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PROGRAM Updated 4.6.2019 Wednesday, June 5 11:00- Registration and coffee 13:00-13:30 Opening of symposium Pekka Jäkälä, Chair of the Organizing Committee Mikael von und zu Fraunberg, Neurocenter Finland Afternoon session I: A global action against stroke Chair: Pekka Jäkälä, Neurocenter, Kuopio University Hospital and Jukka Jolkkonen, Neurology, University of Eastern Finland 13:30-14:15 International collaborative efforts in stroke research Julie Bernhardt, The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia 14:15-15:00 Cell-based Therapie for Stroke and International Guidelines from the STEPS Conferences Sean Savitz, Institute for Stroke and Cerebrovascular Disease, UTHealth, Houston, TX, USA 15:00-15:30 Coffee and exhibition Afternoon session II: From heat to hypercoagulation - Uncommon stroke risk factors and uncommon measures of prevention Chair: Jukka Putaala, Department of Neurology, Neurocenter, Helsinki University Hospital 15:30-16:00 New insights on hypercoagulation and ischemic stroke Bob Siegerink, Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany 16:00-16:30 Emerging risk factors for and secondary prevention after cerebral venous thrombosis Jonathan Coutinho, Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands 16:30-17:00 Sauna bathing and prevention of stroke and cardiovascular disease Peter Willeit, Department of Neurology & Neurosurgery, Medical University of Innsbruck, Austria 18:00- Kallavesi by boat, smoke sauna and local dinner

Thursday, June 6 Morning session I: Recanalization therapy - Sponsored by Stryker Chair: Perttu Lindsberg, Department of Neurology, Neurocenter, Helsinki University Hospital 08:30-09:15 Therapeutic windows of stroke thrombolysis Götz Thomalla, The Universitätsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany 09:15-10:00 The importance of the first pass, tips and tricks to achieve it Marc Ribo, Stroke Unit, Department of Neurology, Vall d'hebron University Hospital, Barcelona, Spain 10:00-10:30 Coffee and exhibition Morning session II: Intracranial bleeds Chair: Timo Koivisto, Neurosurgery, KUH NeuroCenter and Atte Meretoja, Department of Neurology, Neurocenter, Helsinki University Hospital 10:30-11:00 ICH - intracerebral hemorrhage Atte Meretoja, Department of Neurology, Helsinki University Hospital, Helsinki, Finland 11:00-11:30 Time line analysis of acute SAH care in a defined population Timo Koivisto, Neurosurgery, KUH NeuroCenter, Finland 11:30-12:00 Saccular (sia) versus Fusiform (fia) intracranial aneurysm and their association to Aortic aneurysm (AA) Juha E Jääskeläinen, Neurosurgery, KUH NeuroCenter, Finland 12.00-13.00 Lunch and exhibition Afternoon session I: Stroke rehabilitation Chair: Kauko Pitkänen, VetreaNeuron, Kuopio 13:00-13:30 Patient-tailored treatment strategies in stroke Friedhelm Hummel, Brain Mind Institute, Swiss Federal Institute of Technology, Geneva, Switzerland 13:30-14:00 Web-based rehabilitation program for constraint induced movement therapy following stroke Jane Burridge, School of Health Sciences, Faculty of Environmental and Life Sciences, University of Southampton, UK 14:00-14:30 Brain-computer interface rehabilitation Christop Guger, Ph.D, CEO, G.tec, Austria 14:30-15:00 Coffee and exhibition Afternoon session II: Stroke genetics Chair: Juha E Jääskeläinen, Neurosurgery, KUH NeuroCenter 15:00-15:30 Genomics of stroke Arne Lindgren, Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden 15:30-16:00 Genomics of intracranial aneurysms Ynte Ruigrok, Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands 16:00-16:30 Genomics of brain arteriovenous malformations Juhana Frösen, Neurosurgery, KUH NeuroCenter, Finland 19:00-22:00 Banquet, Wanha Satama

