LIFE2000 rahoitettavat hankkeet

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1 LIFE2000 rahoitettavat hankkeet Life 2000 tutkimusohjelmaan on valittu kaikkiaan 37 tutkimushanketta: 13 yksittäishanketta ja 24 konsortiota. Tekes tekee rahoituspäätöksensä sille esitetyistä projektiehdotuksista vuoden 2000 lopussa. 1. Aaltonen, Lauri Linkage disequilibrium mapping utilizing genomic mismatch scanning in the Finnish population, markkaa 2. Alitalo, Kari Functional analysis of factors governing cell growth and angiogenesis 1 3. Aro, Eva-Mari Novel gene functions and protein-protein interactions during biogenesis of photosynthetic membranes markkaa 4. Bamford, Dennis Dynamics of macromolecular assemblies and function of molecular machines Serimaa, Ritva Structural studies of dynamics of macromolecular assemblies by x-ray and neutron scattering markkaa Tuma, Roman Dynamics of macromolecular assemblies and function of molecular machines markkaa 5. Castrén, Eero Analysis of functional genomics data using self-organizing maps markkaa Kaski, Samuel Analysis of functional genomics data using self-organizing maps markaa Teknillinen korkeakoulu 6. Coffey, Eleanor

2 Stress activated protein kinase signaling in the brain, its role in stress and differentiation processes: regulation by scaffold proteins markkaa Åbo Akademi Courtney, Michael Stress activated protein kinase signaling in the brain, its role in stress and differentiation processes: regulation by scaffold proteins markkaa 7. Donner, Kristian Molecular and cellular mechanismis of the retina limiting basic visual functions markkaa 8. Hari, Riitta Temporal dynamics of human percepts and cortical functions markkaa Teknillinen korkeakoulu 9. Hietala, Jarmo Neurobiology of psychosis TYKS Castrén, Eero Neurobiology of psychosis markkaa Tanila, Heikki Neurobiology of psychosis 10. Hukkinen, Janne Socio-cultural dimensions of technological change: The case of Finnish biotechnology markkaa Teknillinen korkeakoulu 11. Häyry, Matti The ethical, legal and sociocultural aspects of bioscientific research and its applications markkaa Räikkä, Juha The ethical, legal and sociocultural aspects of bioscientific research and its applications markkaa

3 Salokannel, Marjut The ethical, legal and sociocultural aspects of bioscientific research and its applications markkaa 12. Ikonen, Elina Integration of cellular lipid dynamics and signaling in neuronal cells markkaa KTL Saarma, Mart Integration of cellular lipid dynamics and signaling in neuronal cells 13. Jacobs, Howard The human mitochondrial proteome: Genes involved in mtdna maintenance markkaa Tampereen yliopisto 14. Johnson, Mark Multidisciplinary attack on understanding G-protein coupled receptor function in the nervous systems of vertebrates Åbo Akademi Panula, Pertti Multidisciplinary attack on understanding G-protein coupled receptor function in the nervous systems of vertebrates Åbo Akademi Scheinin, Mika G-coupled receptor function Slotte, Peter Multidisciplinary attack on understanding G-protein coupled receptor function in the nervous systems of vertebrates Åbo Akademi Soini, Erkki Application of fluorescence correlation spectroscopy to study of nervous system receptors markkaa Wurster, Siegfried

4 Synthesis and application of fluorescent ligands for single receptor measurements YR 15. Jänne, Olli Androgen signaling in testicular development and differentiation markkaa Toppari, Jorma Androgen signaling in testicular development and differentiation markkaa 16. Kalimo, Hannu CADASIL: Hereditary disease of arteries causing brain infarcts and dementia markkaa TYKS 17. Kauppinen, Risto Studies of human brain functions: Implementing a high-field fmri into multimodal MEG and EEG imaging Salmelin, Riitta Studies of human brain functions: Implementing a high-field fmri into multimodal MEG and EEG imaging markkaa Teknillinen korkeakoulu Sams, Mikko Studies of human brain functions: Implementing a high-field fmri into multimodal MEG and EEG imaging markkaa Teknillinen korkeakoulu 18. Keinänen, Kari Calcium-permeable AMPA receptors: from molecules to function markkaa Pasternack, Michael Calcium-permeable AMPA receptors: from molecules to function markkaa Taira, Tomi Calcium-permeable AMPA receptors: from molecules to function markkaa

