Anne Hyvärinen. A1 Peer-reviewed scientific articles

Anne Hyvärinen A1 Peer-reviewed scientific articles 116. Casas L, Espinosa A, Borràs-Santos A, Jacobs J, Krop E, Heederik D, Nemery B, Pekkanen J, Hyvärinen A, Täubel M, Zock JP. Author response to Dr Wise's letter. Occup Environ Med. 2016 Mar;73(3):215-6. doi: 10.1136/oemed-2015-103255 115. Loss GJ, Depner M, Hose AJ, Genuneit J, Karvonen AM, Hyvärinen A, Roduit C, Kabesch M, Lauener R, Pfefferle PI, Pekkanen J, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ; PASTURE study group. The Early Development of Wheeze: Environmental Determinants and Genetic Susceptibility at 17q21. Am J Respir Crit Care Med. 2016 Apr 15;193(8):889-97. doi: 10.1164/rccm.201507-1493OC 114. Brick T, Schober Y, Böcking C, Pekkanen J, Genuneit J, Loss G, Dalphin JC, Riedler J, Lauener R, Nockher WA, Renz H, Vaarala O, Braun-Fahrländer C, von Mutius E, Ege MJ, Pfefferle PI; PASTURE study group. ω-3 fatty acids contribute to the asthma-protective effect of unprocessed cow's milk J Allergy Clin Immunol. 2016 Jun;137(6):1699-1706.e13. doi: 10.1016/j.jaci.2015.10.042 113. Tirkkonen J, Täubel M, Hirvonen MR, Leppänen H, Lindsley WG, Chen BT, Hyvärinen A, Huttunen K. Evaluation of sampling methods for toxicological testing of indoor air particulate matter. Inhal Toxicol. 2016 Sep;28(11):500-507. 112. Casas L, Espinosa A, Pekkanen J, Asikainen A, Borràs-Santos A, Jacobs J, Krop EJ, Täubel M, Hyvärinen A, Heederik D, Zock JP. School attendance and daily respiratory symptoms in children: influence of moisture damage. Indoor Air. 2016 May 25. doi: 10.1111/ina.12311. [Epub ahead of print] 111. Korkalainen, M., Täubel, M., Naarala, J., Kirjavainen, P., Koistinen, A., Hyvärinen, A., Komulainen, H., Viluksela, M. Synergistic proinflammatory interactions of microbial toxins and structural components characteristic to moisture-damaged buildings. Indoor Air. 2016 Jan 25. doi: 10.1111/ina.12282. [Epub ahead of print] 110. Mensah-Attipoe, J., Reponen, T., Veijalainen, A.-M., Rintala, H., Täubel, M., Rantakokko, P., Ying, J., Hyvärinen, A., Pasanen, P. Comparison of methods for Assessing Temporal Variation of growth of Fungi on Building Materials. Microbiology 2016 Sep 20. doi: 10.1099/mic.0.000372. [Epub ahead of print] 109. Täubel, M., Karvonen, A.M., Reponen, T., Hyvärinen A., Vesper, S., Pekkanen, J. (2015) Application of the Environmental Relative Moldiness Index in Finland. Applied and Environmental Microbiology. pii: AEM.02785-15 108. Adams, R., Tian, Y., Taylor, J.W., Bruns, T.D., Hyvärinen, A., Täubel, M. (2015). Passive dust collectors for assessing airborne material. Microbiome 3(1):46. doi: 10.1186/s40168-015-0112-7

107. Mustonen, K., Karvonen,A., Kirjavainen, P., Roponen, M.,Schaub, B., Hyvärinen, A.,Frey, U., Renz, H., Pfefferle, I.J., Genuneit, J., Vaarala, O., Pekkanen, J. Moisture damage in home associates with systemic inflammation in children Indoor Air 2015 Apr 27. doi: 10.1111/ina.12216. 106. Shorter, C., Täubel, M., Pierse, N., Douwes, J., Howden-Chapman, P., Hyvärinen, A., Crane, J. Objective assessment of domestic mold contamination using qpcr. Journal of Allergy and Clinical Immunology 2015, doi: 10.1016/j.jaci.2015.06.039. 105. Valkonen, M., Wouters, I., Täubel, M., Rintala H, Lenters V, Vasara R, Genuneit J, Braun- Fahrländer C, Piarroux R, von Mutius E, Heederik D, Hyvärinen A. Bacterial exposures and associations with atopy and asthma in children. PLosOne doi 2015. 10.1371/journal.pone.0131594 104. Huttunen, K., Tirkkonen, J., Täubel, M., Krop, E., Mikkonen, S., Pekkanen, J., Heederik, D., Zock, J.-P., Hyvärinen, A., Hirvonen, M.-R. (2015) Inflammatory potential in relation to the microbial content of settled dust samples collected from moisture damaged and reference schools: Results of HITEA study. Indoor Ai doi: 10.1111/ina.12223r. 103. Tischer, C., Zock, J.-P., Valkonen, M., Doekes, G., Guerra, S., Heederik, D., Jarvis, D., Norbäck, D., Olivieri, M., Sunyer, J., Svanes, C., Täubel, M., Thiering, E., Verlato, G., Hyvärinen, A, Heinrich, J. Predictors of microbial agents in dust and respiratory health in the ECRHS. BMC Pulmonary Medicine 2015. 2;15(1):48 102. Kirjavainen, P.V., Täubel, M., Karvonen, A.M., Sulyok, M., Krska, R., Hyvärinen, A., Pekkanen, J. Microbial Secondary Metabolites in Residential Houses in Association with Moisture Damage and Asthma. Indoor Air 2015. doi: 10.1111/ina.12213. 101. Loss, G., Depner, M., Ulfman, L, van Neerven, R. J., Hose, A, Genuneit, J, Karvonen, A., Hyvarinen, A, Kaulek, V, Roduit, C, Weber, J, Lauener, R, Pfefferle, P, Pekkanen J., Vaarala, O.,Dalphin, J-C., Riedler, J., Braun-Fahrlaender, C, von Mutius, E., Ege, M. Consumption of unprocessed cow's milk protects infants from common respiratory infections Journal of allergy and clinical immunology 2015 135(1): 56-U487 100. Ruokolainen, L., von Hertzen, L., Fyhrquist, N., Laatikainen, T.Lehtomaki, J., Auvinen, P., Karvonen, A., Hyvarinen, A., Tillmann, V., Niemelä O, Knip, M., Haahtela, T, Pekkanen, J., Hanski. Green areas around homes reduce atopic sensitization in children, Allergy 2015 70( 2): 195-202 99. Karvonen, A., Hyvarinen, A., Korppi, M., Haverinen-Shaughnessy, U., Renz, H., Pfefferle, P., Remes, S., Genuneit, J., Pekkanen, J. Moisture damage and asthma: a birth cohort study. Pediatrics 2015, 135 (3):e598-606 DOI:10.1542/peds.2014-1239 98. Casas, L., Espinosa, A., Borrás-Santos, A., Jacobs, J., Krop, E., Heederik, D., Nenery, B., Pekkanen, J., Hyvärinen A., Täubel, M., Zock, J.-P. Domestic use of bleach and infections in children: a multicenter cross-sectional study. Occup Environ Med. 2015 doi: 10.1136/oemed- 2014-102701 97. Nevalainen, A., Täubel, M., Hyvärinen, A. Fungi contaminants and companions; a review on indoor fungi. Indoor Air 2015 2:125-156

