenmaa L, Lahti J, Jylhä P, Melartin T, Harmer C, Isometsä E, Ekelund J. A single dose of mirtazapine attenuates neural responses to self-referential processing. Journal of Psychopharmacology 2015; doi: / (Epub ahead of print). [3,593; 36./140] 205. Arvilommi P, Suominen K, Mantere O, Valtonen H, Leppämäki S, Isometsä E. Predictors of long-term work disability among patients with type I and II bipolar disorder a prospective 18-month follow-up study. Bipolar Disorders 2015; doi: /bdi (Epub ahead of print). [4.965;20./140] 206. Jylhä P, Rosenström T, Mantere O, Suominen K, Melartin T, Vuorilehto M, Holma KM, Riihimäki K, Oquendo MA, Keltikangas-Järvinen L, Isometsä ET. Personality disorders and suicide attempts in unipolar and bipolar mood disorders. Journal of Affective Disorders 2016; 190: [3.383;44./140] 207. Riihimäki K, Vuorilehto M, Jylhä P, Isometsä E. Response style and severity and chronicity of depressive disorders in primary health care. European Psychiatry 2016; (in press). [3.439;40./140] 208. Aaltonen K, Näätänen P, Heikkinen M, Koivisto M, Baryshnikov I, Karpov B, Oksanen J, Melartin T, Suominen K,, Joffe G, Paunio T, Isometsä E. Differences and Similarities of Risk Factors for Suicidal Ideation and Attempts among Patients with Depressive or Bipolar Disorders. Journal of Affective Disorders 2016; (in press) [3.383;44./140] 209. Baryshnikov I, Suvisaari J, Aaltonen K, Koivisto M, Näätänen P, Karpov B, Melartin T, Oksanen J, Suominen K, Heikkinen M, Paunio P, Joffe G, Isometsä E. Self-reported symptoms of schizotypal and borderline personality disorder in patients with mood disorders.. European Psychiatry 2016; (accepted for publication). [3.439;40./140] 1.2 Peer-reviewed review articles 1. Isometsä E. Course, outcome and suicide risk in bipolar disorders. A review. Psychiatria Fennica 1993;24:

18 2. Isometsä E. Vakavien masennustilojen kulku ja ennuste. Duodecim 1994;110: Isometsä E, Henriksson M, Lönnqvist J. Masennustilat ja itsemurha. Duodecim 1994;110: Henriksson M, Isometsä E, Huttunen MO, Lönnqvist J. Masennustilojen diagnostiikan keskeisiä käsitteitä ja ongelmia. Duodecim 1994;110: Isometsä E. Suicide in Major Mood Disorders. Dissertation. Publications of the National Public Health Institute, KTL A5/1994.Helsinki, Yliopistopaino, 1994 (includes publications 1,6,7,8,9). 6. Lönnqvist JK, Henriksson MM, Isometsä ET, Marttunen MJ, Heikkinen ME, Aro HM, Kuoppasalmi KI. Mental disorders and suicide prevention. Psychiatry and Clinical Neurosciences 1995;49(Suppl.1):S Lönnqvist J, Aro H, Heikkinen M, Heilä H, Henriksson M, Isometsä E, Kuurne K, Marttunen M, Ostamo A, Pelkonen S, Pirkola S, Suokas J, Suominen K. Suicide, attempted suicide and suicide prevention. Crisis 1995;16(4): Isometsä E. Masennuslääkettä masentuneelle? Suomen Lääkärilehti1996;51: Isometsä E. Completed suicide in mood disorders in Finland - A review. Psychiatria Fennica 1996;27: Pirkola S, Isometsä E, Heikkinen M, Lönnqvist J. Työelämä vaikuttaa alkoholin ongelmakäyttäjien itsemurhien viikoittaiseen vaihteluun. Duodecim 1998;114: Isometsä E. Kaksisuuntaisen mielialahäiriön diagnoosi ja kulku. Duodecim 1999;115: Isometsä E. Hypomanioita ja masennustiloja tyypin II bipolaarihäiriö. Duodecim 1999;115: Heila H, Isometsä E. Suicide mortality in schizophrenia. The Journal of the California Alliance for the Mentally Ill 1999;10(2): Isometsä ET. Suicide. Current Opinion in Psychiatry 2000;13:143-7.