5 19. Kere, Juha From positional candidate genes to functional networks in asthma, a multifactorial disease markkaa Mannila, Heikki From positional candidate genes to functional networks in asthma, a multifactorial disease markkaa HUT Lahesmaa, Riitta From positional candidate genes to functional networks in asthma, a multifactorial disease markkaa 20. Keränen, Sirkka Functional analysis of novel yeast genes involved in protein secretion markkaa VTT 21. Meri, Seppo Comparative proteimic analysis of complement sensitive vs. resistant microbes and tumor cells Näätänen, Risto Molecular genetic and neurocognitive profiles in autistic spectrum of disorders markkaa Palotie, Leena Molecular genetic and neurocognitive profiles in autistic spectrum of disorders markkaa ULK von Wendt, Lennart Molecular genetic and neurocognitive profiles in autistic spectrum of disorders markkaa 23. Palotie, Leena Functional genomics of Finnish disease genes markkaa Kansanterveyslaitos Jalanko, Anu Functional genomics of Finnish disease genes

6 Kansanterveyslaitos Lehesjoki, Anna-Elina Functional genomics of Finnish disease genes Ulmanen, Ismo Functional genomics of Finnish disease genes markkaa Kansanterveyslaitos 24. Palva, Tapio Photoperiodism and winter hardiness in birch markkaa Heino, Pekka Photoperiodism and winter hardiness in birch markkaa Koski, Veikko Photoperiodism and winter hardiness in birch markkaa FFRI Junttila, Olavi Photoperiodism and winter hardiness in birch markkaa 25. Partanen, Juha Genomic tools for studies of gene functions in mice: generation of tissue-specific mutations using in vitro DNA transposition and site-specific recombination Frilander, Mikko Genomic tools for studies of gene functions in mice: generation of tissue-specific mutations using in vitro DNA transposition and site-specific recombination Savilahti, Harri Genomic tools for studies of gene functions in mice: generation of tissue-specific mutations using in vitro DNA transposition and site-specific recombination

7 26. Pitkänen, Asla Activity dependent molecular, cellular and network plasticity in the Amyglada - biological basis for emotional learning and epileptiogenesis markkaa Penttonen, Markku Activity dependent molecular, cellular and network plasticity in the Amyglada - biological basis for emotional learning and epileptiogenesis markkaa Ylinen, Aarne Activity dependent molecular, cellular and network plasticity in the Amyglada - biological basis for emotional learning and epileptiogenesis markkaa 27. Rauvala, Heikki Extracellular matrix-associated proteins in the development and activity-dependent plasticity of neuronal connections in brain markkaa Kilpeläinen, Ilkka Extracellular matrix-associated proteins in the development and activity-dependent plasticity of neuronal connections in brain markkaa Taira, Tomi Extracellular matrix-associated proteins in the development and activity-dependent plasticity of neuronal connections in brain markkaa 28. Romantschuk, Martin Pathogenicity islands in plant pathogenic bacteria markkaa Palva, Tapio Pathogenicity islands in plant pathogenic bacteria Saarilahti, Hannu

8 Pathogenicity islands in plant pathogenic bacteria 29. Ruskoaho, Heikki Signaling pathways for cardiac hypertrophy and heart failure markkaa Pihlajaniemi, Taina Signaling pathways for cardiac hypertrophy and heart failure markkaa Vainio, Seppo Signaling pathways for cardiac hypertrophy and heart failure markkaa 30. Saarma, Mart markkaa Airaksinen, Matti markkaa Kaila, Kai markkaa Rivera, Claudio markkaa Timmusk, Tonis markkaa Voipio, Juha markkaa 31. Soininen, Hilkka

9 Risk genes in Alzheimer's disease - proteomics and functional genomics approach markkaa 32. Söderlund, Hans A global molecular approach in the study of microbial stress markkaa VTT Kalkkinen, Nisse A global molecular approach in the study of microbial stress Penttilä, Merja A global molecular approach in the study of microbial stress markkaa VTT Sarvas, Matti A global molecular approach in the study of microbial stress Kansanterveyslaitos Ukkonen, Esko A global molecular approach in the study of microbial stress 33. Vihko, Pirkko Function of prostate-specific proteins markkaa Goldman, Adrian Structural studies of prostatic proteins markkaa Juffer, André Theoretical investigations of prostatic proteins markkaa Jänne, Olli Structure and function of prostate-specific proteins markkaa Soininen, Raija

10 Targeted alteration of the membrane bound serine protease TMPRSS markkaa 34. Väänänen, Kalervo Bone and immune cells: How estrogen regulates differentiation of the common stem cells markkaa Härkönen, Pirkko Bone and immune cells: How estrogen regulates differentiation of the common stem cells markkaa Lassila, Olli Bone and immune cells: How estrogen regulates differentiation of the common stem cells markkaa Lönnberg, Harri Bone and immune cells: How estrogen regulates differentiation of the common stem cells markkaa 35. Wikström, Mårten Structures and catalytic mechanisms of membrane proteins markkaa 36. Winqvist, Robert Genetic risk factors in breast and ovarian cancer markkaa Ylä-Herttuala, Seppo Gene therapy employing endothelial growth factors and receptors markkaa Alitalo, Kari Gene therapy employing endothelial growth factors and receptors