96. Tischer C, Casas L, Wouters IM, Doekes G, Garcia-Esteban R, Gehring U, Hyvärinen A, Oldenwening M, Kerkhof M, Sunyer J, Standl M, Thiering E, Torrent M, Heinrich J; the HITEA study group. Early exposure to bio-contaminants and asthma up to 10 years of age: results of the HITEA study. Eur Respir J. 2015 45( 2): 328-337 95. Jacobs J, Borràs-Santos A, Krop E, Täubel M, Leppänen H, Haverinen-Shaughnessy U, Pekkanen J, Hyvärinen A, Doekes G, Zock JP, Heederik D. Dampness, bacterial and fungal components in dust in primary schools and respiratory health in schoolchildren across Europe. Occup Environ Med. 2014 Oct;71(10):704-12. doi: 10.1136/oemed-2014-102246. Epub 2014 Jul 17. PubMed PMID: 25035116 94. Leppänen HK, Täubel M, Roponen M, Vepsäläinen A, Rantakokko P, Pekkanen J, Nevalainen A, von Mutius E, Hyvärinen A. Determinants, reproducibility, and seasonal variation of bacterial cell wall components and viable counts in house dust. Indoor Air. 2014 Jul 3. doi: 10.1111/ina.12141. [Epub ahead of print] PubMed PMID: 24992650 93. Karvonen AM, Hyvärinen A, Rintala H, Korppi M, Täubel M, Doekes G, Gehring U, Renz H, Pfefferle PI, Genuneit J, Keski-Nisula L, Remes S, Lampi J, von Mutius E, Pekkanen J. Quantity and diversity of environmental microbial exposure and development of asthma: a birth cohort study. Allergy. 2014 Aug;69(8):1092-101. doi: 10.1111/all.12439. Epub 2014 Jun 13. PubMed PMID: 24931137; PubMed Central PMCID: PMC4143956 92. Leppänen HK, Nevalainen A, Vepsäläinen A, Roponen M, Täubel M, Laine O, Rantakokko P, von Mutius E, Pekkanen J, Hyvärinen A. Determinants, reproducibility, and seasonal variation of ergosterol levels in house dust. Indoor Air. 2014 Jun;24(3):248-59. PubMed PMID: 24883434 91. Roduit C, Frei R, Depner M, Schaub B, Loss G, Genuneit J, Pfefferle P, Hyvärinen A, Karvonen AM, Riedler J, Dalphin JC, Pekkanen J, von Mutius E, Braun-Fahrländer C, Lauener R; PASTURE study group. Increased food diversity in the first year of life is inversely associated with allergic diseases. J Allergy Clin Immunol. 2014 Apr;133(4):1056-64. doi: 10.1016/j.jaci.2013.12.1044. Epub 2014 Feb 6. PubMed PMID: 24508301 90. Huttunen K, Tiihonen K, Roponen M, Heederik D, Zock JP, Täubel M, Hyvärinen A, Hirvonen MR. The effect of assay type and sample matrix on detected cytokine concentrations in human blood serum and nasal lavage fluid. J Pharm Biomed Anal. 2014 Aug 5;96:151-5. doi: 10.1016/j.jpba.2014.03.034. Epub 2014 Mar 30. PubMed PMID: 24742773 89. Depner M, Fuchs O, Genuneit J, Karvonen AM, Hyvärinen A, Kaulek V, Roduit C, Weber J, Schaub B, Lauener R, Kabesch M, Pfefferle PI, Frey U, Pekkanen J, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ; PASTURE Study Group. Clinical and epidemiologic phenotypes of childhood asthma. Am J Respir Crit Care Med. 2014 Jan 15;189(2):129-3. 88. Nwaru BI, Virtanen SM, Alfthan G, Karvonen AM, Genuneit J, Lauener RP, Dalphin JC, Hyvärinen A, Pfefferle P, Riedler J, Weber J, Roduit C, Kaulek V, Braun-Fahrländer C, von

Mutius E, Pekkanen J; the PASTURE study group. Serum vitamin E concentrations at 1 year and risk of atopy, atopic dermatitis, wheezing, and asthma in childhood: the PASTURE study. Allergy. 2013 Nov 11. doi: 10.1111/all.12307. [Epub ahead of print] 87. Casas L, Tischer C, Wouters IM, Torrent M, Gehring U, Garcia-Esteban R, Thiering E, Postma DS, de Jongste J, Smit HA, Borràs-Santos A, Zock JP, Hyvärinen A, Heinrich J, Sunyer J. Early life microbial exposure and fractional exhaled nitric oxide in school-age children: a prospective birth cohort study. Environ Health. 2013 Dec 2;12:103. 86. Jacobs JH, Krop EJ, Borras-Santos A, Zock JP, Taubel M, Hyvarinnen A, Pekkanen J, Doekes G, Heederik DJ; The HITEA schools study consortium. Endotoxin levels in settled airborne dust in European schools: The HITEA school study. Indoor Air. 2013 Aug 8. doi: 10.1111/ina.12064. [Epub ahead of print]. 85. MacNeill SJ, Sozanska B, Danielewicz H, Debinska A, Kosmeda A, Boznanski A, Illi S, Depner M, Strunz-Lehner C, Waser M, Büchele G, Horak E, Genuneit J, Heederik D, Braun- Fahrländer C, von Mutius E, Cullinan P; GABRIELA study group. Asthma and allergies: is the farming environment (still) protective in Poland? The GABRIEL Advanced Studies. Allergy. 2013 Jun;68(6):771-9. 84. Borràs-Santos A, Jacobs JH, Täubel M, Haverinen-Shaughnessy U, Krop EJ, Huttunen K, Hirvonen MR, Pekkanen J, Heederik DJ, Zock JP, Hyvärinen A: Dampness and mould in schools and respiratory symptoms in children: the HITEA study. Occup Environ Med. 2013(70), s. 681-687. 83. Haverinen-Shaughnessy U, Borras-Santos A, Turunen M, Zock JP, Jacobs J, Krop EJM, Casas L, Shaughnessy R, Täubel M, Heederik D, Hyvärinen A, Pekkanen J, Nevalainen A, HITEA study group: Occurrence of moisture problems in schools in three countries from different climatic regions of Europe based on questionnaires and building inspections - the HITEA study. Indoor Air 2012;22:457-466. 82. Depner M, Ege MJ, Genuneit J, Pekkanen J, Roponen M, Hirvonen MR, Dalphin JC, Kaulek V, Krauss-Etschmann S, Riedler J, Braun-Fahrländer C, Roduit C, Lauener R, Pfefferle PI, Weber J, von Mutius E; PASTURE Study Group. Atopic sensitization in the first year of life. J Allergy Clin Immunol. 2013 Mar;131(3):781-8. doi: 10.1016/j.jaci.2012.11.048. Epub 2013 Jan 16. 81. Michel S, Busato F, Genuneit J, Pekkanen J, Dalphin JC, Riedler J, Mazaleyrat N, Weber J, Karvonen AM, Hirvonen MR, Braun-Fahrländer C, Lauener R, von Mutius E, Kabesch M, Tost J; PASTURE study group Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy. Allergy. 2013 Mar;68(3):355-64. doi: 10.1111/all.12097. Epub 2013 Jan 25. 80. Casas L, Tischer C, Wouters IM, Valkonen M, Gehring U, Doekes G, Torrent M, Pekkanen J, Garcia-Esteban R, Hyvärinen A, Heinrich J, Sunyer J. Endotoxin, extracellular polysaccharides, and β(1-3)-glucan concentrations in dust and their determinants in four European birth cohorts: results from the HITEA project. Indoor Air. 2013 Jun;23(3):208-18. doi: 10.1111/ina.12017. Epub 2012 Dec 21