[3.053, 39./129] 15. Melartin T, Isometsä E. Comorbidity of major depressive disorder a review. Psychiatria Fennica 2000: Isometsä E. Psychological autopsy studies - a review. European Psychiatry 2001;16: Pirkola S, Suominen K, Isometsä E. Suicide in alcohol dependent individuals: Epidemiology and management. CNS Drugs 2004;16: Isometsä E, Lindfors O, Pirkola S, Seppälä I, Salminen JK, Luutonen S, Marttunen M, Mattila M, Jäättelä A. The National Finnish Current Care Guidelines for the Treatment of Depression- An overview. Psychiatria Fennica 2003;34: Isometsä E. Suicidal behaviour in mood disorders. Psychiatria Fennica 2003;34:

19 20. Suomen Psykiatriyhdistys ja Suomalainen Lääkäriseura Duodecim [Finnish Psychiatric Association and Finnish Medical Society Duodecim] (Isometsä E, Lindfors O, Luutonen S, Mattila M, Marttunen M, Pirkola S, Salminen JK, Seppälä I). Depressio. Käypä hoito -suositus [Depression. Current Care Guidelines] Duodecim 2004;120: Isometsä E, Syvälahti E. Lääkeresistentin depression lääkehoidon suuntaviivoja. [Alternatives of the pharmacotherapy for refractory depression] Duodecim 2004;120: Isometsä E. Suicide in Bipolar I Disorder in Finland- Psychological autopsy findings from The National Suicide Prevention Project in Finland. Archives of SuicideResearch2005;9: [1.530, 56./117]. 23. Koivisto M, Isometsä E. Epävakaan persoonallisuushäiriön kliininen kuva ja ennuste. Suomen Lääkärilehti 2005;45: Suomen Psykiatriyhdistys ja Suomalainen Lääkäriseura Duodecim [Finnish Psychiatric Association and Finnish Medical Society Duodecim] (Isometsä E, Lindfors O, Luutonen S, Mattila M, Marttunen M, Pirkola S, Salminen JK, Seppälä I). Depressio. Käypä hoito -suositus. Tiivistelmä. [Depression. Current Care Guidelines. Extended abstract] Duodecim 2005;121: Koivisto M, Keinänen M, Isometsä E. Epävakaan persoonallisuushäiriön hoito. Duodecim 2007;123: Isometsä E. Kaksisuuntainen mielialahäiriö (maanis-depressiivisyys). Duodecim 2007;123: Arvilommi P, Suominen K, Mantere O, Leppämäki S, Valtonen H, Isometsä E. Lääkehoidon toteutuminen kaksisuuntaisessa mielialahäiriössä. Duodecim 2007;123: Suomen Psykiatriyhdistys ja Suomalainen Lääkäriseura Duodecim [Finnish Psychiatric Association and Finnish Medical Society Duodecim] (Suominen K, Hintikka J, Kampman O, Kieseppä T, Korkeila K, Leinonen E, Oksanen J, Pirinenen M, Sorvaniemi M, Tuulio-Henriksson A, Valtonen H, Isometsä E) Kaksisuuntainen mielialahäiriö. Käypä hoito -suositus. [Bipolardisorder. Current Care Guidelines.] Duodecim 2008; 124: Isometsä E. Depression tunnistaminen ja diagnostiikka. Duodecim 2009;125: Melartin T, Isometsä E. Miksi ihminen masentuu? Duodecim 2009;125: Suomen Psykiatriyhdistys ja Suomalainen Lääkäriseura Duodecim [Finnish Psychiatric Association and Finnish Medical Society Duodecim] (Isometsä E, Jousilahti P, Lindfors O, Luutonen S, Marttunen M, Pirkola S, Salminen J K, Kinnunen E, Pasternack I, Syvälahti E, Vuorilehto M) Depressio. Käypä