Perjantai, 7.6. / Friday June 7 (in Finnish except the three first talks) Digitaaliset sovellukset AVH-kuntoutuksessa - VetreaNeuronin tukema Puheenjohtaja/Chair: Kauko Pitkänen, VetreaNeuron, Kuopio 09:00-9:45 The impact of health environment on post-stroke recovery Julie Bernhardt, The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia 09:45-10:15 Wearable technology for home-based upper limb stroke rehabilitation: assessment and therapy Jane Burridge, Professor of Restorative Neuroscience, School of Health Sciences, Faculty of Environmental and Life Sciences, University of Southampton 10:15-10:45 Kahvitauko ja näyttely / Coffee and exhibition 10:45-11:15 MAGIC Pre-Commercial Procurement: Impact on Post Stroke Rehabilitation Julie-Ann Walkden and Nicola Moran, Business Services Organisation (BSO), Belfast, Ireland 11:15-11:45 ACTIVAGE pelillistetty kotikuntoutuskonsepti Mika Luimula, dos., FT, tutkimusvastaava, Turku AMK 11:45-12:15 Miten motivaatiota ja yksilöllistä merkityksellisyyttä voidaan tukea avh-kuntoutuksessa? Tuulikki Sjögren, FT, yliopistonlehtori, Jyväskylän yliopisto 12:15-13:15 Lounas ja näyttely 13:15-13:45 Virtuaalitodellisuus aivoverenkiertohäiriöpotilaan kuntoutuksessa - Hoitajien kokemuksia virtuaalisesta kuntoutuksesta Jenny Kareinen, aluepäällikkö, Koti- ja hoivapalvelut Hyvinvointia kotiin Oy 13:45-14:15 Moniammatillinen etäkuntoutus aivoverenkiertohäiriön sairastaneille Leena Korhonen, TtM (tohtorikoulutettava), Itä-Suomen yliopisto 14:15-14:45 Musiikin vaikutus aivojen toipumiseen aivoinfarktin jälkeen Aleksi Sihvonen, LT, Helsingin yliopisto 14:45-15:15 Kahvitauko ja näyttely 15:15-15:45 Tanssi AVH-kuntoutuksessa Hanna Pohjola, Itä-Suomen yliopisto, Kuopio, Finland 15:45-16:15 16:15- Tanssiesitys Suomen Pyörätuolitanssiliitto ry Keskustelu ja tilaisuuden päätös Kauko Pitkänen

Friday, June 7 Workshops and lab visit Selected people have received a letter of approval for the demos. Joint hands-on workshop I Endovascular thrombectomy, stents and embolization Time and place: Friday 7.6.2019, Group I 8-10, Group II 10-12 and Group III 13-15, Hotel Scandic, Kuopio English description Hands on neuroendovascular workshop for mechanical trombectomy on acute stroke. Haptic high fidelity simulators are utilized for training techniques such as clot retrieval and stenting. Participants work 2 hours in pairs under expert guidance. Target audience Neuroradiologists, neurosurgeons and neurologists specializing in endovascular neurointervention Participants Maximum 12 (6 pairs) Simulator Mentis Vist G5 (two sets) https://www.mentice.com/vist-g5 Equipment Stryker Ltd Instructors 1. Petri Saari MD PhD KUH Neuroradiology, Chief physician 2. Antti Lindgren MD PhD KUH Neurosurgery 2 pairs per one instructor Technical support Jorma Greijer and Pieter Roels, Stryker Ltd

Joint hands-on workshop II Transcranial Doppler Time and place: Friday 7.6.2019, at 9:00-12.00, Hotel Scandic, Kuopio Objectives: provide participants with information on evidence-based indications for TCD in stroke introduce to TCD devices demonstrate basic TCD investigation train basics of TCD technique in guided hands-on groups demonstrated the performation of TCD bubble test (video, translated from Finnish) Program 09:00-09:20 Welcome & introduction 09:20-09:40 Evidence-based indications for TCD in stroke 09:40-10:00 Performance of basic TCD examination & bubble test 10:00-10:30 Demonstration of TCD devices and basic TCD examination 10:30-12:00 Guided hands-on in groups (M1, BA, VA) Teachers: Petra Ijäs, Risto Roine, Lauri Soinne Participants: max. 18 persons (3 demonstrations, 6 persons/demonstration) Lab visit Robot-assisted rehabilitation and motion analysis in neurorehabilitation Time and place: Friday 7.6.2019, at 10.30-12.15, in front of the Hotel Scandic (by bus) English description HUMEA laboratory features human motion capture facilities, versatile biosignal measurement systems and a collaborative robot arm. By combining robotics, motion capture and musculoskeletal modeling, new methods for upper limb rehabilitation are developed. Furthermore, motion capture is applied to analyse dance of both professional dancers and stroke survivors. Teacher: Pasi Karjalainen, University of Eastern Finland Participants: max. 30 persons