79. Roponen M, Meklin T, Rintala H, Hyvärinen A, Hirvonen MR. Effect of moisture-damage intervention on the immunotoxic potential and microbial content of airborne particles and on occupants' upper airway inflammatory responses. Indoor Air. 2013 Aug;23(4):295-302. doi: 10.1111/ina.12032 78. Mustonen K, Orivuori L, Keski-Nisula L, Hyvärinen A, Pfefferle PI, Riedler J, Dalphin JC, Genuneit J, Lauener R, Roduit C, Braun-Fahrländer C, Weber J, Schaub B, von Mutius E, Pekkanen J, Vaarala O; PASTURE Study Group. Inflammatory response and IgE sensitization at early age. Pediatr Allergy Immunol. 2013 Jun;24(4):395-401. doi: 10.1111/pai.12072. Epub 2013 Apr 11. 77. Loss G, Bitter S, Wohlgensinger J, Frei R, Roduit C, Genuneit J, Pekkanen J, Roponen M, Hirvonen MR, Dalphin JC, Dalphin ML, Riedler J, von Mutius E, Weber J, Kabesch M, Michel S, Braun-Fahrländer C, Lauener R; PASTURE study group. Prenatal and early-life exposures alter expression of innate immunity genes: the PASTURE cohort study. J Allergy Clin Immunol. 2012 Aug;130(2):523-30.e9. 76. Illi S, Depner M, Genuneit J, Horak E, Loss G, Strunz-Lehner C, Büchele G, Boznanski A, Danielewicz H, Cullinan P, Heederik D, Braun-Fahrländer C, von Mutius E; GABRIELA Study Group. Protection from childhood asthma and allergy in Alpine farm environments-the GABRIEL Advanced Studies. J Allergy Clin Immunol. 2012 Jun;129(6):1470-7.e6. Epub 2012 Apr 24. 75. Stöcklin L, Loss G, von Mutius E, Genuneit J, Horak E, Braun-Fahrländer C; GABRIELA study group. Health-related quality of life does not explain the protective effect of farming on allergies. Pediatr Allergy Immunol. 2012 Sep;23(6):519-21. doi: 10.1111/j.1399-3038.2012.01305.x. Epub 2012 May 3 74. Mustonen K, Keski-Nisula L, Vaarala O, Pfefferle PI, Renz H, Riedler J, Dalphin JC, Buechele G, Lauener R, Braun-Fahrländer C, von Mutius E, Pekkanen J; PASTURE Study Group. Pediatr Allergy Immunol. 2012 Sep;23(6): Few associations between high-sensitivity C-reactive protein and environmental factors in 4.5-year-old children. 522-8. doi: 10.1111/j.1399-3038.2012.01306.x. Epub 2012 May 3. 73. Lappalainen MHJ, Hyvarinen A, Hirvonen MR, Rintala H, Roivainen J, Renz H, Pfefferle PI, Nevalainen A, Roponen M, Pekkanen J. High Indoor Microbial Levels Are Associated with Reduced Th1 Cytokine Secretion Capacity in Infancy. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 2012:159(2): 194-203. 72. Kaarakainen P, Rintala H, Meklin T, Karkkainen P, Hyvarinen A, Nevalainen A. Concentrations and Diversity of Microbes from Four Local Bioaerosol Emission Sources in Finland. Journal of the air & waste management association 2012: 62(3):370-372 71. Roduit C, Frei R, Loss G, Buchele G, Weber J, Depner M, Loeliger S, Dalphin ML, Roponen M, Hyvarinen A, Riedler J, Dalphin JC, Pekkanen J, von Mutius E, Braun- Fahrlander C, Lauener R, Group Author(s): Protection Allergy-Study Rural Env. Development of atopic dermatitis according to age of onset and association with early-life exposures JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2012: 130(1): 130-

70. Karvonen AM, Hyvarinen, A, Gehring U, Korppi M, Doekes G, Riedler J, Braun-Fahrlander C, Bitter S, Schmid S, Keski-Nisula L, Roponen M, Kaulek V, Dalphin JC, Pfefferle PI, Renz H, Buchele G, von Mutius E, Pekkanen J, PASTURE Study Grp. Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: a birth cohort study in rural areas CLINICAL AND EXPERIMENTAL ALLERGY 2012: 42(8): 1246-1256 69. Peitzsch M, Sulyok M, Taubel M, Vishwanath V, Krop E, Borras-Santos A, Hyvarinen A, Nevalainen A, Krska R, Larsson L. Microbial secondary metabolites in school buildings inspected for moisture damage in Finland, The Netherlands and Spain. JEM 2012: 14 (8): 2044-2053 68. Lampi J, Roponen M, Hyvärinen A, Hirvonen MR, Larsson L, Nevalainen A, Pekkanen J. Determinants of stimulated peripheral blood cytokine production among farming women. Int J Hyg Environ Health. 2011 Jun;214(3):205-9. Epub 2011 Mar 2. 67. Normand AC, Sudre B, Vacheyrou M, Depner M, Wouters IM, Noss I, Heederik D, Hyvärinen A, Genuneit J, Braun-Fahrländer C, von Mutius E, Piarroux R; the GABRIEL-A Study Group. Airborne cultivable microflora and microbial transfer in farm buildings and rural dwellings. Occup Environ Med. 2011 Nov;68(11):849-855. Epub 2011 Mar 24. 66. Ege MJ, Strachan DP, Cookson WO, Moffatt MF, Gut I, Lathrop M, Kabesch M, Genuneit J, Büchele G, Sozanska B, Boznanski A, Cullinan P, Horak E, Bieli C, Braun-Fahrländer C, Heederik D, von Mutius E; GABRIELA Study Group. Gene-environment interaction for childhood asthma and exposure to farming in Central Europe. J Allergy Clin Immunol. 2011 Jan;127(1):138-44, 144.e1-4. 65. Ege MJ, Mayer M, Normand AC, Genuneit J, Cookson WO, Braun-Fahrländer C, Heederik D, Piarroux R, von Mutius E; GABRIELA Transregio 22 Study Group. Exposure to environmental microorganisms and childhood asthma. N Engl J Med. 2011 Feb 24;364(8):701-9. 64. Genuneit J, Büchele G, Waser M, Kovacs K, Debinska A, Boznanski A, Strunz-Lehner C, Horak E, Cullinan P, Heederik D, Braun-Fahrländer C, von Mutius E; GABRIELA Study Group. The GABRIEL Advanced Surveys: study design, participation and evaluation of bias. Paediatr Perinat Epidemiol. 2011 Sep;25(5):436-47. 63. Loss G, Apprich S, Waser M, Kneifel W, Genuneit J, Büchele G, Weber J, Sozanska B, Danielewicz H, Horak E, van Neerven RJ, Heederik D, Lorenzen PC, von Mutius E, Braun- Fahrländer C; GABRIELA study group The protective effect of farm milk consumption on childhood asthma and atopy: the GABRIELA study. J Allergy Clin Immunol. 2011 Oct;128(4):766-773. 62. Pitkäranta M, Meklin T, Hyvärinen A, Nevalainen A, Paulin L, Auvinen P, Lignell U, Rintala H. Molecular profiling of fungal communities in settled dust in moisture-damaged buildings before and after remediation BMC Microbiol. 2011 Oct 21;11:235. 61. Täubel M, Sulyok M, Vishvanath V, Bloom E, Turunen M, Järvi K, Kauhanen E, Krska R, Hyvärinen A, Larsson L, Nevalainen A. Co-occurrence of toxic bacterial and fungal