hoito -suositus. [Depression. Current Care Guidelines.] Duodecim Suomen Psykiatriyhdistys ja Suomalainen Lääkäriseura Duodecim [Finnish Psychiatric Association and Finnish Medical Society Duodecim] (Suominen K, Hintikka J, Kampman O, Kieseppä T, Korkeila K, Leinonen E, Oksanen J, Pirinen M, Sorvaniemi M, Tuulio-Henriksson A, Valtonen H, Isometsä E) Kaksisuuntainen mielialahäiriö. Käypä hoito -suositus. Päivitetty [Bipolar disorder. Current Care Guidelines. Updated ] Duodecim Suomen Psykiatriyhdistys ja Suomalainen Lääkäriseura Duodecim [Finnish Psychiatric Association and Finnish Medical Society Duodecim] (Isometsä E, Kinnunen E, Kivekäs T, Koponen H, Lappalainen J, Lindfors O, Marttunen M, Pirkola S, Jousilahti P, Tuunainen 19

20 A.;Antila P, Raaska K, Sten berg J_H, Vuorilehto M. Syvälahti E, Vuorilehto M). Depressio. Käypä hoito suositus. Päivitetty [Depression. Current Care Guidelines. Updated ] Duodecim Schaffer A, Isometsä ET, Tondo L, Moreno DH, Sinyor M, Kessing LV, Turecki G, Weizman A, Azorin J-M, Ha K, Reis C, Cassidy F, Goldstein T, Rihmer Z, Beautrais A, Chou Y-H, Diazgranados N, Levitt AJ, Zarate CA Jr, Yatham L. Epidemiology, Neurobiology and Pharmacological Interventions Related to Suicide Deaths and Suicide Attempts in Bipolar Disorder: Part I of a Report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder. Australian & New Zealand Journal of Psychiatry 2015;49: Schaffer A, Isometsä ET, Azorin J-M, Cassidy F, Goldstein T, Rihmer Z, Sinyor M, Tondo L, Moreno DH, Turecki G, Reis C, Kessing LV, Ha K, Weizman A, Beautrais A, Chou Y-H, Diazgranados N, Levitt AJ, Zarate CA Jr, Yatham L. A Review of Factors Associated with Greater Likelihood of Suicide Attempts and Suicide Deaths in Bipolar Disorder: Part II of a Report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder. Australian & New Zealand Journal of Psychiatry 2015; 49: Simoila L, Isometsä E, Halmesmäki E, Sailas E, Suvisaari J, Gissler M, Lindberg N. Skitsofreniapotilaan raskaus ja äitiys. Duodecim 2016: (painossa). II. OTHER SCIENTIFIC PUBLICATIONS 2.1. Other reviews 1. Isometsä E, Henriksson M, Aro H, Heikkinen M, Kuoppasalmi K, Lönnqvist J. Itsemurhaa edeltänyt vakava masennustila ja sen hoito. Kirjassa: J Lönnqvist, H Aro, M Marttunen, eds. Itsemurhat Suomessa 1987-projekti.Toteutus, aineisto ja tutkimustuloksia. STAKESin tutkimuksia 25/93. Jyväskylä, Gummerus, 1993: Henriksson M, Aro H, Kuoppasalmi K, Marttunen M, Heikkinen M, Isometsä E, Lönnqvist J. Mielenterveyden häiriöt ja itsemurha. Kirjassa: J Lönnqvist, H Aro, M Marttunen, eds. Itsemurhat Suomessa 1987-projekti.Toteutus, aineisto ja tutkimustuloksia. STAKESin tutkimuksia 25/93. Jyväskylä, Gummerus, 1993: Isometsä E. Harva itsemurhaan päätynyt saanut apua masennustilaan. Kansanterveys 1996;6:3. 4. Lönnqvist J, Henriksson M, Isometsä E, Marttunen M, Heikkinen M, Aro H, Kuoppasalmi K. Seishinshogai to jijatsuyobou [in japanese] In: Seishinigaku kara kangaeru sei to shi (Mental disorder and suicide prevention). Tokyo, Kongo Shuppan, 1997: Isometsä E. Kun mielenterveys horjuu.kirjassa: Elämäntaidon ja selviytymisen kirja. Porvoo, WSOY, 1997: Isometsä E. Onko uupumus depressiota? Käytännön Lääkäri 1998;41(4):