secondary metabolites in moisture damaged indoor environments. Indoor Air. 2011 Oct;21(5):368-75. 60. Huttunen K, Kauhanen E, Meklin T, Vepsäläinen A, Hirvonen MR, Hyvärinen A, Nevalainen A. The effect of ozonization on furniture dust: microbial content and immunotoxicity in vitro. Sci Total Environ. 2010 May 1;408(11):2305-11. Epub 2010 Mar 12. PubMed PMID: 20227106. 59. Kärkkäinen PM, Valkonen M, Hyvärinen A, Nevalainen A, Rintala H. Determination of bacterial load in house dust using qpcr, chemical markers and culture. J Environ Monit. 2010 Mar;12(3):759-68. Epub 2010 Jan 20. PubMed PMID: 20445866. 58. von Hertzen L, Hyvärinen A, Laatikainen T, Mäkelä MJ, Nevalainen A, Vartiainen E, Haahtela T. Risk of atopy associated with microbial components in house dust. Ann Allergy Asthma Immunol. 2010 Mar;104(3):269-70 57. Pfefferle PI, Büchele G, Blümer N, Roponen M, Ege MJ, Krauss-Etschmann S, Genuneit J, Hyvärinen A, Hirvonen MR, Lauener R, Pekkanen J, Riedler J, Dalphin JC, Brunekeef B, Braun-Fahrländer C, von Mutius E, Renz H; PASTURE Study Group. Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: the PASTURE Study. J Allergy Clin Immunol. 2010 Jan;125(1):108-15.e1-3. Epub 2009 Dec 6. 56. Täubel M, Rintala H, Pitkäranta M, Hyvärinen A, Paulin L, Laitinen S, Pekkanen J, Nevalainen A. Characterizing the role of the occupant as a source of house dust bacteria. J Allergy Clin Immunol 2009 Oct;124(4):834-40.. 55. Karvonen A, Hyvärinen A, Roponen M, Hoffmann M, Korppi M, Remes S, von Mutius, Nevalainen A, Pekkanen J. Confirmed Moisture Damage at Home, Respiratory Symptoms and Atopy in Early Life: A Birth-Cohort Study. Pediatrics 2009:124(2):E329-E338. 54. Kaarakainen P, Rintala H, Vepsäläinen A, Hyvärinen A, Vesper S, Haugland R, Nevalainen A, Meklin T. Microbial content of house dust samples determined with qpcr. Science of the total environment 2009:407(16):4673-4680. 53. Ege MJ, Herzum I, Büchele G, Krauss-Etschmann S, Lauener RP, Bitter S, Roponen M, Remes S, Vuitton DA, Riedler J, Brunekreef B, Dalphin JC, Braun-Fahrländer C, Pekkanen J, Renz H, von Mutius E; PASTURE Study Group. Specific IgE to allergens in cord blood is associated with maternal immunity to Toxoplasma gondii and rubella virus. Allergy. 2008 Nov;63(11):1505-11. PubMed PMID: 18925886. 52. Sudre B, Vacheyrou M, Braun-Fahrländer C, Normand AC, Waser M, Reboux G, Ruffaldi P, von Mutius E, Piarroux R; PASTURE study group. High levels of grass pollen inside European dairy farms: a role for the allergy-protective effects of environment? Allergy. 2009 Jul;64(7):1068-73. Epub 2009 Feb 13. PubMed PMID: 19220219. 51. Pfefferle PI, Sel S, Ege MJ, Büchele G, Blümer N, Krauss-Etschmann S, Herzum I, Albers CE, Lauener RP, Roponen M, Hirvonen MR, Vuitton DA, Riedler J, Brunekreef B, Dalphin JC, Braun-Fahrländer C, Pekkanen J, von Mutius E, Renz H; PASTURE Study Group. Cord blood allergen-specific IgE is associated with reduced IFN-gamma production by cord blood

cells: the Protection against Allergy-Study in Rural Environments (PASTURE) Study. J Allergy Clin Immunol. 2008 Oct;122(4):711-6. Epub 2008 Aug 20. PubMed PMID: 18718651. 50. Pakarinen J, Hyvärinen A, Salkinoja-Salonen A, Laitinen S, Nevalainen A, Mäkelä M, Haahtela T, von Hertzen L. Predominance of Gram-positive bacteria in house dust in the lowallergy risk Russian Karelia. Environmental Microbiology 2008:10(12):3317-3325. 49. Ege M, Herzum I, Büchele, Krauss-Etschmann, Lauener R, Roponen M, Hyvärinen A, Vuitton DA, Riedler J, Brunekreef B, Dalphin J-C, Braun-Fahrländer, Pekkanen J, Renz H, von Mutius E. Prenatal exposure to a farm environment modifies atopic sensitization at birth Journal of allergy and clinical immunology 2008:122(2)407-412. 48. Lappalainen M, Roponen M, Hyvärinen A, Nevalainen A, Laine O, Pekkanen J, Hirvonen M- R. Exposure to environmental bacteria may have differing effects on TNF-α and IL-6 producing capacity in infants.clinical and Experimental Allergy 2008:38:1483-1492. 47. Lignell U, Meklin T, Rintala H, Hyvärinen A, Vepsäläinen A, Pekkanen J, Nevalainen A. Evaluation of quantitative PCR and culture methods for detection of house dust fungi and streptomycetes in relation to moisture damage of the house. Letters in Applied Microbiology 2008:47:303-308 46. Gehring U, Spithoven J1, Schmid S, Bitter S, Braun-Fahrländer C3, Dalphin J-C, Hyvärinen A, Pekkanen J, Riedler J, Weiland S, Büchele G7, von Mutius E, Vuitton D, Brunekreef B. Endotoxin levels in cow s milk samples from farming and non-farming families The PASTURE study. Environment International 2008:34:1132-1136. 45. Kaarakainen P, Meklin T, Rintala H, Hyvärinen A, Kärkkäinen P, Vepsäläinen A, Hirvonen M-R, Nevalainen A. Seasonal variation in airborne microbial concentrations and diversity at a landfill, urban and rural site. Clean 2008:36(7):556-563. 44. Haverinen-Shaughnessy U, Hyvärinen A, Putus T, Nevalainen A. Monitoring success of remediation: Seven case studies of moisture and mold damaged buildings. Science of the total environment 2008:399(1-3):19-27. 43. Pietarinen V-M, Rintala H, Hyvärinen A, Lignell U, Kärkkäinen P, Nevalainen A. Quantitative PCR analysis of fungi and bacteria in building materials and comparison to culture-based analysis. Journal of Environmental Monitoring 2008:10:655-663. 42. Huttunen K, Rintala H, Hirvonen M-R, Vepsäläinen A, Hyvärinen A, Meklin T, Toivola M, Nevalainen A. Indoor air particles and bioaerosols before and after renovation of moisture damaged building: Effect on biological activity and microbial flora. Environmental Research 2008:107:291-298. 41. Pitkäranta M, Meklin T, Hyvärinen A, Paulin L, Auvinen P, Nevalainen A ja Rintala H. Analysis of fungal flora in indoor dust by ribosomal DNA sequence analysis, quantitative PCR, and culture. AEM 2008:74(1):233-244.

40. Pekkanen J, Hyvärinen A, Haverinen-Shaughnessy U, Korppi M, Husman T, Nevalainen A. Moisture damage and childhood asthma a population-based incident case-control study. Eur Respir J 2007:29:1-9. 39. Hyvärinen A, Sebastian A, Pekkanen J, Larsson L, Korppi M, Putus T, Nevalainen A. Characterizing microbial exposure with ergosterol, 3-hydroxy fattyacids, and viable microbes in house dust: Determinants and association with childhood asthma. Archieves of Environmental and Occupational Health 2006:61(4):149-157 38. Korhonen K, Mähönen S, Hyvärinen A, Nevalainen A, Husman T, Korppi M. Skin test reactivity to moulds in children with newly-diagnosed asthma. Pediatrics International 2006, 48:577-581. 37. Haverinen-Shaughnessy U, Pekkanen J, Hyvärinen A, Nevalainen A, Putus T, Korppi M, Moschandreas D. Children s Homes Determinants of Moisture Damage and Asthma in Finnish Residences. Indoor Air 2006, 16 (3): 248-255. 36. Korppi M, Paldanius M, Hyvärinen A, Nevalainen A: Simkania negevensis and newly diagnosed asthma: A case-control study in 1 - to 6-year-old children. Respirology 2006, 11:80-83. 35. Hyvärinen A, Roponen M, Tiittanen P, Laitinen S, Nevalainen A, Pekkanen J. Dust sampling methods- an essential, but underestimated issue. Indoor Air 2006, 16:20-27. 34. Roponen M, Hyvärinen A, Hirvonen M, Keski-Nisula L, Pekkanen J: Change in IFN-yproducing capacity in early life and exposure to environmental microbes. Journal of Allergy Clinical Immunology 2005, 116:1048-1052. 33. Haverinen-Shaughnessy U, Hyvärinen A, Pekkanen J, Nevalainen A, Husman T, Korppi M, Halla-aho J, Koivisto J, Moschandreas D. Occurrence and characteristics of moisture damage in residential buildings as a function of occupant and engineer observations. Indoor and Built Environment 2005, 14(2):133-140 32. Meklin T, Husman T, Pekkanen J, Hyvärinen A, Hirvonen M-R, Nevalainen A. The effects of moisture damage repairs on microbial exposure and symptoms in schoolchildren. Indoor Air 2005, 15:40-47. 31. Rintala H, Hyvärinen A, Paulin L, Nevalainen A. Detection of streptomycetes in house dust - comparison of culture and PCR methods. Indoor Air 2004, 14:112-119. 30. Korppi M, Paldanius M, Hyvärinen A, Nevalainen A, Husman T. Chlamydia pneumoniae and newly diagnosed asthma: a case-control study in 1 to 6-year-old children. Respirology 2004, 9:255-259. 29. Ruoppi PI, Husman TM, Reiman MH, Nuutinen J, Hyvärinen AM, Nevalainen AI. Nasal symptoms among residents in moldy housing. Scandinavian Journal of Work and Environmental Health 2003, 29(6):461-467.

28. Korppi M, Nevalainen A. Effect of building frame and moisture damage on microbiological indoor air quality in school buildings. American Industrial Hygiene Association Journal 2003, 64:108-116. 27. Hyvärinen A, Husman T, Laitinen S, Meklin T, Taskinen T, Korppi M, Nevalainen A. Microbial exposure and mold-specific serum IgG levels among children with respiratory symptoms in 2 school buildings. Archives of Environmental Health 2003, 58(5):275-283. 26. Huttunen K, Hyvärinen A, Nevalainen A, Komulainen H, Hirvonen MR: Production of proinflammatory mediators by indoor air bacteria and fungal spores in mouse and human cell lines. ENVIRON HEALTH PERSPECT 2003;111:85-92. 25. Meklin T, Hyvärinen A, Toivola M, Reponen T, Koponen V, Husman T, Taskinen T, Korppi M, Nevalainen A: Effect of building frame and moisture damage on microbiological indoor air quality in school buildings. Am Ind Hyg Assoc J 2003;64:108-116. 24. Meklin T, Reponen T, Toivola M, Koponen V, Husman T, Hyvärinen A, Nevalainen A. Size distributions of airborne microbes in moisture damaged and reference school buildings of two construction types. Atmospheric Environment 2002, 36:6031-6039. 23. Nieminen S, Kärki R, Auriola S, Toivola M, Laatsch H, Laatikainen R, Hyvärinen A, von Wright A. Isolation and identification of Aspergillus fumigatus Mycotoxins on growth medium and some building materials. Applied and Environmental Microbiology 2002, 68(10):4871-4875. 22. Meklin T, Husman T, Vepsäläinen A, Vahteristo M, Koivisto J, Halla-aho J, Hyvärinen A, Moschandreas D, Nevalainen A. Indoor air microbes and respiratory symptoms of children in moisture damaged and reference schools. Indoor Air 2002, 12:175-183. 21. Hyvärinen A., Meklin T, Vepsäläinen A, Nevalainen A. Fungi and actinobacteria in moisturedamaged building materials concentrations and diversity. International Biodegradation and Biodeterioration 2002, 49:27-37. 20. Suutari M, Lignell U, Hyvärinen A, Nevalainen A. Media for cultivation of indoor streptomycetes. Journal of Microbiological Methods 2002, 51:411-416. 19. Taskinen T, Laitinen S, Hyvärinen A, Meklin T, Husman T, Nevalainen A, Korppi M: Moldspecific IgE antibodies in relation to exposure and skin test data in schoolchildren. Allergology International 2001, 50:239-245. 18. Nielsen KF, Huttunen K, Hyvärinen A, Anderssen B, Jarvis B, Hirvonen M-R. Metabolite profiles of Stachybotrys isolates from water-damaged buildings and their induction of inflammatory mediators and cytotoxicity in macrophages. Mycopathologia 2001, 154:201-205. 17. Jussila J, Komulainen H, Huttunen K, Roponen M, Hälinen A, Hyvärinen A, Kosma V-M, Pelkonen J, Hirvonen M-R. Inflammatory responses in mice after intratracheal instillation of spores of Streptomyces californicus isolated from indoor air of a moldy building. Toxicology and Applied Pharmacology 2001, 171(1):61-69.

16. Hyvärinen A, Reponen T, Husman T, Nevalainen A. Comparison of the indoor air quality in mold problem and reference buildings in subartic climate. Central European Journal of Public Health 2001, 3(9):133-139. 15. Hyvärinen A, Vahteristo M, Meklin T, Jantunen M, Nevalainen A, Moschandreas D. Temporal and spatial variation of fungal concentrations in indoor air. Aerosol Science and Technology 2001, 35:688-695. 14. Pernu N, Hyvärinen A, Toivola M, Nevalainen A, Harri M, Nevalainen T. Filter top cages: mouldy homes for rodents? Scandinavian Journal of Laboratory Animal Science 2000, 27(1):1-12. 13. Hirvonen MR, Ruotsalainen M, Roponen M, Hyvärinen A, Husman T, Kosma VM, Komulainen H, Savolainen K, Nevalainen A: Nitric oxide and proinflammatory cytokines in nasal lavage fluid associated with symptoms and exposure to moldy building microbes. AM J RESPIR CRIT CARE MED 2000;160:1943-1946. 12. Taskinen T, Hyvärinen A, Meklin T, Husman T, Nevalainen A, Korppi M. Asthma and respiratory infections in school children with special reference to moisture and mold problem in the school. Acta Paediatr.1999, 88:1373-1379. 11. Haverinen U, Husman T, Toivola M, Suonketo J, Pentti M, Lindberg R, Leinonen J, Hyvärinen A, Meklin T, Nevalainen A. An approch to management of critical indoor air problems in school buildings. Environmental Health Perspectives 1999, 107(3):509-514. 10. Ruotsalainen M, Hirvonen M-R, Hyvärinen A, Meklin T, Savolainen K, Nevalainen A. Cytotoxicity, production of reactive oxygen species and cytokines induced by different strains of Stachybotryssp. from moldy buildings in RAW264.7 macrophages. Environmental Toxicology and Pharmacology 1998, 6:193-199. 9. Nevalainen A, Partanen P, Jääskeläinen E, Hyvärinen A, Koskinen O, Meklin T, Vahteristo M, Koivisto J, Husman T. Prevalence of moisture problems in Finnish houses. Indoor Air 1998, 4:45-49. 8. Koskinen O, Husman T, Hyvärinen A, Reponen T, Nevalainen A. Two moldy day-care centers: a follow-up study of respiratory symptoms and infections. Indoor Air 1997, 7:262-268. 7. Rautiala S, Reponen T, Hyvärinen A, Nevalainen A, Husman T, Vehviläinen A, Kalliokoski P. Exposure to airborne microbes during the repair of moldy buildings. American Industrial Hygiene Association Journal 1996, 57:279-284. 6. Räty K, Raatikainen O, Wright A, Holmalahti J, Hyvärinen A, Nevalainen A. Biological activities of actinomycetes and molds isolated from houses with microbial problems. International Biodeterioration and Biodegradation 1995, 34:143-154. 5. Ruotsalainen M, Hyvärinen A, Nevalainen A, Savolainen K. Production of reactive oxygen metabolites by opsonized fungi and bacteria isolated from indoor air, and their interaction with soluble stimuli, fmlp and PMA. Environmental Research 1995, 69:122-131.

4. Koskinen O, Husman T, Hyvärinen A, Reponen T, Ruuskanen J, Nevalainen A. Respiratory symptoms and infections among children in a day care center with mold problems. Indoor Air 1995, 5:3 9. 3. Reponen T, Hyvärinen A, Ruuskanen J, Raunemaa T, Nevalainen A. Comparison of concentrations and size distributions of fungal spores in buildings with and without mould problems. Journal of Aerosol Science 1994, 25:8;1595 1603. 2. Hyvärinen A, Reponen T, Husman T, Ruuskanen J, Nevalainen A. Characterizing mold problem buildings: concentrations and flora of viable fungi. Indoor Air 1993:3;337 343. 1. Hyvärinen A, Martikainen P, Nevalainen A. Suitability of poor medium in counting total viable airborne bacteria. Grana 1991:30;414-417. A2 Peer-reviewed conference proceedings, book sections 55. Nevalainen A, Täubel M, Hyvärinen A. 2015. Fungi, Bacteria, and Other Biopollutants. In: Synergistic Influence of Gaseous, Particulate, and Biological Pollutants on Human Health. Ed. Pastuszka JS. CRC Press, Taylor & Francis Group. 54. Pastuszka JS, Nevalainen A, Täubel M, Hyvärinen A. 2015. Analysis of the Known Synergistic Effects of the Exposure to Selected Air Pollutants. In: Synergistic Influence of Gaseous, Particulate, and Biological Pollutants on Human Health. Ed. Pastuszka JS. CRC Press, Taylor & Francis Group. 53. Nevalainen A, Täubel M, Hyvärinen A. 2015. Fungi, Bacteria, and Other Biopollutants. In: Synergistic Influence of Gaseous, Particulate, and Biological Pollutants on Human Health. Ed. Pastuszka JS. CRC Press, Taylor & Francis Group. 52. Täubel M, Hyvärinen A. 2015. Occurence of mycotoxins in Indoor Environments. In: Environmental Mycology in Public Health. Eds. Viegas C, Pinheiro AC, Sabino R, Viegas S, Brandão J, Veríssimo C. Elsevier Academic Press. 51. Hyvärinen A, Täubel M. Assessment of Moisutre and Mold Problems the Finnish Example. Proceedings of Healthy Buildings Europe 2015, Eindhoven, paper 517. 50. Täubel M., Niitynen M., Jalkanen K., Vepsäläinen A., Reiman M., Hyvärinen A. Quantitative PCR in Microbial Assessments of Indoor Spaces. Proceedings of Healthy Buildings Europe 2015, Eindhoven, paper 518. 49. Hyvärinen a, Täubel M, Jacobs J, Leppänen H, Borras A, Krop E, Zock J-P, Heederik D, Pekkanen J, NevalainenA. A longitudinal assessment of microbial exposures in schools in relation to moisture damage and dampness. In: International Conference on Indoor Air 2014 48. Täubel M, Shorter C, Pierse N, Hyvärinen A, Crane J. Quantitative PCR determination of microbes in relation to observed measures of mould in homes. In: International Conference on Indoor Air 2014

47. Heederik D, Jacobs J, Borràs-Santos A, Krop E, Täubel M, Leppänen H, Haverinen- Shaughnessy U, Pekkanen J, Hyvärinen A, Doekes G, Zock J-P. Dampness, bacterial and fungal components in dust in primary schools and respiratory health in school children across Europe.. In: International Conference on Indoor Air 2014 46. Zock J-P, Borràs-Santos A, Jacobs J, Krop E, Huttunen K, Hirvonen M-R, Täubel M, Heederik D, Pekkanen J, Hyvärinen A. Moisture damage in primary school buildings and respiratory health effects in teachers: the HITEA longitudinal study. In: International Conference on Indoor Air 2014 45. Hyvärinen A, Peitzsch M, Täubel M, Suylok M, Vishwanath Vishwanath, Jacobs J, Borras A, Krop E, Vepsäläinen A, Zock J-P, Heederik D, Larsson L, Nevalainen A. Microbial toxins in surface swab and dust samples from school buildings in three European countries. In: 10th International Conference & Exhibition Healthy Buildings 2012 44. Valkonen M, Hyvärinen A, Täubel M, Rintala H, Pfefferle P, Genenuit J,von Mutius E Pekkanen J. Exploring associations between asthma and atopy and bacteria in house dust using DGGE. In: 10th International Conference & Exhibition Healthy Buildings 2012 43. Järvi K, Hyvärinen A, Täubel M, Sulyok M, Vishwanath V, Turunen M, Patovirta R, Tuomainen TP, Pirinen J, Pekkanen J, Nevalainen A. Järvi K. Hotes: An Intervention Study in moisture damaged homes- Preliminary Results. In: 10th International Conference & Exhibition Healthy Buildings 2012 42. Hyvärinen A, Markkanen P, Alenius H, Salkinoja-Salonen M, Nevalainen A, Leino M, Andersson M.M, Markkanen A, Täubel M, Matikainen S. Developing new toxicological methods to indicate severity of moisture and mold damage in buildings. In: 10th International Conference & Exhibition Healthy Buildings 2012 41. Täubel M, Rintala H, Pitkäranta M, Toivola T, Paulin L, Laitinen S, Pekkanen J, Hyvärinen A, Nevalainen A. Diversity, Seasonal Dynamics And Sources Of Bacteria In House Dust In: International Conference on Indoor Air 2011, Paper a333_1 40. M, Sulyok M, Täubel M, Vishwanath V, Borras A, Krop E, Vepsälainen A, Jacobs J, Zock J- P, Hyvärinen, Heederik D, Nevalainen A, Larsson L. Microbial Toxins In Surface Swab And Dust Samples From School Buildings In Three European Countries. In: International Conference on Indoor Air 2011,Paper a335_1 39. Hyvärinen A, Täubel M, Sulyok M, Vishwanath V, Turunen M, Järvi K, Patovirta R-L, Tuomainen T-P, Pirinen J, Pekkanen J, Nevalainen A. An Intervention Study In Moisture Damaged Homes. In: International Conference on Indoor Air 2011, Paper a371_5 38. Haverinen-Shaughnessy U, Turunen M, Borras A, Zock J-P, Jacobs J, Shaughnessy R, Taubel M, Hyvärinen A, Pekkanen J, Nevalainen A. Occurrence Of Dampness And Mould In Schools In Three Climatic Regions Of Europe. In: International Conference on Indoor Air 2011, Paper a381_1 37. Nevalainen A, Doekes G, Heederik D, Heinrich H, Hirvonen M-R, Hyvärinen A, Jarvis D, Krska R, Larsson L, Pekkanen P, Rintala H, Sunyer J, Täubel M, Zock J-P, Health Effects Of

Indoor Pollutants: Integrating Microbial, Toxicological And Epidemiological Approaches, In: International Conference on Indoor Air 2011,Paper a711_1 36. Nevalainen A, Rintala H, Pitkäranta M, KärkkäinenP, Valkonen V, Leppänen, Kaarakainen P, Lignell U, Täubel M, Pekkanen P, Hyvärinen J. Microbial Exposures Indoors - Links To Health In Good And Bad, In: International Conference on Indoor Air 2011, paper a981_1 37. Hyvärinen A, Kaarakainen P, Meklin T, Rintala H, Kärkkäinen P, Korppi M, Putus T, Pekkanen J, Nevalainen A: Airborne microbial levels - associations with childhood asthma and moisture damage. In: 9th International Conference & Exhibition Healthy Buildings 2009. 2009: paper 16. 36. Nevalainen A, Meklin T, Haverinen-Shaughnessy U, Putus T, Hyvärinen A: Developing national guidelines for management of moisture and mold in schools. In: 9th International Conference & Exhibition Healthy Buildings 2009. 2009: paper 24. 35. Täubel M, Rintala H, Pitkäranta M, Paulin L, Hyvärinen A, Nevalainen A: Bacteria in house dust and their sources. In: 9th International Conference & Exhibition Healthy Buildings 2009. 2009: paper 40. 34. Kontro MH, Lignell U, Hyvärinen A, Vahteristo M, Hirvonen M, Nevalainen A: Nutrient effects on ten Streptomyces spp. sporulation. In: Méndez-Vilas A ed. Communicating Current Research and Educational Topics and Trends in Applied Microbiology. 2007:137-142. (Microbiology series 1/2007). 33. Husman T, Meklin T, Vepsäläinen A, Vahteristo M, Koivisto J, Halla-aho J, Hyvärinen A, Koponen V, Nevalainen A: Respiratory infections among children in moisture damaged schools. In: Levin H, Bendy G, Cordell J ed. Indoor Air 2002. Proceedings: 9th International Conference on Indoor Air Quality and Climate. Volume 1. 2002:484-487. 32. Huttunen K, Hyvärinen A, Nevalainen A, Komulainen H, Hirvonen MR: Indoor air acteria induce more intense production of inflammatory mediators than fungal spores in mouse and human macrophages. In: Levin H, Bendy G, Cordell J ed. Indoor Air 2002. Proceedings: 9th International Conference on Indoor Air Quality and Climate. Volume 3. 2002:67-70. 31. Hyvärinen A, Husman T, Laitinen S, Meklin T, Taskinen T, Korppi M, Nevalainen A: Microbial exposure and mold specific serum IgG levels of symtomatic schoolchildren. In: Levin H, Bendy G, Cordell J ed. Indoor Air 2002. Proceedings: 9th International Conference on Indoor Air Quality and Climate. Volume 3. 2002:404-409. 30. Hyvärinen A, Pekkanen J, Halla-aho J, Husman T, Korppi M, Nevalainen A: Moisture damage at home and childhood asthma - a case-control study. In: Levin H, Bendy G, Cordell J ed. Indoor Air 2002. Proceedings: 9th International Conference on Indoor Air Quality and Climate. Volume 1. 2002:467-471. 29. Meklin T, Husman T, Pekkanen J, Hyvärinen A, Hirvonen MR, Nevalainen A: Effects of moisture damage repair on microbial exposure and health effects in schools. In: Levin H, Bendy G, Cordell J ed. Indoor Air 2002. Proceedings: 9th International Conference on Indoor Air Quality and Climate. Volume 3. 2002:416-420.

28. Haverinen U, Hyvärinen A, Husman T, Koskelo T, Laamanen P, Levamo H, Nevalainen A: Preliminary experiences on developing tools for evaluating repairs and their effects in practical situations. In: Seppänen O, Säteri J ed. Proceedings of Healthy Buildings 2000, Microbes, Moisture and Building Physics. Vol. 3. Helsinki: SIY, 2000:427-431. 27. Hyvärinen A, Vahteristo M, Meklin T, Halla-aho J, Koivisto J, Torvikoski A, Husman T, Pekkanen J, Korppi M, Nevalainen A: Classification of moisture damage level of residences by microbial sampling and technical investigations. In: Seppänen O, Säteri J ed. Proceedings of Healthy Buildings 2000, Microbes, Moisture and Building Physics. Vol. 3. Helsinki: SIY, 2000:527-530. 26. Jussila J, Komulainen H, Huttunen K, Roponen M, Hälinen A, Hyvärinen A, Nevalainen A, Kosma VM, Pelkonen J, Hirvonen MR: Development of a mouse model to study inflammatory responses induced by moldy house microbes. In: Seppänen O, Säteri J ed. Proceedings of Healthy Buildings 2000, Exposure, Human Responses and Building Investigations. Vol. 1. Helsinki: SIY, 2000:585-587. 25. Meklin T, Husman T, Vepsäläinen A, Vahteristo M, Koivisto J, Halla-aho J, Hyvärinen A, Moschandreas D, Nevalainen A: Moisture damages in schools - symptoms and indoor air microbes. In: Seppänen O, Säteri J ed. Proceedings of Healthy Buildings 2000, Exposure, Human Responses and Building Investigations. Vol. 1. Helsinki: SIY, 2000:335-339. 24. Toivola M, Meklin T, Luoto K, Hyvärinen A, Nevalainen A: Assessment of microbial damage of building material in laboratories which use different methods. In: Seppänen O, Säteri J ed. Proceedings of Healthy Buildings 2000, Microbes, Moisture and Building Physics. Vol. 1. Helsinki: SIY, 2000:375-377. 23. Vahteristo M, Hyvärinen A, Meklin T, Nevalainen A, Moschandreas D: Temporal variation of fungal concentrations in indoor air. In: Seppänen O, Säteri J ed. Proceedings of Healthy Buildings 2000, Exposure, Human Responses and Building Investigations. Vol. 1. Helsinki: SIY, 2000:373-374. 22. Hyvärinen A, Toivola M, Halla-aho J, Husman T, Kauhanen E, Koivisto J, Korppi M, Meklin T, Pekkanen J, Vahteristo M, Nevalainen A. Childhood asthma and residential moisture damage. In proceedings of INDOOR AIR 99, Edinburg, Scotland, Vol:5:541-542.. 21. Suutari M, Lignell U, Hyvärinen A, Hirvonen M-R, Nevalainen A. Nutrient and ph demands of ten mouldy building Streptomyces spp. for growth and sporulation. In proceedings of INDOOR AIR 99, Edinburg, Scotland, Vol 2:536-540. 20. Nevalainen A, Hyvärinen A, Halla-aho J, Toivola M, Meklin T, Taskinen T, Husman T. Building moisture, mold and symptoms of school children - starting an intervention study. In proceedings of Healthy Buildings/IAQ'97, Vol. 1, pp. 227 231. 19. Haverinen U, Husman T, Toivola M, Suonketo J, Lindberg R, Pentti M, Leinonen J, Hyvärinen A, Meklin T, Nevalainen A. A model to manage indoor air problems os school buildings. Healthy Buildings/IAQ 97, Vol 1, pp. 99-104.

18. Hyvärinen A, Meklin T, Reponen T, Kotimaa M, Nevalainen. Indoor air fungi during the heating season. In proceedings of the 7th International Conference on Indoor Air Quality and Climate, INDOOR AIR'96, Vol. 2:1089-1094. 17. Hyvärinen A, Reponen T, Husman T, Nevalainen A. Characterizing mold problem buildings - differeneces in indoor characteristics. In proceedings of the 7th International Conference on Indoor Air Quality and Climate, INDOOR AIR'96, Vol. 2:1125-1130. 16. Rautiala S, Reponen T, Nevalainen A, Husman T, Hyvärinen A, Kalliokoski P. Fire-fighting efforts may lead to a massive fungal exposure within one week. A case report. In proceedings of the 7th International Conference on Indoor Air Quality and Climate, INDOOR AIR'96, Vol. 2:1113-1117. 15. Nevalainen A, Husman T, Hyvärinen A, Koskinen O, Partanen P, Jääskeläinen E, Meklin T. Prevalence of moisture problems in Finnish houses. In proceedings of the 7th International Conference on Indoor Air Quality and Climate, INDOOR AIR'96, Vol. 2:865-868. 14. Nevalainen A, Partanen P, Hyvärinen A, Meklin T, Husman T, Mikkonen M, Reponen T. Buiding moisture investigation back to basics in identifying microbial problems. Indoor Air An Integrated Approach. Cold Cost, Australia 27.11. 1.12.1994. In Marawska L, Bofinger ND, Maroni M, eds. Indoor Air an Integrated Approach, Elsevier Science ltd, 1995:485-488. 13. Rautiala S, Kalliokoski P, Reponen T, Nevalainen A, Husman T, Hyvärinen A. Reducing microbial exposure during repair of moldy buildings. In proceedings of Indoor Air Quality in Practice. Moisture and cold climate solutions. Eds. Flatheim G, Berg K, Edwardsen K, 1995, p. 475-481. 12. Nevalainen A, Hyvärinen A, Pasanen A L, Reponen T. Fungi and bacteria in normal and mouldy dwellings. In: Air Quality Monographs Vol.2, eds. Samson et al. "Health implications of fungi in indoor environments", 1994: p.163-169. 11. Koskinen O, Husman T, Hyvärinen A, Reponen T, Ruuskanen J, Nevalainen A. Respiratory symptoms and infections in moldy houses: dwellings and day care centers.in: Air Quality Monographs Vol.2, eds. Samson et al. "Health implications of fungi in indoor environments", 1994: p. 211-214. 10. Hyvärinen A, Reponen T, Rautiala S, Husman T, Kalliokoski P, Nevalainen A. The concentrations and genera of fungi: components of exposure in moldy buildings. In proceedings of Healthy Buildings'94, Budapest, Vol. 2, pp. 193 197. 9. Rautiala S, Hyvärinen A, Nevalainen A, Husman T, Kalliokoski P, Tiittanen P, Reponen T. Comparison of six stage impactor and Camnea method during reparation work. In proceedings of Healthy Buildings'94, Budapest, Vol. 2, pp. 205 209 8. Nevalainen A, Hyvärinen A, Mikkonen M, Reponen T, Partanen P. Bioaerosol exposure in living environment identification and quantification of the problem.in proceedings of Healthy Buildings'94, Budapest, Vol. 2, pp. 205 209. 7. Hyvärinen A, Reponen T, Husman T, Ruuskanen J, Nevalainen A. Composition of fungal flora in mold problem houses determined with four different methods. In proceedings of the

6th International Conference on Indoor Air Quality and Climate, INDOOR AIR'93, Vol 4:273 278. 6. Reponen T, Hyvärinen A, Ruuskanen J, Raunemaa T, Nevalainen A. Size distribution of fungal spores in mold problem buildings. In proceedings of the 6th International Conference on Indoor Air Quality and Climate, INDOOR AIR'93, Vol. 4:243 248. 5. Tuomala M, Hyvärinen A, Nevalainen A, Savolainen K. Interactions of fmlp and PMA with six different fungi and two actinomycete strains on the production of reactive oxygen metabolites in human leukocytes. In proceedings of the 6th International Conference on Indoor Air Quality and Climate, INDOOR AIR'93, Vol. 1:693 698. 4. Tuomala M, Hyvärinen A, Nevalainen A, Savolainen K. Six different fungi and two actinomycete strains induced production of reactive oxygen metabolites in human leukocytes. In proceedings of the 6th International Conference on Indoor Air Quality and Climate, INDOOR AIR'93, Vol. 1:699 704. 3. Raatikainen O, Räty K, Wright A, Holmalahti J, Hyvärinen A, Nevalainen A. Biological activities of actinomycetes and molds isolated from houses with microbial problems. In proceedings of the 6th International Conference on Indoor Air Quality and Climate, INDOOR AIR'93, Vol. 4:237 241. 2. Husman T, Koskinen O, Hyvärinen A, Reponen T, Ruuskanen J, Nevalainen A. Respiratory symptoms and infections among residents in dwellings with humidity problems or mould growth. In proceedings of the 6th International Conference on Indoor Air Quality and Climate, INDOOR AIR'93, Vol. 1:171 174. 1. Koskinen O, Husman T, Hyvärinen A, Reponen T, Ruuskanen J, Nevalainen A. Respiratory symptoms and infections among children in day care centers with mould problem. In proceedings of the 6th International Conference on Indoor Air Quality and Climate, INDOOR AIR'93, Vol. 1:231 236. B Non refereed scientific articles 73. Täubel M, Karvonen AM, Reponen T, Hyvärinen A, Vesper S, Pekkanen, J. Application of the environmental relative moldiness index in Finland. Teoksessa Säteri, Jorma ja Ahola, Mervi (toim.): Sisäilmastoseminaari 2016, 269-274 (SIY raportti 34). 72. Ung-Lanki S, Turunen M, Pekkola V, Hyvärinen A. Ohjeistuksen kehittäminen koulujen sisäilmaongelmien hallintaan ja toimenpiteiden kiireellisyyden arviointiin. Teoksessa Säteri, Jorma ja Ahola, Mervi (toim.): Sisäilmastoseminaari 2016, 215-218 (SIY raportti 34). 71. Valkonen M, Täubel M, Jalkanen K, Vepsäläinen A, Hyvärinen A. QPCR-menetelmän validointi ilmanäytteille. Teoksessa Säteri, Jorma ja Ahola, Mervi (toim.): Sisäilmastoseminaari 2016, 279-282 (SIY raportti 34). 70. Täubel M, Reponen T, Pitkäranta M, Hyvärinen A, Hernandez M, Levin H. The Microbiology of the built environment (MOBE)' program - recent activities in Europe. Teoksessa Säteri, Jorma ja Ahola, Mervi (toim.): Sisäilmastoseminaari 2016, 129-130 (SIY raportti 34).

69. Leppänen H, Peltonen M, Täubel M, Komulainen H, Hyvärinen A. Otsonointi sisäympäristöissä - tiivistelmä kirjallisuuskatsauksesta. Teoksessa Säteri, Jorma ja Ahola, Mervi (toim.): Sisäilmastoseminaari 2016, 137-142 (SIY raportti 34) 68. Boor, B.E., Holopainen, R., Viitanen, A-K, Koivisto, J, Täubel, M., Vainiotalo, S., Salmi, K., Tuomi, T., Hyvärinen, A., Hämeri, K., Novoselac, A., Xu, Y. Infant exposure to resuspended particles from carpeted floording: experimental chamber study with a simplified mechanical crawling infant. In: Sisäilmastoseminaari 2015. 341-345. (SIY Raportti 33/2015) 67. Korkalainen, M., Mäki-Paakanen, J., Täubel, M., Kirjavainen, P., Koistinen, A., Hyvärinen, A., Komulainen, H., Viluksela, M. Mikrobitoksiinialtistus molekyylitasolla ja yhteisvaikutukset muiden homealtisteiden kanssa. In: Sisäilmastoseminaari 2015. 297-302. (SIY Raportti 33/2015) 66. Täubel, M., Hyvärinen, A. Occurrence of mycotoxins in indoor environments. In: Sisäilmastoseminaari. Sisäilmastoseminaari 2015. 347-352. (SIY Raportti 33/2015) 65. Valkonen, M., Jalkanen, K., Täubel, M., Peltonen, M., Vepsäläinen, A., Niittynen, M., Hyvärinen, A. Menetelmien kehitystyö mikrobikasvun toteamiseksi. In: Sisäilmastoseminaari 2015. 381-384. (SIY Raportti 33/2015) 64. Pietarinen, V-M, Tähtinen, K, Lappalainen, S., Hyvärinen, A., Holopainen, R., Reijula, K. Altistumisen arviointi sisäilmaston laatuun vaikuttavien tekijöiden perusteella. In: Sisäilmastoseminaari 2015. 19-24. (SIY Raportti 33/2015) 63. Täubel M, Shorter C, Pierse N, Hyvärinen A, Crane J. Quantitative PCR determination of microbes in relation to observed measures of mould in homes. In: Sisäilmastoseminaari 2014. Toim. Säteri J, Backman H. Espoo: Sisäilmayhdistys ry ja Aalto-yliopisto, Energiatekniikan laitos. SYI Raportti 32: 377-381. 62. Järvi K, Täubel M, Sulyok M, Vishwanath V, Patovirta R-L, Pirinen J, Syrjänen T, Krska R, Nevalainen A, Hyvärinen A, Pekkanen J. Mikrobivaurion vakavuuden vaikutukset asukkaiden kokemaan terveyteen. In: Sisäilmastoseminaari 2014. Toim. Säteri J, Backman H. Espoo: Sisäilmayhdistys ry ja Aalto-yliopisto, Energiatekniikan laitos. SYI Raportti 32: 33-36. 61. Täubel M, Sulyok M, Peitzsch M, Happo M, Vishwanath V, Jacobs J, Borras A, Jalava P, Krop E, Leppänen H, Zock J-P, Pekkanen J, Heederik D, Larsson L, Salonen RO, Krska R, Anne Hyvärinen A. Mikrobitoksiinit koulurakennuksissa ja niiden potentiaaliset lähteet. In: Sisäilmastoseminaari 2013. Toim. Säteri J, Backman H. Espoo: Sisäilmayhdistys ry ja Aaltoyliopisto, Energiatekniikan laitos. SYI Raportti 31: 41-44. 60. Markkanen P, Alenius H, Salkinoja-Salonen M, Hyvärinen A, Matikainen S, Mikkola R, Nevalainen A, Andersson M, Täubel M, Järvi K, Hirvonen M-R. Kosteus- ja homevaurion vakavuuden arviointi toksikologisten menetelmien avulla. Sisäilmastoseminaari 2011. 2011:93-98. (SIY Raportti 29/2011). 59. Peitzsch M, Suylok M, Täubel M, Vishwanath V, Jacobs j, Borras A, Krop E, Vepsäläinen A, Zock J-P, Hyvärinen A, Heederik D, Krska R, Nevalainen A, Larsson L. Mikrobien